Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ryan J. O. Dowling"'
Autor:
Pamela J. Goodwin, Ryan J. O. Dowling, Marguerite Ennis, Bingshu E. Chen, Wendy R. Parulekar, Lois E. Shepherd, Margot J. Burnell, Rachel Vander Meer, Andrea Molckovsky, Anagha Gurjal, Karen A. Gelmon, Jennifer A. Ligibel, Dawn L. Hershman, Ingrid A. Mayer, Timothy J. Whelan, Timothy J. Hobday, Priya Rastogi, Manuela Rabaglio-Poretti, Julie Lemieux, Alastair M. Thompson, Daniel W. Rea, Vuk Stambolic
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Metformin may exert anticancer effects through indirect (mediated by metabolic changes) or direct mechanisms. The goal was to examine metformin impact on metabolic factors in non-diabetic subjects and determine whether this impact varies by
Externí odkaz:
https://doaj.org/article/ed8c22cdd63b4d8ab3a69bbf18ba9909
Autor:
Daniel Rea, Marguerite Ennis, Vuk Stambolic, Timothy J. Hobday, Ingrid A. Mayer, Manuela Rabaglio-Poretti, Julie Lemieux, Anagha Gurjal, Bingshu E. Chen, Rachel Vander Meer, Andrea Molckovsky, Dawn L. Hershman, Karen A. Gelmon, Timothy J. Whelan, Margot J. Burnell, Priya Rastogi, Jennifer A. Ligibel, Ryan J. O. Dowling, Alastair M. Thompson, Pamela J. Goodwin, Wendy R. Parulekar, Lois E. Shepherd
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
NPJ Breast Cancer
NPJ Breast Cancer
Metformin may exert anticancer effects through indirect (mediated by metabolic changes) or direct mechanisms. The goal was to examine metformin impact on metabolic factors in non-diabetic subjects and determine whether this impact varies by baseline
Autor:
Priya Rastogi, Pamela J. Goodwin, Daniel Rea, Ryan J. O. Dowling, Wendy R. Parulekar, Alastair M. Thompson, Vuk Stambolic, Karen A. Gelmon, Marguerite Ennis, Manuela Rabaglio-Poretti, Timothy J. Hobday, Lois E. Shepherd, Ingrid A. Mayer, Jennifer A. Ligibel, Bingshu E. Chen, Dawn L. Hershman, Timothy J. Whelan, Julie Lemieux
Publikováno v:
JNCI Cancer Spectrum
Background Circulating levels of cancer antigen (CA) 15–3, a tumor marker and regulator of cellular metabolism, were reduced by metformin in a nonrandomized neoadjuvant study. We examined the effects of metformin (vs placebo) on CA 15–3 in partic