Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ryan J. Farr"'
Autor:
Andrzej S. Januszewski, Yoon Hi Cho, Mugdha V. Joglekar, Ryan J. Farr, Emma S. Scott, Wilson K. M. Wong, Luke M. Carroll, Yik W. Loh, Paul Z. Benitez-Aguirre, Anthony C. Keech, David N. O’Neal, Maria E. Craig, Anandwardhan A. Hardikar, Kim C. Donaghue, Alicia J. Jenkins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The aim of this cross-sectional study was to compare plasma C-peptide presence and levels in people without diabetes (CON) and with Type 1 diabetes and relate C-peptide status to clinical factors. In a subset we evaluated 50 microRNAs (miRs)
Externí odkaz:
https://doaj.org/article/b1ec56fdb12a4c0cb5cb32be78d2f006
Autor:
Mugdha V. Joglekar, Subhshri Sahu, Wilson K.M. Wong, Sarang N. Satoor, Charlotte X. Dong, Ryan J. Farr, Michael D. Williams, Prapti Pandya, Gaurang Jhala, Sundy N.Y. Yang, Yi Vee Chew, Nicola Hetherington, Dhan Thiruchevlam, Sasikala Mitnala, Guduru V. Rao, Duvvuru Nageshwar Reddy, Thomas Loudovaris, Wayne J. Hawthorne, Andrew G. Elefanty, Vinay M. Joglekar, Edouard G. Stanley, David Martin, Helen E. Thomas, David Tosh, Louise T. Dalgaard, Anandwardhan A. Hardikar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1530-1553.e4 (2022)
Background & Aims: Pancreatic islet β-cells are factories for insulin production; however, ectopic expression of insulin also is well recognized. The gallbladder is a next-door neighbor to the developing pancreas. Here, we wanted to understand if ga
Externí odkaz:
https://doaj.org/article/3d728a223a8941f1b6deb7467c5a4e8a
Autor:
Ryan J. Farr, Nathan Godde, Christopher Cowled, Vinod Sundaramoorthy, Diane Green, Cameron Stewart, John Bingham, Carmel M. O’Brien, Megan Dearnley
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Despite being vaccine preventable, rabies (lyssavirus) still has a significant impact on global mortality, disproportionally affecting children under 15 years of age. This neurotropic virus is deft at avoiding the immune system while travelling throu
Externí odkaz:
https://doaj.org/article/b24e887c7bd34c15a221782c04d4c147
Autor:
Wilson K.M. Wong, Mugdha V. Joglekar, Vijit Saini, Guozhi Jiang, Charlotte X. Dong, Alissa Chaitarvornkit, Grzegorz J. Maciag, Dario Gerace, Ryan J. Farr, Sarang N. Satoor, Subhshri Sahu, Tejaswini Sharangdhar, Asma S. Ahmed, Yi Vee Chew, David Liuwantara, Benjamin Heng, Chai K. Lim, Julie Hunter, Andrzej S. Januszewski, Anja E. Sørensen, Ammira S.A. Akil, Jennifer R. Gamble, Thomas Loudovaris, Thomas W. Kay, Helen E. Thomas, Philip J. O'Connell, Gilles J. Guillemin, David Martin, Ann M. Simpson, Wayne J. Hawthorne, Louise T. Dalgaard, Ronald C.W. Ma, Anandwardhan A. Hardikar
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102379- (2021)
Summary: Dicer knockout mouse models demonstrated a key role for microRNAs in pancreatic β-cell function. Studies to identify specific microRNA(s) associated with human (pro-)endocrine gene expression are needed. We profiled microRNAs and key pancre
Externí odkaz:
https://doaj.org/article/016725883f2b42db88e23b368f58c758
Autor:
Leon Tribolet, Emily Kerr, Christopher Cowled, Andrew G. D. Bean, Cameron R. Stewart, Megan Dearnley, Ryan J. Farr
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
In the pursuit of improved diagnostic tests for infectious diseases, several classes of molecules have been scrutinized as prospective biomarkers. Small (18–22 nucleotide), non-coding RNA transcripts called microRNAs (miRNAs) have emerged as promis
Externí odkaz:
https://doaj.org/article/a9f6b02f780946f389f4877dce064e29
Autor:
Vinod Sundaramoorthy, Nathan Godde, Ryan J. Farr, Diane Green, John M. Haynes, John Bingham, Carmel M. O’Brien, Megan Dearnley
Publikováno v:
Viruses, Vol 12, Iss 4, p 359 (2020)
Rabies is a zoonotic neurological infection caused by lyssavirus that continues to result in devastating loss of human life. Many aspects of rabies pathogenesis in human neurons are not well understood. Lack of appropriate ex-vivo models for studying
Externí odkaz:
https://doaj.org/article/9b3aff3cb3c74c0b83b05ddf92256103
Autor:
Anthony C Keech, Yoon Hi Cho, Ryan J. Farr, Emma S. Scott, David N O'Neal, Anandwardhan A. Hardikar, Paul Z. Benitez-Aguirre, Mugdha V. Joglekar, Andrzej S. Januszewski, Luke M. Carroll, Alicia J. Jenkins, Maria E. Craig, Yik Wen Loh, Wilson K. M. Wong, Kim C. Donaghue
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
The aim of this cross-sectional study was to compare plasma C-peptide presence and levels in people without diabetes (CON) and with Type 1 diabetes and relate C-peptide status to clinical factors. In a subset we evaluated 50 microRNAs (miRs) previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd5b712c5082c4c879f559920494d80
https://doaj.org/article/b1ec56fdb12a4c0cb5cb32be78d2f006
https://doaj.org/article/b1ec56fdb12a4c0cb5cb32be78d2f006
Autor:
Christina L. Rootes, Cameron R. Stewart, Ryan J. Farr, John Stenos, Christopher Cowled, Chwan Hong Foo
Host biomarkers are increasingly being considered as tools for improved COVID-19 detection and prognosis. We recently profiled circulating host-encoded microRNA (miRNAs) during SARS-CoV-2 infection, revealing a signature that classified COVID-19 case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a016606203e955b7954b1c8b77615d42
https://doi.org/10.21203/rs.3.rs-907655/v1
https://doi.org/10.21203/rs.3.rs-907655/v1
Autor:
Chwan Hong Foo, Christina L. Rootes, Katherine Kedzierska, Thi H. O. Nguyen, Glenn A. Marsh, Lukasz Kedzierski, Gough G. Au, Allen C. Cheng, Ryan J. Farr, Seshadri S. Vasan, Christopher Cowled, Louise C. Rowntree, Luca Hensen, Cameron R. Stewart
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 7, p e1009759 (2021)
PLoS Pathogens, Vol 17, Iss 7, p e1009759 (2021)
The host response to SARS-CoV-2 infection provide insights into both viral pathogenesis and patient management. The host-encoded microRNA (miRNA) response to SARS-CoV-2 infection, however, remains poorly defined. Here we profiled circulating miRNAs f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abf01b7409d7e76a53bdb685b6db772
http://europepmc.org/articles/PMC8318295
http://europepmc.org/articles/PMC8318295
Autor:
Vinay M. Joglekar, Nageshwar Reddy D, Sarang N. Satoor, Hetherington N, Charlotte X. Dong, Shu Yang, Pandya P, Williams, Rao Gv, Edouard G. Stanley, Ryan J. Farr, Thomas Loudovaris, Sasikala Mitnala, Jhala G, David Tosh, David Martín, Subhshri Sahu, Andrew George Elefanty, Helen E. Thomas, Vee Chew Y, Anandwardhan A. Hardikar, Louise Torp Dalgaard, Wayne J. Hawthorne, Wilson W.K. Wong, Mugdha V. Joglekar, Thiruchevlam D
ObjectivePancreatic islet β-cells are factories for insulin production; however ectopic expression of insulin is also well recognized. The gallbladder is a next-door neighbour to the developing pancreas. Here, we wanted to understand if gallbladders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::719fe460ba1f795e88902398b32adbac
https://doi.org/10.1101/2021.03.02.433636
https://doi.org/10.1101/2021.03.02.433636