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pro vyhledávání: '"Ryan Jordanhazy"'
Autor:
Jean S. Oak, Rosemarie H. DeKruyff, Anjali J. de Souza, Lawrence P. Kane, Ryan Jordanhazy, David A. Fruman
Publikováno v:
The Journal of Immunology. 180:6518-6526
Ligation of the transmembrane protein T cell Ig and mucin domain (Tim)-1 can costimulate T cell activation. Agonistic Abs to Tim-1 are also capable of inducing T cell activation without additional stimuli. However, little is known about the biochemic
Publikováno v:
The Journal of Immunology. 178:S127-S128
Bcl10 is a component of the “CBM” complex of proteins, along with CARMA and MALT1. This complex regulates activation of the NF-κB-inducing IKK kinase complex, and is important for integrating signals from antigen receptors and co-receptors on T