Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ryan J. Li"'
Autor:
Kenneth R. Gundle, Karthik Rajasekaran, Jeffrey Houlton, Gary B. Deutsch, Thomas J. Ow, Robert G. Maki, John Pang, Cherie-Ann O. Nathan, Daniel Clayburgh, Jason G. Newman, Elyse Brinkmann, Michael J. Wagner, Seth M. Pollack, Matthew J. Thompson, Ryan J. Li, Vikas Mehta, Bradley A. Schiff, Barry I. Wenig, Paul L. Swiecicki, Alice L. Tang, Jessica L. Davis, Annemieke van Zante, Jessica A. Bertout, Wendy Jenkins, Atticus Turner, Marc Grenley, Connor Burns, Jason P. Frazier, Angela Merrell, Kimberly H. W. Sottero, Jonathan M. J. Derry, Kate C. Gillespie, Bre Mills, Richard A. Klinghoffer
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Drug development is systemically inefficient. Research and development costs for novel therapeutics average hundreds of millions to billions of dollars, with the overall likelihood of approval estimated to be as low as 6.7% for oncology
Externí odkaz:
https://doaj.org/article/df356ddd88154387999a5c867f337370
Autor:
Daria A Gaykalova, Elizabeth Mambo, Ashish Choudhary, Jeffery Houghton, Kalyan Buddavarapu, Tiffany Sanford, Will Darden, Alex Adai, Andrew Hadd, Gary Latham, Ludmila V Danilova, Justin Bishop, Ryan J Li, William H Westra, Patrick Hennessey, Wayne M Koch, Michael F Ochs, Joseph A Califano, Wenyue Sun
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233409 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0093102.].
Externí odkaz:
https://doaj.org/article/8c1619d622f047fbb4102119ccdb2917
Autor:
Vivek C. Pandrangi, Suparna N. Shah, Jennifer D. Bruening, Mark K. Wax, Daniel Clayburgh, Peter E. Andersen, Ryan J. Li
Publikováno v:
JAMA Otolaryngol Head Neck Surg
ImportanceOptimal postoperative pain management is challenging. Virtual reality (VR) provides immersive, 3-dimensional experiences that may improve pain control and reduce reliance on pharmacologic pain management.ObjectiveTo evaluate use of VR on po
Autor:
Carole Fakhry, Nishant Agrawal, Joseph Califano, Wayne Koch, David Sidransky, Evgeny Izumchenko, Rachel Karchin, Christopher Douville, Ryan J. Li, Rajni Sharma, Jason D. Howard, Justin A. Bishop, Christine H. Chung, Eleni M. Rettig
The Notch pathway is frequently altered in head and neck squamous cell carcinomas (HNSCC); however, the clinical significance of NOTCH1 dysregulation is poorly understood. This study was designed to characterize expression of the transcriptionally ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c2305fd5965c676b75659525433dc2
https://doi.org/10.1158/1940-6207.c.6544991.v1
https://doi.org/10.1158/1940-6207.c.6544991.v1
Autor:
Carole Fakhry, Nishant Agrawal, Joseph Califano, Wayne Koch, David Sidransky, Evgeny Izumchenko, Rachel Karchin, Christopher Douville, Ryan J. Li, Rajni Sharma, Jason D. Howard, Justin A. Bishop, Christine H. Chung, Eleni M. Rettig
Supplementary Table 1. Clinicopathological characteristics of tumors with NICD1 IHC available compared with unavailable.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73281821e194bd558f49f0dede66cdfa
https://doi.org/10.1158/1940-6207.22526060
https://doi.org/10.1158/1940-6207.22526060
Autor:
Vivek C. Pandrangi, Matthew Jorizzo, Suparna Shah, Jennifer Bruening, Mark K. Wax, Daniel Clayburgh, Peter Andersen, Ryan J. Li
Publikováno v:
HeadneckREFERENCES. 44(12)
To evaluate use of wearable activity devices to monitor trends in ambulation and sleep after head and neck surgery.Patients utilized Fitbit devices after surgery. Daily activity and sleep scores, step counts, and total sleep time (TST) were obtained.
Autor:
Glenn J. Hanna, N. M. Krishnan, Krystle A. Lang Kuhs, Benjamin R. Campbell, Daniel L. Faden, André Luiz Vettore, Ryan J. Li, Jeffrey N. Myers, Curtis R. Pickering, Binay Panda, Nishant Agrawal, Steven G. Rozen, Xingyi Guo, N. Gopalakrishna Iyer, Zhishan Chen, Arnoud Boot
Publikováno v:
Cancer
Background The incidence of oral tongue squamous cell carcinoma (OTSCC) is increasing among younger birth cohorts. The etiology of early-onset OTSCC (diagnosed before the age of 50 years) and cancer driver genes remain largely unknown. Methods The Se
Publikováno v:
Multidisciplinary Management of Head and Neck Cancer ISBN: 9783031059728
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bf0b37e7ae965d88a490ac9f3dee1ba
https://doi.org/10.1007/978-3-031-05973-5_2
https://doi.org/10.1007/978-3-031-05973-5_2
Autor:
Karthik Rajasekaran, Jason G. Newman, Robert G. Maki, Thomas J. Ow, Vikas Mehta, Kenneth R. Gundle, Daniel R. Clayburgh, Ryan J. Li, Mercedes Porosnicu, Cherie-Ann O. Nathan, Alice Tang, Beryl A. Hatton, Kimberly H. Sottero, Gloria Kung, Marc O. Grenley, Kirsten Anderson, Richard A. Klinghoffer
Publikováno v:
Cancer Research. 82:CT216-CT216
Purpose/Objectives: Tumor responses to cancer treatments are highly context-specific and often involve complex interactions between the anti-cancer therapy, genetically diverse tumor cells, and a heterogeneous tumor microenvironment (TME). All precli
Autor:
Jeffrey Houlton, Harrison Cash, Haodong Xu, Paul L. Swiecicki, Keith Casper, Steven B. Chinn, Daniel R. Clayburgh, Ryan J. Li, Robert J. Christian, Aaron Halfpenny, Annemieke van Zante, Beryl A. Hatton, Kimberly Sottero, Marc O. Grenley, Connor Burns, Jason Frazier, Jonathan Derry, Gloria Kung, Emily Beirne, Nathan J. Schauer, Atticus Turner, Wendy Jenkins, Kirsten Anderson, Richard A. Klinghoffer, Dennis Huszar, Allison Berger, Karuppiah Kannan
Publikováno v:
Cancer Research. 82:CT139-CT139
Purpose/Objectives: The human tumor microenvironment (TME) has a dramatic impact on cancer prognosis and therapeutic response, but accurate models of the native TME do not exist. The Comparative In Vivo Oncology (CIVO) platform was developed as a mea