Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ryan M. Peterson"'
Publikováno v:
Chemistry & Biology. 21:389-397
SummaryPlatensimycin (PTM) and platencin (PTN) are potent inhibitors of bacterial fatty acid synthases and have emerged as promising antibacterial drug leads. We previously characterized the PTM and PTN biosynthetic machineries in the Streptomyces pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdda9802b70b9dc207fd50ca8d5bd3f
https://doi.org/10.1016/j.chembiol.2014.01.005
https://doi.org/10.1016/j.chembiol.2014.01.005
Autor:
Steven B. Kanner, Keith Blomenkamp, Jeffrey Teckman, Christine I. Wooddell, D. Christianson, Holly Hamilton, Ryan M. Peterson, Qili Chu, Vladimir M. Subbotin
Publikováno v:
Journal of Hepatology. 70:e592
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794fa86e9e1e7006fc2d6d3831da6c56
https://doi.org/10.1016/s0618-8278(19)31183-1
https://doi.org/10.1016/s0618-8278(19)31183-1
Autor:
Jeffrey L. Casper, Ryan M. Peterson, Michael J. Smanski, Zhiguo Yu, Ben Shen, Scott R. Rajski
Publikováno v:
Journal of Natural Products. 75:2158-2167
Platensimycin (PTM) and platencin (PTN) are potent and selective inhibitors of bacterial and mammalian fatty acid synthases and have emerged as promising drug leads for both antibacterial and antidiabetic therapies. We have previously cloned and sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545cf694e52438d1c8a4023d3d6facb2
https://doi.org/10.1021/np3005985
https://doi.org/10.1021/np3005985
Publikováno v:
Current Opinion in Chemical Biology. 16:132-141
Diterpenoid biosynthesis has been extensively studied in plants and fungi, yet cloning and engineering diterpenoid pathways in these organisms remain challenging. Bacteria are emerging as prolific producers of diterpenoid natural products, and bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab8ad1f0db4e6ee2473ba2a88e86012
https://doi.org/10.1016/j.cbpa.2012.03.002
https://doi.org/10.1016/j.cbpa.2012.03.002
Autor:
Verner P. Bingman, Ryan M. Peterson
Publikováno v:
Neurobiology of Learning and Memory. 96:353-360
The septo-hippocampal system in birds resembles that of mammals, motivating research into the function of the avian hippocampus while surprisingly little attention has been given to the septum. To investigate a possible role of the avian septum in me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29c16a9a478f8d90be3d69c0e4cfa21
https://doi.org/10.1016/j.nlm.2011.06.010
https://doi.org/10.1016/j.nlm.2011.06.010
Autor:
Jeffrey L. Casper, Shuangjun Lin, Ryan M. Peterson, Zhiguo Yu, Michael J. Smanski, Evelyn Wendt-Pienkowski, Yihua Chen, Ben Shen, Scott R. Rajski
Publikováno v:
Proceedings of the National Academy of Sciences. 108:13498-13503
Platensimycin (PTM) and platencin (PTN) are potent and selective inhibitors of bacterial and mammalian fatty acid synthases and have emerged as promising drug leads for both antibacterial and antidiabetic therapies. Comparative analysis of the PTM an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128bbd483e0b8577f9986789ecec84b3
https://doi.org/10.1073/pnas.1106919108
https://doi.org/10.1073/pnas.1106919108
Autor:
Karen Marchillo, Michael J. Smanski, David R. Andes, Zhiguo Yu, Ryan M. Peterson, Ben Shen, Scott R. Rajski
Publikováno v:
Organic Letters. 12:1744-1747
Platensimycin (1) and platencin (2) are novel antibiotic leads against multidrug resistant pathogens. The production of 2 in Streptomyces platensis MA7339 is under the control of ptnR1, a GntR-like transcriptional regulator. Inactivating ptnR1 afford
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2537410b05194b197cf6a844ff14f9
https://doi.org/10.1021/ol100342m
https://doi.org/10.1021/ol100342m
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:1299-1304
Platensimycin, which is isolated from Streptomyces platensis MA7327, and platencin, which is isolated from S. platensis MA7339, are two recently discovered natural products that serve as important antibiotic leads. Here we report on the identificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8fa3188a206a86ec4633f41101febf
https://doi.org/10.1128/aac.01358-08
https://doi.org/10.1128/aac.01358-08
Autor:
Emily A. Fergason-Cantrell, John R. Lever, Ryan M. Peterson, Rong Xu, Sarah A. Lord, Susan Z. Lever
Publikováno v:
Bioorganicmedicinal chemistry. 23(1)
Two series of novel ether analogs of the sigma (σ) receptor ligand 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503) have been prepared. In one series, the alkyl portion of the 4-methoxy group was replaced with allyl, propyl, br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b40d004c95be37a4045e19b0093dc1a
https://pubmed.ncbi.nlm.nih.gov/25468036
https://pubmed.ncbi.nlm.nih.gov/25468036
Publikováno v:
Behavioural brain research. 260
The role of the avian hippocampal formation (HF) in spatial cognition is well demonstrated. However, it remains uncertain if the avian hippocampus, like its mammalian counterpart, has a role in the integration of elements that could compose a memory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3fe1922463c7d73d211a810acbe013
https://pubmed.ncbi.nlm.nih.gov/24300891
https://pubmed.ncbi.nlm.nih.gov/24300891