Výsledky vyhledávání - "Ryan J. Morrison"

Regio‐ and Enantioselective Synthesis of Trifluoromethyl‐Substituted Homoallylic α‐Tertiary NH 2 ‐Amines by Reactions Facilitated by a Threonine‐Based Boron‐Containing Catalyst

Autor: Amir H. Hoveyda, Ryan J. Morrison, Diana C. Fager

Publikováno v: Angewandte Chemie International Edition. 59:11448-11455

A method for catalytic regio- and enantioselective synthesis of trifluoromethyl-substituted and aryl-, heteroaryl-, alkenyl-, and alkynyl-substituted homoallylic α-tertiary NH2 -amines is introduced. Easy-to-synthesize and robust N-silyl ketimines a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f403e9ed8af29ec0518769442309fb0
https://doi.org/10.1002/anie.202001184

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A Catalytic Approach for Enantioselective Synthesis of Homoallylic Alcohols Bearing a Z-Alkenyl Chloride or Trifluoromethyl Group. A Concise and Protecting Group-Free Synthesis of Mycothiazole

Autor: Filippo Romiti, Farid W. van der Mei, Ryan J. Morrison, Amir H. Hoveyda

Publikováno v: J Am Chem Soc

A protecting group-free strategy is presented for diastereo- and enantioselective routes that can be used to prepare a wide variety of Z-homoallylic alcohols with significantly higher efficiency than is otherwise feasible. The approach entails the me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b67516555f755f2acec021c6279bf3
https://doi.org/10.1021/jacs.9b11178

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Diastereo- and enantioselective synthesis of compounds with a trifluoromethyl- and fluoro-substituted carbon centre

Autor: Shibo Xu, Juan del Pozo, Filippo Romiti, Yue Fu, Binh Khanh Mai, Ryan J. Morrison, KyungA Lee, Shaowei Hu, Ming Joo Koh, Jaehee Lee, Xinghan Li, Peng Liu, Amir H. Hoveyda

Publikováno v: Nature chemistry.

Molecules that contain one or more fluorine atoms are crucial to drug discovery. There are protocols available for the selective synthesis of different organofluorine compounds, including those with a fluoro-substituted or a trifluoromethyl-substitut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb43749fc7f1f0db0cd2566601509a7
https://pubmed.ncbi.nlm.nih.gov/36376387

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Regio- and Enantioselective Synthesis of Trifluoromethyl-Substituted Homoallylic α-Tertiary NH

Autor: Diana C, Fager, Ryan J, Morrison, Amir H, Hoveyda

Publikováno v: Angew Chem Int Ed Engl

A method for catalytic regio- and enantioselective synthesis of trifluoromethyl-substituted and aryl-, heteroaryl-, alkenyl-, and alkynyl-substituted homoallylic α-tertiary NH(2)-amines is introduced. Easy- to-synthesize and robust N-silyl ketimines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7ca13fcfd23da3ee91d539ad74bd34c
https://pubmed.ncbi.nlm.nih.gov/32219997

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γ‐, Diastereo‐, and Enantioselective Addition of MEMO‐Substituted Allylboron Compounds to Aldimines Catalyzed by Organoboron–Ammonium Complexes

Autor: Ryan J. Morrison, Amir H. Hoveyda

Publikováno v: Angewandte Chemie International Edition. 57:11654-11661

The first catalytic, broadly applicable, efficient, γ-, diastereo-, and enantioselective method for addition of O-substituted allyl–B(pin) compounds to phosphinoylimines (MEM = methoxyethoxymethyl, pin = pinacolato) is presented. The identity of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee8a1c07b01a49d23b0cf2a82931eb4
https://doi.org/10.1002/anie.201805811

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Practical, Broadly Applicable, α-Selective, Z-Selective, Diastereoselective and Enantioselective Addition of Allylboron Compounds to Mono-, Di-, Tri- and Polyfluoroalkyl Ketones

Autor: Ryan J. Morrison, Farid W. van der Mei, Amir H. Hoveyda, Changming Qin

A practical method for enantioselective synthesis of fluoroalkyl-substituted Z-homoallylic tertiary alcohols has been developed. Reactions may be performed with ketones containing a polylfluoro-, trifluoro-, difluoro- and monofluoroalkyl group along

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddcc73854da969af25705b80b24a26b1
https://europepmc.org/articles/PMC5551497/

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The Shifting Landscape of Global Internet Censorship

Autor: Helmi Noman, Ryan J. Morrison-Westphal, Jonathan L. Zittrain, Casey Tilton, Justin Clark, Robert Faris

Publikováno v: SSRN Electronic Journal.

A sharp increase in web encryption and a worldwide shift away from standalone websites in favor of social media and online publishing platforms has altered the practice of state-level Internet censorship and in some cases led to broader crackdowns, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::617a82b9b1f1d91eb2e481a3bd6c8032
https://doi.org/10.2139/ssrn.2993485

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