Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ryan Lillico"'
Autor:
Tyson Le, Yuewen Gong, Neal M Davies, Ryan Lillico, Ted Lakowski, Michael S. Roberts, Frank J Burczynski
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1s (2018)
PURPOSE: Liver fatty acid binding protein (FABP1) is a cytoplasmic polypeptide that transports substrates throughout the cytosol and functions as an antioxidant. A common polymorphic variant, FABP1 T94A has a minor allele frequency of 26-38%, 8.3±1.
Externí odkaz:
https://doaj.org/article/9b82d51b77e349788f4e04d211d65b26
Autor:
Babu V. Sajesh, Ngoc H. On, Refaat Omar, Samaa Alrushaid, Brian M. Kopec, Wei-Guang Wang, Han-Dong Sun, Ryan Lillico, Ted M. Lakowski, Teruna J. Siahaan, Neal M. Davies, Pema-Tenzin Puno, Magimairajan Issai Vanan, Donald W. Miller
Publikováno v:
Pharmaceutics, Vol 11, Iss 9, p 481 (2019)
The blood-brain barrier (BBB) poses a major obstacle by preventing potential therapeutic agents from reaching their intended brain targets at sufficient concentrations. While transient disruption of the BBB has been used to enhance chemotherapeutic e
Externí odkaz:
https://doaj.org/article/25cc141381be4297a117030ee6ead52b
Publikováno v:
Pharmaceutics, Vol 10, Iss 1, p 31 (2018)
Creatine is an ergogenic compound used by athletes to enhance performance. Supplementation with creatine monohydrate (CM) has been suggested for musculoskeletal and neurological disorders. Until now, little is known about its pharmacokinetic profile.
Externí odkaz:
https://doaj.org/article/daf71a61cf4a4083817f01d6e633e8bd
Autor:
Júlia T. Novaes, Ryan Lillico, Casey L. Sayre, Kalyanam Nagabushanam, Muhammed Majeed, Yufei Chen, Emmanuel A. Ho, Ana Luísa de P. Oliveira, Stephanie E. Martinez, Samaa Alrushaid, Neal M. Davies, Ted M. Lakowski
Publikováno v:
Pharmaceutics, Vol 9, Iss 4, p 45 (2017)
Tetrahydrocurcumin (THC), curcumin and calebin-A are curcuminoids found in turmeric (Curcuma longa). Curcuminoids have been established to have a variety of pharmacological activities and are used as natural health supplements. The purpose of this st
Externí odkaz:
https://doaj.org/article/2b405f6be5b94c3493e7a516c715b867
Publikováno v:
Pharmaceutics, Vol 9, Iss 3, p 30 (2017)
Despite the lack of safety, efficacy and pharmacokinetic (PK) studies, multicomponent dietary supplements (nutraceuticals) have become increasingly popular as primary or adjunct therapies for clinical osteoarthritis in veterinary medicine. Phycox® i
Externí odkaz:
https://doaj.org/article/f5447d6143db4f5d998091ac68c1ca9b
Autor:
Tina Khorshid Ahmad, Ting Zhou, Khaled AlTaweel, Claudia Cortes, Ryan Lillico, Ted Martin Lakowski, Kiana Gozda, Michael Peter Namaka
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 6, p 1254 (2017)
Multiple sclerosis (MS) is a chronic neurological disease characterized by the destruction of central nervous system (CNS) myelin. At present, there is no cure for MS due to the inability to repair damaged myelin. Although the neurotrophin brain deri
Externí odkaz:
https://doaj.org/article/8d68919a671c4b8ca02400d05cf5e874
Evaluation of cefazolin antimicrobial prophylaxis during cardiac surgery with cardiopulmonary bypass
Autor:
Sheryl A. Zelenitsky, Ted M. Lakowski, Ryan Lillico, Rakesh C. Arora, Robert E. Ariano, Hilary P. Grocott, Divna Calic
Publikováno v:
Journal of Antimicrobial Chemotherapy. 73:768-771
Objectives Although clinical practice guidelines recommend standard cefazolin antimicrobial prophylaxis (AP) dosing for cardiac surgery, limited data exist as to whether adequate concentrations are achieved in this patient population. The goal of our
Autor:
Ryan Lillico, Neal M. Davies, Tyson Le, Yuewen Gong, Michael S. Roberts, Ted M. Lakowski, Frank J. Burczynski
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1s (2018)
PURPOSE: Liver fatty acid binding protein (FABP1) is a cytoplasmic polypeptide that transports substrates throughout the cytosol and functions as an antioxidant. A common polymorphic variant, FABP1 T94A has a minor allele frequency of 26-38%, 8.3±1.
Autor:
Ted M. Lakowski, Robert E. Ariano, Sheryl A. Zelenitsky, Hilary P. Grocott, Ryan Lillico, Rakesh C. Arora, Divna Calic
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
This study characterizes the pharmacodynamics of antimicrobial prophylaxis and sternal wound infections following cardiac surgery. Duration of surgery and cefazolin plasma concentration during wound closure were independently associated with surgical
Autor:
Nicholas Stesco, Ryan Lillico, Tina Khorshid Amhad, Ted M. Lakowski, Claudia Cortes, Mike Namaka
Publikováno v:
Future Medicinal Chemistry. 8:879-897
Gene expression is partly controlled by epigenetic mechanisms including histone-modifying enzymes. Some diseases are caused by changes in gene expression that can be mitigated by inhibiting histone-modifying enzymes. This review covers the enzyme inh