Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ryan J. Kast"'
Publikováno v:
eLife, Vol 8 (2019)
The expression patterns of the transcription factor FOXP2 in the developing mammalian forebrain have been described, and some studies have tested the role of this protein in the development and function of specific forebrain circuits by diverse metho
Externí odkaz:
https://doaj.org/article/ac19d9b8943048cb9fdf66d43934f169
Autor:
Jennifer I Park, Michael G Frantz, Ryan J Kast, Katherine S Chapman, Hilary M Dorton, Céleste-Élise Stephany, Megan T Arnett, David H Herman, Aaron W McGee
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112678 (2014)
The genes that govern how experience refines neural circuitry and alters synaptic structural plasticity are poorly understood. The nogo-66 receptor 1 gene (ngr1) is one candidate that may restrict the rate of learning as well as basal anatomical plas
Externí odkaz:
https://doaj.org/article/c793e79d332a4c2d8e0d609986c79886
Publikováno v:
ACS Chemical Neuroscience. 8:1053-1064
Molecular characterization of neurons across brain regions has revealed new taxonomies for understanding functional diversity even among classically defined neuronal populations. Neuronal diversity has become evident within the brain serotonin (5-HT)
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
The expression patterns of the transcription factor FOXP2 in the developing mammalian forebrain have been described, and some studies have tested the role of this protein in the development and function of specific forebrain circuits by diverse metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e14fbd8d3970f83a12101eb320fad59
https://doi.org/10.1101/617852
https://doi.org/10.1101/617852
Autor:
Ryan J. Kast, Pat Levitt
Of all brain regions, the 6-layered neocortex has undergone the most dramatic changes in size and complexity during mammalian brain evolution. These changes, occurring in the context of a conserved set of organizational features that emerge through s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cbe007d35320d364fe1397100fb03b
https://europepmc.org/articles/PMC6402587/
https://europepmc.org/articles/PMC6402587/
The complex circuitry and cell-type diversity of the cerebral cortex are required for its high-level functions. The mechanisms underlying the diversification of cortical neurons during prenatal development have received substantial attention, but und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2c40a43322fd230bfce8110aef4fc8
https://europepmc.org/articles/PMC6294411/
https://europepmc.org/articles/PMC6294411/
The formation and stability of dendritic spines on excitatory cortical neurons are correlated with adult visual plasticity, yet how the formation, loss, and stability of postsynaptic spines register with that of presynaptic axonal varicosities is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff7ffce442bc440aa3ffc903381bff4
https://europepmc.org/articles/PMC4830283/
https://europepmc.org/articles/PMC4830283/
Publikováno v:
Brain, behavior, and immunity. 30
Increasing evidence suggests that maternal infection increases the risk of psychiatric disorders, such as schizophrenia and autism in offspring. However, the molecular mechanisms associated with these effects are unclear. Here, we have studied epigen
Publikováno v:
Human molecular genetics. 21(24)
We previously demonstrated that the histone deacetylase (HDAC) inhibitor, 4b, which preferentially targets HDAC1 and HDAC3, ameliorates Huntington's disease (HD)-related phenotypes in different HD model systems. In the current study, we investigated