Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ryan J.O. Dowling"'
Autor:
Melinda L. Irwin, Rinath Jeselsohn, Eric P. Winer, Myles Brown, Ying Huang, Krishan Taneja, Esther Rhei, Mehra Golshan, Laura S. Dominici, Rachel A. Freedman, Rachel L. Yung, Anees B. Chagpar, Sara Tolaney, Martin C. Chang, Ryan J.O. Dowling, Nancy Campbell, Matthew Pun, MacIntosh Cornwell, Elizabeth Frank, Anne McTiernan, Anita Giobbie-Hurder, Deborah Dillon, Jennifer A. Ligibel
Supplemental Figure 1: Study Schema Supplemental Table 1: Tissue Insulin Receptor Staining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a30063df2013f2973b0746ad3cb20fa
https://doi.org/10.1158/1078-0432.22471742
https://doi.org/10.1158/1078-0432.22471742
Autor:
Melinda L. Irwin, Rinath Jeselsohn, Eric P. Winer, Myles Brown, Ying Huang, Krishan Taneja, Esther Rhei, Mehra Golshan, Laura S. Dominici, Rachel A. Freedman, Rachel L. Yung, Anees B. Chagpar, Sara Tolaney, Martin C. Chang, Ryan J.O. Dowling, Nancy Campbell, Matthew Pun, MacIntosh Cornwell, Elizabeth Frank, Anne McTiernan, Anita Giobbie-Hurder, Deborah Dillon, Jennifer A. Ligibel
Purpose:Exercise after breast cancer diagnosis is associated with lower cancer-specific mortality, but the biological mechanisms through which exercise impacts breast cancer are not fully understood. The Pre-Operative Health and Body (PreHAB) Study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284501ecba6186448d267e661c389455
https://doi.org/10.1158/1078-0432.c.6527990.v1
https://doi.org/10.1158/1078-0432.c.6527990.v1
Autor:
Vuk Stambolic, Karina Bukhanov, Ryan J.O. Dowling, Marguerite Ennis, Jaime Escallon, Pamela J. Goodwin, Martin C. Chang
Publikováno v:
Cancer Research. 81:PS18-25
Background and Rationale: Biomarker evaluation on breast tumor tissue is an important component of clinical research. There is a concern that tissues collected at different times (pre- vs intra-op) and with different techniques (core biopsy vs. surgi
Autor:
Deborah A. Dillon, Sara M. Tolaney, Matthew Pun, Eric P. Winer, Esther Rhei, Melinda L. Irwin, Rachel A. Freedman, Elizabeth S. Frank, Anita Giobbie-Hurder, Krishan Taneja, Ryan J.O. Dowling, Laura S. Dominici, Myles Brown, Nancy Campbell, Jennifer A. Ligibel, Rinath Jeselsohn, Anne McTiernan, Ying Huang, Rachel L. Yung, MacIntosh Cornwell, Mehra Golshan, Martin C. Chang, Anees B. Chagpar
Publikováno v:
Clinical Cancer Research. 25:5398-5406
Purpose: Exercise after breast cancer diagnosis is associated with lower cancer-specific mortality, but the biological mechanisms through which exercise impacts breast cancer are not fully understood. The Pre-Operative Health and Body (PreHAB) Study
Autor:
Ryan J.O. Dowling, Vuk Stambolic
Publikováno v:
JNCI cancer spectrum. 4(1)
Autor:
Daniel Schramek, Funda Meric-Bernstam, Daniel F. Hayes, Wendy R. Parulekar, Ana Elisa Lohmann, Larissa A. Korde, Timothy J. Whelan, Marguerite Ennis, Vuk Stambolic, Jane Perlmutter, N. Lynn Henry, Pamela J. Goodwin, James R. Woodgett, Joseph O. Deasy, Mitch Dowsett, Martin C. Chang, Robert Gray, Eleftherios P. Mamounas, Sarat Chandarlapaty, George W. Sledge, Joseph A. Sparano, Scott V. Bratman, Angela DeMichele, Katarzyna J. Jerzak, Meredith M. Regan, Kevin Kalinsky, Antonio C. Wolff, Ryan J.O. Dowling, Mangesh A. Thorat, François-Clément Bidard, Lisa A. Carey, David W. Cescon
Publikováno v:
JNCI Cancer Spectrum
Late disease recurrence (more than 5 years after initial diagnosis) represents a clinical challenge in the treatment and management of estrogen receptor-positive breast cancer (BC). An international workshop was convened in Toronto, Canada, in Februa
Autor:
CM Hamm, Pamela J. Goodwin, Rashida Haq, David Cescon, Isabel Pimentel, K.R. Potvin, Martin C. Chang, Marguerite Ennis, Ryan J.O. Dowling, Vuk Stambolic, Ana Elisa Lohmann, Christine Elser
Publikováno v:
Breast (Edinburgh, Scotland). 48
Objectives Pre-clinical data suggest metformin might enhance the effect of chemotherapy in breast cancer (BC). We conducted a Phase II randomized trial of chemotherapy plus metformin versus placebo in metastatic breast cancer (MBC). Material and meth
Autor:
David W. Cescon, Daniel Schramek, Kevin Kalinsky, Robert Gray, Daniel F. Hayes, Marguerite Ennis, Ana Elisa Lohmann, Scott V. Bratman, N. Lynn Henry, Timothy J. Whelan, Lisa A. Carey, Angela DeMichele, Katarzyna J. Jerzak, Vuk Stambolic, Mangesh A. Thorat, Joseph A. Sparano, Meredith M. Regan, François-Clément Bidard, Mitch Dowsett, Jane Perlmutter, Joseph O. Deasy, Wendy R. Parulekar, Larissa A. Korde, Martin C. Chang, James R. Woodgett, Antonio C. Wolff, Ryan J.O. Dowling, Funda Meric-Bernstam, George W. Sledge, Pamela J. Goodwin, Eleftherios P. Mamounas, Sarat Chandarlapaty
Publikováno v:
JNCI Cancer Spectrum
Disease recurrence (locoregional, distant) exerts a significant clinical impact on the survival of estrogen receptor–positive breast cancer patients. Many of these recurrences occur late, more than 5 years after original diagnosis, and represent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1013058172c7ff7804d39deeda0f0a
Autor:
Pamela J. Goodwin, Elma Lee, Marguerite Ennis, Kamran Fazaee, Eitan Amir, Ana Elisa Lohmann, Christine Elser, Vuk Stambolic, Ryan J.O. Dowling, Christine Brezden-Masley, Martin C. Chang, Theodore A. Vandenberg
Publikováno v:
Jnci Cancer Spectrum
Background Circulating tumor cells (CTCs) are associated with worse prognosis in metastatic breast cancer (BC). We evaluated the association of metabolic, inflammatory, and tumor markers with CTCs in women with metastatic BC before commencing a new s
Autor:
Ryan J.O. Dowling, Lee B. Jordan, Colin A. Purdie, Pamela J. Goodwin, Susan J. Done, Martin C. Chang, Vuk Stambolic, Stacy Moulder-Thompson, Philip J. Coates, Alastair M. Thompson, Sirwan Hadad
Publikováno v:
Breast Cancer Research and Treatment. 150:149-155
Metformin has therapeutic potential against breast cancer, but the mechanisms of action in vivo remain uncertain. This study examined biomarker effects of metformin in primary breast cancer in a preoperative window of opportunity trial. Non-diabetic