Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ryan Hnatiuk"'
Autor:
Wan Hon Koh, Paul Lopez, Oluwaseun Ajibola, Roshan Parvarchian, Umar Mohammad, Ryan Hnatiuk, Jason Kindrachuk, Thomas T. Murooka
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101427- (2020)
Summary: Trafficking of cell-associated HIV-1 from the genital mucosa to lymphoid organs represents a critical first step toward systemic infection. Mature DCs capture and transmit HIV-1 to T cells, but insights into DC-to-T cell viral spread dynamic
Externí odkaz:
https://doaj.org/article/10b58e347e704367b72fde1bee4c5c60
Autor:
Thomas T. Murooka, Roshan Parvarchian, Umar Mohammad, Wan Hon Koh, Paul Lopez, Ryan Hnatiuk, Jason Kindrachuk, Oluwaseun Ajibola
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101427-(2020)
iScience
iScience
Summary Trafficking of cell-associated HIV-1 from the genital mucosa to lymphoid organs represents a critical first step toward systemic infection. Mature DCs capture and transmit HIV-1 to T cells, but insights into DC-to-T cell viral spread dynamics
Autor:
Oluwaseun Ajibola, Thomas T. Murooka, Jason Kindrachuk, Paul Lopez, Ryan Hnatiuk, Wan Hon Koh, Roshan Parvarchian, Umar Mohammad
Publikováno v:
SSRN Electronic Journal.
The trafficking of cell-associated HIV from the genital mucosa to lymphoid organs represents a critical first step towards systemic infection. Mature DCs capture and transmit HIV to T cells, but insights into DC-to-T cell viral spread dynamics within
Publikováno v:
Journal of virology. 93(18)
Macrophages are susceptible to HIV infection and play an important role in viral dissemination through cell-cell contacts with T cells. However, our current understanding of macrophage-to-T cell HIV transmission is derived from studies that do not co
Autor:
Wan Hon Koh, Paul Lopez, Mauro Di Pilato, Vladimir Vrbanac, Todd M. Allen, Thorsten R. Mempel, Shariq M. Usmani, Ryan Hnatiuk, Thomas T. Murooka, Radwa Sharaf, Maud Deruaz, Andrew D. Luster, Andrew M. Tager, Karen A. Power
Publikováno v:
Cell Host & Microbe. 25:73-86.e5
Summary HIV-1 primarily infects T lymphocytes and uses these motile cells as migratory vehicles for effective dissemination in the host. Paradoxically, the virus at the same time disrupts multiple cellular processes underlying lymphocyte motility, se