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pro vyhledávání: '"Ryan M Hasselkus"'
Autor:
Anna Herland, Maximilian A. Benz, Olivier Y.F. Henry, Eric V. Shusta, Nur Mustafaoglu, Tae-Eun Park, Alexander L. Watters, Ryan M Hasselkus, Henry Sanchez, Edward A. FitzGerald, Sean P. Palecek, Robert Mannix, Hannah W. Song, Rachelle Prantil-Baun, Liliana Goumnerova, Heather J. McCrea, Donald E. Ingber
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many pharmaceuticals and therapeutic antibodies to the central nervous system. Here, we describe an in vitro microfluidic organ-on-a-chip BBB model lined by induced plu
Autor:
Donald E. Ingber, Heather J. McCrea, Henry Sanchez, Liliana Goumnerova, Anna Herland, Maximilian A. Benz, Olivier Y.F. Henry, Robert Mannix, Ryan M Hasselkus, Edward A. FitzGerald, Nur Mustafaoglu, Sean P. Palecek, Tae-Eun Park, Rachelle Prantil-Baun, Hannah W. Song, Eric V. Shusta, Alexander L. Watters
The highly specialized human brain microvascular endothelium forms a selective blood-brain barrier (BBB) with adjacent pericytes and astrocytes that restricts delivery of many pharmaceuticals and therapeutic antibodies to the central nervous system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c844e17b58a09d2b590b47eb326358