Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ryan G. Epton"'
Autor:
Nantachai Inprung, Hon Eong Ho, James A. Rossi-Ashton, Ryan G. Epton, Adrian C. Whitwood, Jason M. Lynam, Richard J. K. Taylor, Michael J. James, William P. Unsworth
Publikováno v:
Organic Letters. 24:668-674
Indole-ynones have been established as general substrates for radical dearomatizing spirocyclization cascade reactions. Five distinct and varied synthetic protocols have been developed─cyanomethylation, sulfonylation, trifluoromethylation, stannyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3217e7dca5f5085e4e5f9eddc1fd622e
https://doi.org/10.1021/acs.orglett.1c04098
https://doi.org/10.1021/acs.orglett.1c04098
Autor:
Zhongzhen Yang, Illya Zalessky, Ryan G. Epton, Adrian C. Whitwood, Jason M. Lynam, William P. Unsworth
Publikováno v:
Angewandte Chemie International Edition. 62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655dc801ccd6f6034c954eeb878f4711
https://doi.org/10.1002/anie.202217178
https://doi.org/10.1002/anie.202217178
Autor:
Meghan J. Oddy, Daniel A. Kusza, Ryan G. Epton, Jason M. Lynam, William P. Unsworth, Wade F. Petersen
Publikováno v:
Angewandte Chemie. 134
The synthesis of 2-azetidinones (β-lactams) from simple acrylamide starting materials by visible-light-mediated energy transfer catalysis is reported. The reaction features a C(sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845bc9233014a0c0ecc147e9ccd7a8f0
https://doi.org/10.1002/ange.202213086
https://doi.org/10.1002/ange.202213086
Publikováno v:
Israel Journal of Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::785a9bc63577cf97e8fe09a168d3d07c
https://doi.org/10.1002/ijch.202200033
https://doi.org/10.1002/ijch.202200033
Publikováno v:
Organic & Biomolecular Chemistry. 19:1404-1411
A side chain insertion method for the ring expansion of lactams into macrocyclic thiolactones is reported, that can also be incorporated into Successive Ring Expansion (SuRE) sequences. The reactions are less thermodynamically favourable than the ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de94a2e27decfafa2bb6ac9769c6f03e
https://doi.org/10.1039/d0ob02502j
https://doi.org/10.1039/d0ob02502j
Autor:
Emilie Marotte, Kleopas Y. Palate, Ryan G. Epton, William P. Unsworth, Katie J. Lamb, Aggie Lawer, Thomas C. Stephens, Jade K. Sangha, Jason M. Lynam, Mahendar Lodi
Publikováno v:
CHEMISTRY-A EUROPEAN JOURNAL
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry (Weinheim an Der Bergstrasse, Germany)
The outcome of ring‐expansion reactions based on amino/hydroxyacid side‐chain insertion is strongly dependent on ring size. This manuscript, which builds upon our previous work on Successive Ring Expansion (SuRE) methods, details efforts to bette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6598983bdb9d85a6195630453a973576
https://doi.org/10.1002/chem.202002164
https://doi.org/10.1002/chem.202002164
Publikováno v:
European Journal of Organic Chemistry. 2019:5563-5571
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84bd43e322877d05997215256d026fa2
https://doi.org/10.1002/ejoc.201900798
https://doi.org/10.1002/ejoc.201900798
Autor:
Peter O'Brien, Hon Eong Ho, Michael J. James, Ryan G. Epton, James R. Donald, James A. Rossi-Ashton, Angela Pagano, William P. Unsworth, Jonathan C. Churchill, Richard J. K. Taylor
Publikováno v:
Chemical Science
Ho, H E, Pagano, A, Rossi-ashton, J A, Donald, J R, Epton, R G, Churchill, J C, James, M J, O'brien, P, Taylor, R J K & Unsworth, W P 2019, ' Visible-light-induced intramolecular charge transfer in the radical spirocyclisation of indole-tethered ynones ', Chemical Science, vol. 11, no. 5, pp. 1353-1360 . https://doi.org/10.1039/C9SC05311E
Ho, H E, Pagano, A, Rossi-ashton, J A, Donald, J R, Epton, R G, Churchill, J C, James, M J, O'brien, P, Taylor, R J K & Unsworth, W P 2019, ' Visible-light-induced intramolecular charge transfer in the radical spirocyclisation of indole-tethered ynones ', Chemical Science, vol. 11, no. 5, pp. 1353-1360 . https://doi.org/10.1039/C9SC05311E
Indole-tethered ynones form an intramolecular electron donor–acceptor complex that can undergo visible-light-induced charge transfer to promote thiyl radical generation from thiols. This initiates a novel radical chain sequence, based on dearomatis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054e1d1028c891c2723beb56e6170668
https://eprints.whiterose.ac.uk/157506/1/c9sc05311e.pdf
https://eprints.whiterose.ac.uk/157506/1/c9sc05311e.pdf
Autor:
Ryan G. Epton, Jason M. Lynam, Bradley J Challis, William P. Unsworth, Thomas C. Stephens, James A. Rossi-Ashton, Aggie Lawer
Publikováno v:
Angewandte Chemie (International ed. in English). 58(39)
A strategy for the synthesis of medium-sized lactones and lactams from linear precursors is described in which an amine acts as an internal nucleophilic catalyst to facilitate a novel cyclisation/ring expansion cascade sequence. This method obviates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab93ce776638802343e08279457ccc01
https://pubmed.ncbi.nlm.nih.gov/31340086
https://pubmed.ncbi.nlm.nih.gov/31340086