Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ryan J Lu"'
Autor:
Gabriel A Guerrero, Maxime J Derisbourg, Felix AMC Mayr, Laura E Wester, Marco Giorda, J Eike Dinort, Matías D Hartman, Klara Schilling, María José Alonso-De Gennaro, Ryan J Lu, Bérénice A Benayoun, Martin S Denzel
Publikováno v:
eLife, Vol 10 (2021)
Longevity is often associated with stress resistance, but whether they are causally linked is incompletely understood. Here we investigate chemosensory-defective Caenorhabditis elegans mutants that are long-lived and stress resistant. We find that mu
Externí odkaz:
https://doaj.org/article/b5da5aa2ccee4aeda56385feab2e8031
Autor:
Alan Xu, Bryan B. Teefy, Ryan J. Lu, Séverine Nozownik, Alexandra M. Tyers, Dario R. Valenzano, Bérénice A. Benayoun
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-11 (2023)
Abstract The African turquoise killifish is an emerging vertebrate model organism with great potential for aging research due to its naturally short lifespan. Thus far, turquoise killifish aging ‘omic’ studies have examined a single organ, single
Externí odkaz:
https://doaj.org/article/69431960d4694fbe88564530ea988ca5
Publikováno v:
Translational Medicine of Aging, Vol 7, Iss , Pp 1-8 (2023)
Follicle-stimulation hormone (FSH) and FSH receptor (FSHR) signaling is essential for lifelong ovarian and endocrine functions in females. Previous studies have reported that Fshr haploinsufficiency in female mice led to accelerated ovarian aging, in
Externí odkaz:
https://doaj.org/article/df2b92981e1849a88bf26222916418be
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-10 (2022)
Measurement(s) RNA-seq of coding RNA from single cells Technology Type(s) RNA sequencing Factor Type(s) Genotype Sample Characteristic - Organism Mus musculus Sample Characteristic - Environment laboratory facility
Externí odkaz:
https://doaj.org/article/a4d47fe505c44834bc8caacb01904229
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100948- (2021)
Summary: Studies involving neutrophils are steadily increasing, thus creating a need for more optimized and thorough protocols for studying neutrophil function. Here, we present our protocol for extracting mouse bone marrow neutrophils, estimating th
Externí odkaz:
https://doaj.org/article/2a4c036c26764bc6b957bc32de39b994
Autor:
Bo P. Lear, Elizabeth A.N. Thompson, Kendra Rodriguez, Zachary P. Arndt, Saniya Khullar, Payton C. Klosa, Ryan J. Lu, Christopher S. Morrow, Ryan Risgaard, Ella R. Peterson, Brian B. Teefy, Anita Bhattacharyya, Andre M.M. Sousa, Daifeng Wang, Bérénice A. Benayoun, Darcie L. Moore
Publikováno v:
bioRxiv
Injury to adult mammalian central nervous system (CNS) axons results in limited regeneration. Rodent studies have revealed a developmental switch in CNS axon regenerative ability, yet whether this is conserved in humans is unknown. Using human fibrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcf05bc9dbbca524f9ff5ab7704e4fb
https://doi.org/10.1101/2023.05.23.541995
https://doi.org/10.1101/2023.05.23.541995
Autor:
Stewart J. Kim, Patrick Neuhöfer, Caitlin M. Roake, Ryan J. Lu, Robert B. West, Gregory W. Charville, Steven E. Artandi
Publikováno v:
Nature. 597:715-719
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer deaths worldwide1. Studies in human tissues and in mouse models have suggested that for many cancers, stem cells sustain early mutations driving tumour development2,3. For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df369939ace321383983a8f3ea7ff716
https://doi.org/10.1038/s41586-021-03916-2
https://doi.org/10.1038/s41586-021-03916-2
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3bae5e971eeb918798278feb29b72ba
https://doi.org/10.1096/fasebj.2022.36.s1.0i135
https://doi.org/10.1096/fasebj.2022.36.s1.0i135
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 4, Pp 100948-(2021)
STAR Protocols, Vol 2, Iss 4, Pp 100948-(2021)
Summary Studies involving neutrophils are steadily increasing, thus creating a need for more optimized and thorough protocols for studying neutrophil function. Here, we present our protocol for extracting mouse bone marrow neutrophils, estimating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51227c1dafe53513a42fb1ca254ab95d
https://pubmed.ncbi.nlm.nih.gov/34820637
https://pubmed.ncbi.nlm.nih.gov/34820637
Autor:
Nirmal K Sampathkumar, Minhoo Kim, Juan I. Bravo, Bérénice A. Benayoun, Ryan J Lu, Kévin Contrepois, Mathew Ellenberger, Shalina Taylor
Publikováno v:
Nat Aging
Neutrophils are the most abundant human white blood cell and constitute a first line of defense in the innate immune response. Neutrophils are short-lived cells, and thus the impact of organismal aging on neutrophil biology, especially as a function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09366a34cbe09499ec55a2f4eecca93a
https://pubmed.ncbi.nlm.nih.gov/34514433
https://pubmed.ncbi.nlm.nih.gov/34514433