Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ryan G. Soderquist"'
Publikováno v:
Biotechnology Progress. 31:983-989
An orthogonal chromatography methodology for the enrichment of host cell protein (HCP) species relative to monoclonal antibody (mAb) products was developed and applied for the successful enrichment of HCP from post-Protein A process pools for seven d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92c675677ffc9ceacbe51644b2e1970
https://doi.org/10.1002/btpr.2114
https://doi.org/10.1002/btpr.2114
Autor:
Ryan G. Soderquist, Melissa J. Mahoney
Publikováno v:
Expert Opinion on Drug Delivery. 7:285-293
Therapeutic proteins and DNA constructs offer promise for the treatment of central nervous system disorders, yet significant biological barriers limit the ability of these molecules to reach the central nervous system from the bloodstream. Direct adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c116e8a1da2d2edb8ab1ac8f83157306
https://doi.org/10.1517/17425240903540205
https://doi.org/10.1517/17425240903540205
Publikováno v:
Neuromodulation : journal of the International Neuromodulation Society. 15(6)
Introduction: Current research indicates that chronic peripheral neuropathic pain includes a role for glia and the actions of proinflammatory factors. This review briefly discusses the glial and cytokine responses that occur following peripheral nerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0f71d9ca0e1d1f31c368ef276dc142
https://pubmed.ncbi.nlm.nih.gov/22672183
https://pubmed.ncbi.nlm.nih.gov/22672183
Autor:
Evan M. Sloane, Erin D. Milligan, Luke D. Amer, Linda R. Watkins, Scott M. Johnson, Stephen Poole, Makenzie T. Lewis, Jacqueline A. Harrison, Ellen C. Dengler, Courtney S. Young, Melissa J. Mahoney, Lisa C. Loram, Ryan G. Soderquist, Matthew G. Frank
Publikováno v:
Pharmaceutical research. 27(5)
Interleukin-10 (IL-10) is an anti-inflammatory molecule that has achieved interest as a therapeutic for neuropathic pain. In this work, the potential of plasmid DNA-encoding IL-10 (pDNA-IL-10) slowly released from biodegradable microparticles to prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4453bba4248739cceee76f2e770e1633
https://pubmed.ncbi.nlm.nih.gov/20224990
https://pubmed.ncbi.nlm.nih.gov/20224990
Autor:
Kirk W. Johnson, Ryan G. Soderquist, Melissa J. Mahoney, Linda R. Watkins, Raymond A. Chavez, Erin D. Milligan, Jacqueline A. Harrison
Publikováno v:
Journal of biomedical materials research. Part A. 93(3)
The anti-inflammatory cytokine interleukin-10 (IL-10) shows promise for the treatment of neuropathic pain, but for IL-10 to be clinically useful as a short-term therapeutic its duration needs to be improved. In this study, IL-10 was covalently modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51a3d95fa365e765be37bdd134d3f52
https://pubmed.ncbi.nlm.nih.gov/19768789
https://pubmed.ncbi.nlm.nih.gov/19768789
Autor:
Linda R. Watkins, Melissa J. Mahoney, Erin D. Milligan, Evan M. Sloane, Ryan G. Soderquist, Steven F. Maier
Traditional approaches to treating chronic neuropathic pain largely focus on manipulations directly altering neuronal activity or neuron-to-neuron communication. Recently, however, it has become clear that glial cells (including microglia and astrogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f023e941cbb0fb9d32a78b5012aaa243
https://europepmc.org/articles/PMC2756299/
https://europepmc.org/articles/PMC2756299/
Publikováno v:
Synaptic Plasticity in Pain ISBN: 9781441902252
Chronic pain is a significant national health problem which afflicts more than 25% of adults in the United States, alone, and is the most common reason individuals seek medical care. Chronic and recurrent pain, which persists or recurs for more than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e4b1fa2cba468fa4067e984ba45eea
https://doi.org/10.1007/978-1-4419-0226-9_17
https://doi.org/10.1007/978-1-4419-0226-9_17
Autor:
Kirk W. Johnson, Jacqueline A. Harrison, Klarika K. Douvas, Joseph M. Potter, Linda R. Watkins, Melissa J. Mahoney, Evan M. Sloane, Ryan G. Soderquist, Travis S. Hughes, Erin D. Milligan, Raymond A. Chavez
Publikováno v:
Journal of biomedical materials research. Part A. 91(3)
Brain-derived neurotrophic factor (BDNF) was covalently attached to polyethylene glycol (PEG) in order to enhance delivery to the spinal cord via the cerebrospinal fluid (intrathecal administration). By varying reaction conditions, mixtures of BDNF c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa3892c37f836c42c4f2ce1727e0fb1
https://pubmed.ncbi.nlm.nih.gov/19048635
https://pubmed.ncbi.nlm.nih.gov/19048635
Autor:
Ryan G. Soderquist, James M. Lee
Publikováno v:
Applications of Cell Immobilisation Biotechnology ISBN: 9781402032295
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b0c3d77867f6d20c9f06ee8df1cb7de
https://doi.org/10.1007/1-4020-3363-x_27
https://doi.org/10.1007/1-4020-3363-x_27
Autor:
Ryan G. Soderquist, James M. Lee
Publikováno v:
Plant cell reports. 24(2)
Human granulocyte-macrophage colony-stimulating factor (GM-CSF) was produced from transgenic Nicotiana tabacum cells. The application of osmotic stress through the addition of 90 g/l mannitol to the plant cell medium enhanced the maximum extracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12e1b5a1f05701abdb2b6fc162cf5a2
https://pubmed.ncbi.nlm.nih.gov/15700142
https://pubmed.ncbi.nlm.nih.gov/15700142