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Publikováno v:
Organic Letters. 20:1604-1607
A highly regioselective Wacker oxidation has been developed for the oxidation of cinnamyl azides. The catalytic oxidation tolerates the azide functionality, and more than 15 β-azido ketones were isolated (25−92% yield). High regioselectivity for t
Autor:
Anand Divakaran, Jorden A. Johnson, Huarui Cui, Joseph J. Topczewski, Ryan M. Brunner, William C. K. Pomerantz, Angela S. Carlson
Publikováno v:
ACS Med Chem Lett
[Image: see text] The Bromodomain and Extra Terminal (BET) family of proteins recognize post-translational N-ε-acetylated lysine modifications, regulating transcription as “reader” proteins. Bromodomain inhibitors are interesting targets for the