Myelin regulatory factor drives remyelination in multiple sclerosis

Autor: Greg J. Duncan, Peggy Assinck, Michael Wegner, G. R. Wayne Moore, Ryan Hirata, Ben Emery, Sohrab B. Manesh, Fraser G. W. Muir, Jason R. Plemel, Jie Liu, Wolfram Tetzlaff, Matan Berson

Publikováno v: Duncan, G J, Plemel, J R, Assinck, P, Manesh, S B, Muir, F G W, Hirata, R, Berson, M, Liu, J, Wegner, M, Emery, B, Moore, G R W & Tetzlaff, W 2017, ' Myelin regulatory factor drives remyelination in multiple sclerosis ', Acta Neuropathologica, vol. 134, no. 3, pp. 403-422 . https://doi.org/10.1007/s00401-017-1741-7

Remyelination is limited in the majority of multiple sclerosis (MS) lesions despite the presence of oligodendrocyte precursor cells (OPCs) in most lesions. This observation has led to the view that a failure of OPCs to fully differentiate underlies r

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https://hdl.handle.net/20.500.11820/9e58597c-2ff0-4ee6-958b-e7f240406b72