Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ryan LaCanna"'
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Lung alveolar type 2 (AT2) cells are progenitors for alveolar type 1 (AT1) cells. Although many factors regulate AT2 cell plasticity, the role of mitochondrial calcium (mCa2+) uptake in controlling AT2 cells remains unclear. We previously identified
Externí odkaz:
https://doaj.org/article/eed417a3fc8040a19984c2e4436335c9
Autor:
Tongtong Cao, Daniela Liccardo, Ryan LaCanna, Xiaoying Zhang, Rong Lu, Brian N. Finck, Tani Leigh, Xiongwen Chen, Konstantinos Drosatos, Ying Tian
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Cardiomyocyte proliferation accounts for the increase of cardiac muscle during fetal mammalian heart development. Shortly after birth, cardiomyocyte transits from hyperplasia to hypertrophic growth. Here, we have investigated the role of fatty acid
Externí odkaz:
https://doaj.org/article/c5ed965ee7814a6388dd684aced44012
Autor:
Hsiao-Yen Ma, Jason A. Vander Heiden, Salil Uttarwar, Ying Xi, Elsa-Noah N'Diaye, Ryan LaCanna, Patrick Caplazi, Sarah Gierke, John Moffat, Paul J. Wolters, Ning Ding
Publikováno v:
The European respiratory journal.
BackgroundIdiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease characterised by aberrant fibroblast/myofibroblast accumulation and excessive collagen matrix deposition in the alveolar areas of lungs. As the first approved IPF medicat
Autor:
Ying Tian, Peggy Zhang, Marla R. Wolfson, Harold A. Chapman, Beata Kosmider, Edward E. Morrisey, Lauren Tragesser, Yan Wang, Daniela Liccardo, Walter J. Koch, Ryan LaCanna, Tongtong Cao, Hao Shen
Publikováno v:
The Journal of clinical investigation, vol 129, iss 5
Alveolar epithelium plays a pivotal role in protecting the lungs from inhaled infectious agents. Therefore, the regenerative capacity of the alveolar epithelium is critical for recovery from these insults in order to rebuild the epithelial barrier an
Autor:
Paul J. Wolters, Elsa-Noah N’Diaye, Hsiao-Yen Ma, Bushra Husain, Thirumalai R. Ramalingam, Ryan P. Kelly, Alexander Arlantico, Katrina B. Morshead, Si Hyun Kim, Scot A. Marsters, Guiquan Jia, Charles Yu, Claire Emson, Merone Roose-Girma, Daryle Depianto, Ariel E. Feldstein, Lucinda Tam, Ryan LaCanna, Meredith Sagolla, Surinder Jeet, Zhiyu Huang, Hans Brightbill, Jason A. Vander Heiden, Aaron K. Wong, Nadia Martinez Martin, Ying Xi, Patrick Caplazi, Shuang Wu, Laura Lucio, Avi Ashkenazi, Ning Ding, Sarah Gierke
Publikováno v:
SSRN Electronic Journal.
Fibrosis or cirrhosis is the major risk factor associated with morbidity and mortality in patients with non-alcoholic steatohepatitis (NASH)-driven chronic liver disease. While numerous efforts have been made to identify mediators of the initiation o
Autor:
Tulika Tyagi, Elsa-Noah N’Diaye, Robert J. Newman, Hua Wang, Ping Wu, Merone Roose-Girma, Cong Wu, Zhengmao Ye, Paul J. Wolters, Ryan Cook, Dhaya Seshasayee, Wei Yu Lin, Meredith Hazen, Isidro Hötzel, Lucinda Tam, Ryan LaCanna, Ning Ding
Publikováno v:
American journal of physiology. Cell physiology. 320(2)
Proteolytic processing of procollagens is a central step during collagen fibril formation. Bone morphogenic protein 1 (BMP1) is a metalloprotease that plays an important role in the cleavage of carboxy-terminal (COOH-terminal) propeptides from procol
Autor:
Xiongwen Chen, Ying Tian, Xiaoying Zhang, Rong Lu, Tani Leigh, Tongtong Cao, Ryan LaCanna, Daniela Liccardo, Brian N. Finck, Konstantinos Drosatos
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Cardiomyocyte proliferation accounts for the increase of cardiac muscle during fetal mammalian heart development. Shortly after birth, cardiomyocyte transits from hyperplasia to hypertrophic growth. Here, we have investigated the role of fatty acid
Publikováno v:
Circulation Research. 119
In contrast to adult, neonatal cardiomyocytes are able to proliferate and lose this capacity soon after birth when they withdraw from the cell cycle, become binucleated and differentiate. The arrest of cardiomyocytes cell cycle can be reversible for
Autor:
Jeffery C. Powers, Joshua M. Cooper, Christine Varkas, Fabio A. Recchia, Ryan LaCanna, Jeffrey Arkles, Remus M. Berretta, Vickas V. Patel, Jianhe Huang, Mitsuru Seki
Publikováno v:
Journal of the American College of Cardiology. 67:671