Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ryan L Clark"'
Autor:
Susan Hromada, Yili Qian, Tyler B Jacobson, Ryan L Clark, Lauren Watson, Nasia Safdar, Daniel Amador‐Noguez, Ophelia S Venturelli
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 10, Pp 1-19 (2021)
Abstract Understanding the principles of colonization resistance of the gut microbiome to the pathogen Clostridioides difficile will enable the design of defined bacterial therapeutics. We investigate the ecological principles of community resistance
Externí odkaz:
https://doaj.org/article/bd5ffbd93c85490aaac50f95aedc4ea4
Publikováno v:
eLife, Vol 11 (2022)
Predicting the dynamics and functions of microbiomes constructed from the bottom-up is a key challenge in exploiting them to our benefit. Current models based on ecological theory fail to capture complex community behaviors due to higher order intera
Externí odkaz:
https://doaj.org/article/25fdde5e7476427aa4756f294fab0c38
Autor:
Chao Li, Mouhita Humayun, Glenn M. Walker, Keon Young Park, Bryce Connors, Jun Feng, Molly C. Pellitteri Hahn, Cameron O. Scarlett, Jiayi Li, Yanbo Feng, Ryan L. Clark, Hunter Hefti, Jonathan Schrope, Ophelia S. Venturelli, David J. Beebe
Publikováno v:
Advanced Science, Vol 9, Iss 10, Pp n/a-n/a (2022)
Abstract Oxygen levels in vivo are autonomously regulated by a supply–demand balance, which can be altered in disease states. However, the oxygen levels of in vitro cell culture systems, particularly microscale cell culture, are typically dominated
Externí odkaz:
https://doaj.org/article/f25b3aae8abb4f1fb7f387845452b153
Publikováno v:
Western Journal of Emergency Medicine, Vol 21, Iss 3 (2020)
Medicine recognizes burnout as a threat to quality patient care and physician quality of life. This issue exists throughout medicine but is notably prevalent in emergency medicine (EM). Because the concept of “wellness” lacks a clear definition,
Externí odkaz:
https://doaj.org/article/9eab6ed43c9d4899a3b728560d7f74a0
Autor:
David M. Stevenson, Ophelia S. Venturelli, Ryan L. Clark, Bryce Connors, Susan E. Hromada, Joshua J. Hamilton, Daniel Amador-Noguez
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
The capability to design microbiomes with predictable functions would enable new technologies for applications in health, agriculture, and bioprocessing. Towards this goal, we develop a model-guided approach to design synthetic human gut microbiomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2290307df1c5d8d44bfa7359a0cf8b65
https://doaj.org/article/33d2cdec301546449e914c3a28be1c76
https://doaj.org/article/33d2cdec301546449e914c3a28be1c76
Autor:
Bryce M. Connors, Sarah Ertmer, Ryan L. Clark, Jaron Thompson, Brian F. Pfleger, Ophelia S. Venturelli
Microbial communities have tremendous potential as therapeutics. However, a major bottleneck is manufacturing high-diversity microbial communities with desired species compositions. We develop a two-stage, model-guided framework to produce microbial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::852a7640231c3d31c0bc762b29d9a314
https://doi.org/10.1101/2022.03.14.484355
https://doi.org/10.1101/2022.03.14.484355
Publikováno v:
Western Journal of Emergency Medicine
Western Journal of Emergency Medicine, Vol 21, Iss 3 (2020)
Western Journal of Emergency Medicine, Vol 21, Iss 3 (2020)
Medicine recognizes burnout as a threat to quality patient care and physician quality of life. This issue exists throughout medicine but is notably prevalent in emergency medicine (EM). Because the concept of “wellness” lacks a clear definition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218dde75b3f27fcf6b8319cb3c676941
http://europepmc.org/articles/PMC7234720
http://europepmc.org/articles/PMC7234720
Autor:
Chao Li, Mouhita Humayun, Glenn M. Walker, Keon Young Park, Bryce Connors, Jun Feng, Molly C. Pellitteri Hahn, Cameron O. Scarlett, Jiayi Li, Yanbo Feng, Ryan L. Clark, Hunter Hefti, Jonathan Schrope, Ophelia S. Venturelli, David J. Beebe
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(10)
Oxygen levels in vivo are autonomously regulated by a supply-demand balance, which can be altered in disease states. However, the oxygen levels of in vitro cell culture systems, particularly microscale cell culture, are typically dominated by either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4926624a9a6eab77b7d360109e1dad6d
https://pubmed.ncbi.nlm.nih.gov/35118834
https://pubmed.ncbi.nlm.nih.gov/35118834
Autor:
Nasia Safdar, Tyler B. Jacobson, Susan E. Hromada, Yili Qian, Ophelia S. Venturelli, Ryan L. Clark, Lauren Watson, Daniel Amador-Noguez
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 10, Pp n/a-n/a (2021)
Molecular Systems Biology
Molecular Systems Biology
Understanding the principles of colonization resistance of the gut microbiome to the pathogen Clostridioides difficile will enable the design of defined bacterial therapeutics. We investigate the ecological principles of community resistance to C. di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f8e2f029c00abbcae42ca56199ab56
https://doi.org/10.15252/msb.202110355
https://doi.org/10.15252/msb.202110355