Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Ryan H. Livengood"'
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDF - 608K, Supplementary Figure 6. A. Representative BLI of lungs dissected from 4 groups of mice after 2 weeks of treatment as in Fig.7A-B. B. Quantification of BLI of dissected lungs from mice as in (A); 3 independent experiments, n=6/group, Avera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5b84e4ab1fb6a91a961235fe49bb04
https://doi.org/10.1158/1541-7786.22511331.v1
https://doi.org/10.1158/1541-7786.22511331.v1
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
Representative movie of individual MDA-MB-231LN cells treated with Vehicle, MLN8237, eribulin, or MLN8237/eribulin combination, suspended in collagen, and manually tracked over the course of 23 hours toward the serum chemoattractant-containing reserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7997dae0d7d254369c9e07211599f4ae
https://doi.org/10.1158/1535-7163.22508218
https://doi.org/10.1158/1535-7163.22508218
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
The prometastatic protein NEDD9 (neural precursor cell expressed, developmentally downregulated 9) is highly expressed in many cancers and is required for mesenchymal individual cell migration and progression to the invasive stage. Nevertheless, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82643d1cf28555eff2e8c9f79dab9874
https://doi.org/10.1158/1541-7786.c.6539916.v1
https://doi.org/10.1158/1541-7786.c.6539916.v1
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
File contains Supplementary figures: Figure 1: AUKRA analysis in TNBC cell lines in response to drug treatments. Additional TNBC migration/invasion analysis. Figure 2. Representative FACS analysis flow charts of TNBCs undergoing apoptosis. Figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213ece0ad103527f71ce5fc1158f36c3
https://doi.org/10.1158/1535-7163.22508212
https://doi.org/10.1158/1535-7163.22508212
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDF - 131K, Supplementary Figure 5. Rescue of NEDD9-knockdown with CTTN deacetylation mimicking mutant. Immunoprecipitation of CTTN or myc-CTTN with anti-CTTN or anti-myc antibodies from MDA-MB-231 cells co-transfected with siRNA against NEDD9 (N1) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06694b9c0a62360a4e9183a9f905443a
https://doi.org/10.1158/1541-7786.22511334
https://doi.org/10.1158/1541-7786.22511334
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
File contains detailed information on Supplementary video files.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054dc92f0888cd25c16c1d88696ce2b6
https://doi.org/10.1158/1535-7163.22508203.v1
https://doi.org/10.1158/1535-7163.22508203.v1
Autor:
Elena N. Pugacheva, Alexey V. Ivanov, Scott A. Weed, Mark V. Culp, Yuriy V. Loskutov, Varvara K. Kozyreva, Ryan H. Livengood, Polina Y. Kozyulina, Anuradha Rajulapati, Ryan J. Ice, Sarah L. McLaughlin
PDF file - 85K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bac831ee044eb4713d5d20d99aa4999
https://doi.org/10.1158/1541-7786.22509903
https://doi.org/10.1158/1541-7786.22509903
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDf - 35K, Supplementary Figure 4. F-actin pull down assay using lysates from MDA-MB-231 cells expressing shCon, shCTTN and shHDAC6 (HD6) as in Fig.4B (shCon, shHD6). Representative images of WB analysis of F-actin precipitates (P) and supernatant (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a088da88a8a35d1fc90520069231b7a
https://doi.org/10.1158/1541-7786.22511337
https://doi.org/10.1158/1541-7786.22511337
Autor:
Elena N. Pugacheva, Neal Shah, Sricharan Mahavadi, Greg W. Kilby, Pamela S. Cantrell, Callee M. Walsh, Ginger P. Layne, Hannah W. Hazard, Sijin Wen, Mohamad A. Salkeni, Ryan H. Livengood, Kristina Marinak, Matthew B. Smolkin, Fatimah Matalkah, Yuriy V. Loskutov, Brandon C. Jones, Ryan J. Ice, Anna A. Kiseleva, Varvara K. Kozyreva
Table contains diagnostics/characterization of original and patient-derived models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565eebabc18c4342388042be78b893bd
https://doi.org/10.1158/1535-7163.22508206.v1
https://doi.org/10.1158/1535-7163.22508206.v1
Autor:
Elena N. Pugacheva, Alexey V. Ivanov, Scott A. Weed, Mark V. Culp, Yuriy V. Loskutov, Varvara K. Kozyreva, Ryan H. Livengood, Polina Y. Kozyulina, Anuradha Rajulapati, Ryan J. Ice, Sarah L. McLaughlin
PDF file - 2433K, Supplementary Fig. 2 (A). Representative images of live microscopy of BT549-shCon, - shNEDD9 (N4) cells embedded in DQ-Collagen IV 48h post plating. DNA (blue), shRNA expressing cells (RFP, red) and degradation of DQ-Collagen (green
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b7cbd9c0de9614b496848582838c0a
https://doi.org/10.1158/1541-7786.22509912
https://doi.org/10.1158/1541-7786.22509912