Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ryan M. Heistad"'
Autor:
Maa O. Quartey, Jennifer N. K. Nyarko, Jason M. Maley, Jocelyn R. Barnes, Maria A. C. Bolanos, Ryan M. Heistad, Kaeli J. Knudsen, Paul R. Pennington, Josef Buttigieg, Carlos E. De Carvalho, Scot C. Leary, Matthew P. Parsons, Darrell D. Mousseau
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The pool of β-Amyloid (Aβ) length variants detected in preclinical and clinical Alzheimer disease (AD) samples suggests a diversity of roles for Aβ peptides. We examined how a naturally occurring variant, e.g. Aβ(1–38), interacts with
Externí odkaz:
https://doaj.org/article/986c73bc802940a9ae4cdf2d043e1a43
Autor:
Jennifer N. K. Nyarko, Maa O. Quartey, Ryan M. Heistad, Paul R. Pennington, Lisa J. Poon, Kaeli J. Knudsen, Odette Allonby, Amr M. El Zawily, Andrew Freywald, Gail Rauw, Glen B. Baker, Darrell D. Mousseau
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The serotonin (5-hydroxytryptamine, 5-HT) transporter (5-HTT) gene-linked polymorphic region (5-HTTLPR) is thought to alter 5-HT signaling and contribute to behavioral and cognitive phenotypes in depression as well as Alzheimer disease (AD). We explo
Externí odkaz:
https://doaj.org/article/37dcd3783e7d4a3f8dae0f7bd80ea29f
Autor:
Maa O. Quartey, Jennifer N. K. Nyarko, Paul R. Pennington, Ryan M. Heistad, Paula C. Klassen, Glen B. Baker, Darrell D. Mousseau
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Monoamine oxidase-A (MAO-A) and MAO-B have both been implicated in the pathology of Alzheimer disease (AD). We examined 60 autopsied control and AD donor brain samples to determine how well MAO function aligned with two major risk factors for AD, nam
Externí odkaz:
https://doaj.org/article/0d21aaf87cc14d6d9a8dfeff34372acf
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::455de778143fba5fbac74ebc18b0f42c
https://doi.org/10.1007/978-1-0716-2643-6_10
https://doi.org/10.1007/978-1-0716-2643-6_10
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2558
The expression of the two isoforms of monoamine oxidase (MAO A and MAO B) is often inferred from proxy measures such as mRNA transcript levels or catalytic activity. Yet the literature is clear that the proportionality of protein, mRNA, and activity
Autor:
Tyler J, Wenzel, Jennifer N K, Nyarko, Ryan M, Heistad, Paul R, Pennington, Chris P, Phenix, Darrell D, Mousseau
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2558
The influence of a protein is not determined exclusively by its level of expression, but also by its localization within the cell. The literature often refers to the enzyme monoamine oxidase (MAO) as a mitochondrial enzyme, yet there is evidence that
Autor:
Cameron J. Morse, Jude S. Morton, Rory A. Marshall, Zeyad El Karsh, Ryan M. Heistad, Robert B. Laprairie, Darrell D. Mousseau, T. Dylan Olver
Publikováno v:
Microvascular Research. :104550
Autor:
Jennifer N. K. Nyarko, Carlos E. de Carvalho, Kaeli J. Knudsen, Paul R. Pennington, Maria A. C. Bolanos, Matthew P. Parsons, Darrell D. Mousseau, Josef Buttigieg, Jocelyn R. Barnes, Ryan M. Heistad, Scot C. Leary, Maa O. Quartey, Jason Maley
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports
Scientific Reports
The pool of β-Amyloid (Aβ) length variants detected in preclinical and clinical Alzheimer disease (AD) samples suggests a diversity of roles for Aβ peptides. We examined how a naturally occurring variant, e.g. Aβ(1–38), interacts with the AD-re
Autor:
Paul R. Pennington, Zelan Wei, Darrell D. Mousseau, Bradley M. Chaharyn, Dennis Bainbridge, Jennifer N. K. Nyarko, Ryan M. Heistad, Glen B. Baker, Maa O. Quartey
Publikováno v:
Biochemical and Biophysical Research Communications. 511:454-459
Biological sex exerts distinct influences on brain levels of the β-amyloid (Aβ) peptide in both clinical depression and Alzheimer disease (AD), yet studies in animal models focus primarily on males. We examined behavioral 'despair'/depression (usin
Autor:
Judes Poirier, Paul R. Pennington, Jennifer N. K. Nyarko, Maa O. Quartey, Doris Dea, Glen B. Baker, Ryan M. Heistad, Darrell D. Mousseau
Publikováno v:
Neuroscience. 373:20-36
The APOE ε4 allele was originally reported to contribute to risk of Alzheimer's disease (AD) in women, yet male and female AD patient-derived data are routinely pooled. Histopathological hallmarks of AD include neurofibrillary tangles centered on hy