Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ryan G. Holzer"'
Supplementary Figure 2 from Breast Cancer Cells Stimulate Neutrophils to Produce Oncostatin M: Potential Implications for Tumor Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc97c3427c54c4df11fe4ccaf8d2273
https://doi.org/10.1158/0008-5472.22365501
https://doi.org/10.1158/0008-5472.22365501
Tumor-associated and tumor-infiltrating neutrophils (TAN) and macrophages (TAM) can account for as much as 50% of the total tumor mass in invasive breast carcinomas. It is thought that tumors secrete factors that elicit a wound-repair response from T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efecf08b5e4e57ed2b0c3f81732ddde
https://doi.org/10.1158/0008-5472.c.6494733.v1
https://doi.org/10.1158/0008-5472.c.6494733.v1
Supplementary Figure 1 from Breast Cancer Cells Stimulate Neutrophils to Produce Oncostatin M: Potential Implications for Tumor Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79697fc2a3f2e263b984210e8200eac9
https://doi.org/10.1158/0008-5472.22365504.v1
https://doi.org/10.1158/0008-5472.22365504.v1
Autor:
Ryan G. Holzer, Alex Ide, Danielle Hedeen, Ken Tawara, Ryan Fox, Jacqueline Emathinger, Andrew Oler, Madhuri Nandakumar, Cheryl L. Jorcyk, Daniel Greiner, Dollie LaJoie, Hannah Scott
Publikováno v:
Translational Oncology, Vol 12, Iss 2, Pp 245-255 (2019)
Breast cancer cell-response to inflammatory cytokines such as interleukin-6 (IL-6) and oncostatin M (OSM) may affect the course of clinical disease in a cancer subtype-dependent manner. Furthermore, vascular endothelial growth factor A (VEGF) secreti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea02ba6bda8b1049cd3267bc85f06dd
http://www.sciencedirect.com/science/article/pii/S1936523318303802
http://www.sciencedirect.com/science/article/pii/S1936523318303802
Autor:
Çiǧdem Atay, David Tarin, Thomas J. Deerinck, Xuefeng Wu, Scott R. VandenBerg, Mert Erkan, David W. Dawson, Jorge Moscat, Jun Hee Lee, Jörg Kleeff, Melek C. Arkan, Ning Li, Maria T. Diaz-Meco, Anna S. Gukovskaya, Jelena Todoric, Michael Karin, Ilya Gukovsky, Ryan G. Holzer, Donald P. Pizzo, Eek Joong Park, Hisanobu Ogata
Publikováno v:
Journal of Clinical Investigation. 123:2231-2243
Chronic pancreatitis is an inflammatory disease that causes progressive destruction of pancreatic acinar cells and, ultimately, loss of pancreatic function. We investigated the role of IκB kinase α (IKKα) in pancreatic homeostasis. Pancreas-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8481c595ed5c28452979addcbd3df3
https://doi.org/10.1172/jci64498
https://doi.org/10.1172/jci64498
Autor:
Christoph H. Österreicher, Hiroyuki Takahashi, Michael Karin, Ryan G. Holzer, Jun Hee Lee, Syed Raza Ali, Guobin He, Eek Joong Park, Guann-Yi Yu
Publikováno v:
Cell. 140:197-208
SummaryEpidemiological studies indicate that overweight and obesity are associated with increased cancer risk. To study how obesity augments cancer risk and development, we focused on hepatocellular carcinoma (HCC), the common form of liver cancer wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc5aeafeaa06fd783a16447b47faf40
https://doi.org/10.1016/j.cell.2009.12.052
https://doi.org/10.1016/j.cell.2009.12.052
Autor:
Cheryl L. Jorcyk, Christina A. MacDougall, Colin R. Soares, Micaela Vargas, Ryan G. Holzer, Alexander E. Ide
Publikováno v:
The Prostate. 64:139-148
BACKGROUND Hepatocyte growth factor/scatter factor (HGF/SF) facilitates intercellular communication between the epithelial carcinoma and its surrounding stromal tissue during metastatic invasion through interaction with its proto-oncogenic receptor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85703a957207a8db946b5686e66526c
https://doi.org/10.1002/pros.20226
https://doi.org/10.1002/pros.20226
Publikováno v:
Clinical & Experimental Metastasis. 21:167-176
Previously, oncostatin M (OSM) has been shown to inhibit the proliferation of breast cancer cells in vitro. Circumstantial evidence, however, suggests that OSM could be involved in the development of a metastatic phenotype in vivo. We examined the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf70ba0936e6d2db72e70963dc980f90
https://doi.org/10.1023/b:clin.0000024760.02667.db
https://doi.org/10.1023/b:clin.0000024760.02667.db
Autor:
Ryan G. Holzer, Christina MacDougall, Jeffrey E. Green, Kristi Atwood, Cheryl L. Jorcyk, Gerry Cortright
Publikováno v:
Breast Cancer Research and Treatment. 77:65-76
We have developed four new mammary adenocarcinoma cell lines from the C3(1)/SV40 Large T-antigen (Tag) transgenic mouse model: M28N2 and M27H4 (weakly tumorigenic), M6 (carcinoma), and M6C (metastatic). The C3(1) promoter directs Tag expression to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5ffa5813ad38c382e02a346ac238df
https://doi.org/10.1023/a:1021175931177
https://doi.org/10.1023/a:1021175931177
Autor:
Helen Tran, EekJoong Park, Crystal Choi, Ning Li, Ryan G. Holzer, Monica Chen, Giovanni Solinas, Michael Karin
SummarySaturated fatty acids (FA) exert adverse health effects and are more likely to cause insulin resistance and type 2 diabetes than unsaturated FA, some of which exert protective and beneficial effects. Saturated FA, but not unsaturated FA, activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838f629b0e21539ba2e43579c50c4d6c
http://doc.rero.ch/record/28196/files/sol_sfa_sm.pdf
http://doc.rero.ch/record/28196/files/sol_sfa_sm.pdf