Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ryan M. Flessner"'
Publikováno v:
Biomacromolecules. 11:2321-2328
The fungal pathogen Candida albicans can form biofilms on the surfaces of medical devices that are resistant to drug treatment and provide a reservoir for recurrent infections. The use of fungicidal or fungistatic materials to fabricate or coat the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566061d1293fad496bb3f6e7e78f5945
https://doi.org/10.1021/bm100424s
https://doi.org/10.1021/bm100424s
Publikováno v:
Biomacromolecules. 8:857-863
The conjugation of cationic protein transduction domains to proteins results in an increase in the extent to which proteins are internalized by cells. This investigation sought to determine whether the conjugation of a protein transduction domain to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb190f56d6fd5c1125e9aa1172883fe
https://doi.org/10.1021/bm0609442
https://doi.org/10.1021/bm0609442
Autor:
Yongcheng Song, Christine A. Schwerdtfeger, Sarah Odeh, Ermond van Beek, Thomas Kosztowski, Gary A. Meints, Yonghui Zhang, Craig T. Morita, Ryan M. Flessner, Aurora Ortiz Gomez, Eric Oldfield, John M. Sanders, Samuel Jennings, Evangelia Kotsikorou, Hong Wang, Julian M. W. Chan, Amy M. Raker, Socrates E. Papapoulos, Dolores González-Pacanowska
Publikováno v:
Journal of Medicinal Chemistry. 48:2957-2963
We report the design, synthesis and testing of a series of novel bisphosphonates, pyridinium-1-yl-hydroxy-bisphosphonates, based on the results of comparative molecular similarity indices analysis and pharmacophore modeling studies of farnesyl diphos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54bc84d4147b768adea99187cc0fab59
https://doi.org/10.1021/jm040209d
https://doi.org/10.1021/jm040209d
Publikováno v:
Chem. Commun.. 47:550-552
We demonstrate an approach to the assembly of DNA-containing polyelectrolyte multilayers (PEMs) that can be used to promote rapid release of DNA from surfaces. The approach is based on layer-by-layer incorporation of poly(acrylic acid) (PAA) to promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d458c980e4ffdb5e9055761cfbaa2a34
https://doi.org/10.1039/c0cc02926b
https://doi.org/10.1039/c0cc02926b
Publikováno v:
Journal of materials chemistry. 21(6)
We report on the fabrication of covalently crosslinked and amine-reactive hollow microcapsules using ‘reactive’ layer-by-layer assembly to deposit thin polymer films on sacrificial microparticle templates. Our approach is based on the alternating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46411c5b9deed409de53eceb8e6a7aa1
https://pubmed.ncbi.nlm.nih.gov/21383867
https://pubmed.ncbi.nlm.nih.gov/21383867
Autor:
David M. Lynn, Ryan M. Flessner, Eric M. Saurer, Bin Sun, Nathaniel J. Fredin, Christopher M. Jewell
Publikováno v:
Journal of colloid and interface science. 355(2)
We report characterization of pH-dependent behavior in polyelectrolyte multilayers (PEMs) fabricated from poly(allylamine) (PAH) and low molecular weight poly(acrylic acid) (PAA) synthesized by living/controlled polymerization. Exposure of these film
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f350eed1e3d360599e1b10c129fc2b6a
https://pubmed.ncbi.nlm.nih.gov/21237465
https://pubmed.ncbi.nlm.nih.gov/21237465
Publikováno v:
Biomacromolecules. 11(11)
Microneedle patches contain micrometer-scale needles coated with bioactive agents for minimally invasive drug delivery to the skin. In this study, we introduce layer-by-layer approaches to the fabrication of ultrathin DNA- and protein-containing poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc70cd683cd3357b28bcc7948484020
https://pubmed.ncbi.nlm.nih.gov/20942396
https://pubmed.ncbi.nlm.nih.gov/20942396
Autor:
Simon L. Croft, Zev Tovian, Gary A. Meints, Subhash Ghosh, Ryan M. Flessner, Tomoyoshi Nozaki, Eric Oldfield, Robert G. Kemp, Timothy C. Loftus, Julian M. W. Chan, Seike Kobayashi, Christopher R. Lea, Jared C. Lewis, Iris Bruchhaus, Howard Kendrick
Publikováno v:
Journal of medicinal chemistry. 47(1)
The effects of a series of 102 bisphosphonates on the inhibition of growth of Entamoeba histolytica and Plasmodium falciparum in vitro have been determined, and selected compounds were further investigated for their in vivo activity. Forty-seven comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522a7054537b125c2395397276ed3e3a
https://pubmed.ncbi.nlm.nih.gov/14695831
https://pubmed.ncbi.nlm.nih.gov/14695831
Publikováno v:
Langmuir; Jun2011, Vol. 27 Issue 12, p7868-7876, 9p
Publikováno v:
Journal of Materials Chemistry; Jan2011, Vol. 21 Issue 6, p1736-1745, 10p