Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ryan K, Spangler"'
Autor:
Christopher J Skalnik, Sean Y Cheah, Mica Y Yang, Mattheus B Wolff, Ryan K Spangler, Lee Talman, Jerry H Morrison, Shayn M Peirce, Eran Agmon, Markus W Covert
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1011232 (2023)
Antibiotic resistance poses mounting risks to human health, as current antibiotics are losing efficacy against increasingly resistant pathogenic bacteria. Of particular concern is the emergence of multidrug-resistant strains, which has been rapid amo
Externí odkaz:
https://doaj.org/article/c586e70966d047e2adda5d4777ce5255
Autor:
Eran Agmon, Ryan K. Spangler
Publikováno v:
Entropy, Vol 22, Iss 10, p 1101 (2020)
The degree to which we can understand the multi-scale organization of cellular life is tied to how well our models can represent this organization and the processes that drive its evolution. This paper uses Vivarium—an engine for composing heteroge
Externí odkaz:
https://doaj.org/article/b8c74ddbbf184e169009491e472ede7b
Autor:
Markus W. Covert, Christopher J Skalnik, Shayn M. Peirce, Morrison Jh, William Poole, Ryan K. Spangler, Eran Agmon
Publikováno v:
Bioinformatics
Motivation This article introduces Vivarium—software born of the idea that it should be as easy as possible for computational biologists to define any imaginable mechanistic model, combine it with existing models and execute them together as an int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b780e92d557516919ee6fb85ca74ea4d
https://europepmc.org/articles/PMC8963310/
https://europepmc.org/articles/PMC8963310/
Autor:
Lee Talman, Eran Agmon, Christopher J Skalnik, Shayn M. Peirce, Morrison Jh, Markus W. Covert, Ryan K. Spangler
Bacterial behavior is the outcome of both molecular mechanisms within each cell and interactions between cells in the context of their environment. Whereas whole-cell models simulate a single cell’s behavior using molecular mechanisms, agent-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40340f811e8d6fe5b8af8054ee8be730
https://doi.org/10.1101/2021.04.27.441666
https://doi.org/10.1101/2021.04.27.441666
Autor:
Ryan K. Spangler, Eran Agmon
Publikováno v:
Entropy, Vol 22, Iss 1101, p 1101 (2020)
Entropy
Volume 22
Issue 10
Entropy
Volume 22
Issue 10
The degree to which we can understand the multi-scale organization of cellular life is tiedto how well our models can represent this organization and the processes that drive its evolution.This paper uses Vivarium&mdash
an engine for composing h
an engine for composing h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c893a8de7db2e680c59f3a8615e7bd
https://www.mdpi.com/1099-4300/22/10/1101
https://www.mdpi.com/1099-4300/22/10/1101
Autor:
Peter D. Karp, Inbal Maayan, Gwanggyu Sun, Sajia Akhter, Taryn E. Gillies, Daniel Weaver, Heejo Choi, Jerry H. Morrison, Samuel R. Bray, Ingrid M. Keseler, Morgan L. Paull, Ryan K. Spangler, Travis A. Ahn-Horst, Markus W. Covert, Nicholas A. Ruggero, Mialy M. DeFelice, John C. Mason, Javier Carrera, Derek N. Macklin, Keara Michelle Lane, Eran Agmon
Publikováno v:
Science. 369:eaav3751
The extensive heterogeneity of biological data poses challenges to analysis and interpretation. Construction of a large-scale mechanistic model of Escherichia coli enabled us to integrate and cross-evaluate a massive, heterogeneous dataset based on m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94b08b6985d35dcd7c31c99e05c62ffb
https://doi.org/10.1126/science.aav3751
https://doi.org/10.1126/science.aav3751
Autor:
Derek N, Macklin, Travis A, Ahn-Horst, Heejo, Choi, Nicholas A, Ruggero, Javier, Carrera, John C, Mason, Gwanggyu, Sun, Eran, Agmon, Mialy M, DeFelice, Inbal, Maayan, Keara, Lane, Ryan K, Spangler, Taryn E, Gillies, Morgan L, Paull, Sajia, Akhter, Samuel R, Bray, Daniel S, Weaver, Ingrid M, Keseler, Peter D, Karp, Jerry H, Morrison, Markus W, Covert
Publikováno v:
Science (New York, N.Y.). 369(6502)
The extensive heterogeneity of biological data poses challenges to analysis and interpretation. Construction of a large-scale mechanistic model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9276b425197d6724fbd306f575e1a3a3
https://pubmed.ncbi.nlm.nih.gov/32994565
https://pubmed.ncbi.nlm.nih.gov/32994565