Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ryan J. DeBuque"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The lack of scar-free healing and regeneration in many adult human tissues imposes severe limitations on the recovery of function after injury. In stark contrast, salamanders can functionally repair a range of clinically relevant tissues throughout a
Externí odkaz:
https://doaj.org/article/21f5912a93c94a4186fbbced887018de
Autor:
Brooke M. Huuskes, Ryan J. DeBuque, Kevan R. Polkinghorne, Chrishan S. Samuel, Peter G. Kerr, Sharon D. Ricardo
Publikováno v:
Kidney International Reports, Vol 3, Iss 1, Pp 205-211 (2018)
Externí odkaz:
https://doaj.org/article/cc77a957c8484d1fa678edf27bc18ed6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Testing angiogenic potential and function of cells in culture is important for the understanding of the mechanisms that can modulate angiogenesis, especially when discovering novel anti- or pro-angiogenic therapeutics. Commonly used angiogenic assays
Externí odkaz:
https://doaj.org/article/8581351b5a6b4e8398562d304b917360
Publikováno v:
Developmental Dynamics. 251:988-1003
Background Efficient wound healing or pathogen clearance both rely on balanced inflammatory responses. Inflammation is essential for effective innate immune-cell recruitment; however, excessive inflammation will result in local tissue destruction, pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46e667376d213c56a88215c1aa0a3d2c
https://doi.org/10.1002/dvdy.340
https://doi.org/10.1002/dvdy.340
Autor:
Anjana Chandran, Malina J. Ivey, Lina Wang, Alexei Ilinykh, Nadia Rosenthal, Alexander R. Pinto, Komal Arora, Jill T. Kuwabara, Michelle L D'Antoni, Michelle D. Tallquist, Ryan J. Debuque
Publikováno v:
Circulation Research. 118:400-409
Rationale: Accurate knowledge of the cellular composition of the heart is essential to fully understand the changes that occur during pathogenesis and to devise strategies for tissue engineering and regeneration. Objective: To examine the relative fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c3817abe264eed23c66465a39db0c8
https://doi.org/10.1161/circresaha.115.307778
https://doi.org/10.1161/circresaha.115.307778
Publikováno v:
npj Regenerative Medicine, Vol 2, Iss 1, Pp 1-11 (2017)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
In dramatic contrast to the poor repair outcomes for humans and rodent models such as mice, salamanders and some fish species are able to completely regenerate heart tissue following tissue injury, at any life stage. This capacity for complete cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a983a967de2c7a63eec20df5dc35f4
http://hdl.handle.net/10044/1/56525
http://hdl.handle.net/10044/1/56525
Autor:
James W. Godwin, Ryan J. Debuque
Publikováno v:
Innovations in Molecular Mechanisms and Tissue Engineering ISBN: 9783319449944
Urodele amphibians are unrivalled in their ability to regenerate as adults and provide a unique template in which to study the faithful repair of tissues and organs in tetrapods. They display a robust capacity to regenerate a range of clinically rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fae784604bbcd7a074567ad2f527a02
https://doi.org/10.1007/978-3-319-44996-8_1
https://doi.org/10.1007/978-3-319-44996-8_1
Autor:
Ryan J, Debuque, James W, Godwin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1290
The vertebrate immune system comprises both adaptive and innate immune cells with distinct functions during the resolution of inflammation and wound healing after tissue injury. Recent evidence implicates a requirement for innate immune cells from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adc35ecf6f7bbfdf0a6cf4a971b4cc57
https://pubmed.ncbi.nlm.nih.gov/25740489
https://pubmed.ncbi.nlm.nih.gov/25740489
Autor:
Anjana Chandran, Lina Wang, Alexei Ilinykh, James W. Godwin, Lucy Hersey, Alexander R. Pinto, Ryan J. Debuque, Nadia Rosenthal
Publikováno v:
Europe PubMed Central
Aging (Albany NY)
Scopus-Elsevier
Aging (Albany NY)
Scopus-Elsevier
Cardiac tissue macrophages (cTMs) are abundant in the murine heart but the extent to which the cTM phenotype changes with age is unknown. This study characterizes aging-dependent phenotypic changes in cTM subsets. Using theCx3cr1(GFP/+) mouse reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedf7373d666b1112d1658c83e5ecd7f
http://europepmc.org/abstract/med/24861132
http://europepmc.org/abstract/med/24861132