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pro vyhledávání: '"Ryan H Kolb"'
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0292423 (2023)
[This corrects the article DOI: 10.1371/journal.pone.0050281.].
Externí odkaz:
https://doaj.org/article/0f42703404b44363a0e7f507285ab25d
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50281 (2012)
Topo II poisons, which target topoisomerase II (topo II) to generate enzyme mediated DNA damage, have been commonly used for anti-cancer treatment. While clinical evidence demonstrate a capability of topo II poisons in inducing apoptosis in cancer ce
Externí odkaz:
https://doaj.org/article/e4bd4032b40b482e95b87d2aad5ed2f5
Autor:
Zhixin Wang, Ashley L. Hein, Surinder K. Batra, Ying Yan, Kenneth H. Cowan, Patrick M. Greer, Ryan H. Kolb
Publikováno v:
Oncogene. 34:2215-2226
In response to γ-irradiation (IR)-induced DNA damage, activation of cell cycle checkpoints results in cell cycle arrest, allowing time for DNA repair before cell cycle re-entry. Human cells contain G1 and G2 cell cycle checkpoints. While G1 checkpoi
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50281 (2012)
PLoS ONE
PLoS ONE
Topo II poisons, which target topoisomerase II (topo II) to generate enzyme mediated DNA damage, have been commonly used for anti-cancer treatment. While clinical evidence demonstrate a capability of topo II poisons in inducing apoptosis in cancer ce
Publikováno v:
Breast Cancer Research : BCR
Introduction In response to gamma-irradiation (IR)-induced double-strand DNA breaks, cells undergo cell-cycle arrest, allowing time for DNA repair before reentering the cell cycle. G2/M checkpoint activation involves activation of ataxia telangiectas