Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ryan J. Whitmarsh"'
Autor:
Christopher A. Hunter, Kenneth H. Hu, Ryan J. Whitmarsh, Kirk D. C. Jensen, Lindsay Julien, Jeroen P. J. Saeij, Lieping Chen, Musa A. Hassan, Diana Lu
Publikováno v:
Infection and immunity. 81(6)
Toxoplasma gondii transmission between intermediate hosts is dependent on the ingestion of walled cysts formed during the chronic phase of infection. Immediately following consumption, the parasite must ensure survival of the host by preventing adver
Autor:
Lucas D. Tilley, Gary E. Ward, Ryan J. Whitmarsh, Christopher A. Hunter, Whittney Barkhuff, Stacey D. Gilk
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 8, p e23977 (2011)
PLoS ONE, Vol 6, Iss 8, p e23977 (2011)
The inner membrane complex (IMC), a series of flattened vesicles at the periphery of apicomplexan parasites, is thought to be important for parasite shape, motility and replication, but few of the IMC proteins that function in these processes have be
Autor:
Carolyn A. Felix, Neil Osheroff, Nicholas C.P. Cross, Bruno Cassinat, David Grimwade, Ryan J. Whitmarsh, Lionel Ades, Ian A. Blair, A Parry, Andrew Peniket, Annabel Mason, Marina Lafage-Pochitaloff, Joseph L. Wiemels, Pierre Fenaux, Andreas Reiter, Anita R. Mistry, Mark R. Segal, Christoph Walz, Ellen Solomon, Christine Chomienne
Publikováno v:
The New England journal of medicine. 352(15)
Chromosomal translocations leading to chimeric oncoproteins are important in leukemogenesis, but how they form is unclear. We studied acute promyelocytic leukemia (APL) with the t(15;17) translocation that developed after treatment of breast or laryn
Autor:
Diana J. Slater, Charles Saginario, Ian A. Blair, Neil Osheroff, Eric F. Rappaport, Maureen D. Megonigal, Eva Hilgenfeld, Carolyn A. Felix, Ryan J. Whitmarsh, Mingli Liu, Thomas Ried, Turid Knutsen, Nai-Kong V. Cheung, Martin Carroll, Ya Zhuo
Publikováno v:
Oncogene. 22(52)
Few t(9;11) translocations in DNA topoisomerase II inhibitor-related leukemias have been studied in detail and the DNA damage mechanism remains controversial. We characterized the der(11) and der(9) genomic breakpoint junctions in a case of AML follo
Autor:
David A. Christian, Christopher A. Hunter, Michael J. May, Carolyn M. Gray, Beth Gregg, Ryan J. Whitmarsh, Peter J. Murray
Publikováno v:
Cell Host & Microbe. (3):224-236
SummaryThe innate and adaptive immune responses that confer resistance to the intracellular pathogen Toxoplasma gondii critically depend on IL-12 production, which drives interferon-γ (IFN-γ) expression. Certain cytokines can activate STAT3 and lim
Publikováno v:
Cell Host & Microbe. (5):413-414
Autophagy provides a mechanism for cells to conserve nutrients, but was recently associated with immunity to intracellular pathogens. Here, Zhao et al. (2008) present direct in vivo evidence that autophagy is linked to macrophage control of Toxoplasm