Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ryan Farid"'
Autor:
Amal A. H. Gadalla, Giulia Siciliano, Ryan Farid, Pietro Alano, Lisa Ranford-Cartwright, James S. McCarthy, Joanne Thompson, Hamza A Babiker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The use of quantitative qRT-PCR assays for detection and quantification of late gametocyte stages has revealed the high transmission capacity of the human malaria parasite, Plasmodium falciparum. To understand how the parasite adjusts its tr
Externí odkaz:
https://doaj.org/article/e868c3a6213e4d65811a67f617760857
Autor:
Matthias Ernst, Toby J. Phesse, Paul M. Waring, Dennis Huszar, Joachim Elzer, Ryan Farid, Stefan Thiem, Tracy Putoczki, Michael Buchert, Emma Stuart
Aberrant activation of the latent transcription factor STAT3 and its downstream targets is a common feature of epithelial-derived human cancers, including those of the gastrointestinal tract. Mouse models of gastrointestinal malignancy implicate Stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6909aa57204ed9c2ae2994aa98111eb
https://doi.org/10.1158/1535-7163.c.6536220
https://doi.org/10.1158/1535-7163.c.6536220
Autor:
Matthias Ernst, Toby J. Phesse, Paul M. Waring, Dennis Huszar, Joachim Elzer, Ryan Farid, Stefan Thiem, Tracy Putoczki, Michael Buchert, Emma Stuart
PDF file - 141K, Table S1. Primers used for quantitative PCR analysis. Table S2. Antibodies (all diluted 1:1000) used for immunohistochemistry and Western Blot analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d12f167ae93b1870534adbf94ce267
https://doi.org/10.1158/1535-7163.22499691.v1
https://doi.org/10.1158/1535-7163.22499691.v1
Autor:
Matthias Ernst, Toby J. Phesse, Paul M. Waring, Dennis Huszar, Joachim Elzer, Ryan Farid, Stefan Thiem, Tracy Putoczki, Michael Buchert, Emma Stuart
PDF file - 1978K, Supplementary Figure 1: The gpA33 locus confers expression of tamoxifen-activatable CreERT2 transgene to the metaplastic epithelium of gastric tumors of gp130F/F mice. Supplementary Figure 2: AZD1480-treatment reduces gastric tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307e6924354e7af1c4dec54090432fdb
https://doi.org/10.1158/1535-7163.22499688.v1
https://doi.org/10.1158/1535-7163.22499688.v1
Autor:
Hamza A. Babiker, Lisa C. Ranford-Cartwright, Giulia Siciliano, James S. McCarthy, Amal A. H. Gadalla, Ryan Farid, Pietro Alano, Joanne Thompson
Publikováno v:
Gadalla, A A H, Siciliano, G, Farid, R, Alano, P, Ranford-Cartwright, L, McCarthy, J S, Thompson, J & Babiker, H A 2021, ' Real-time PCR assays for detection and quantification of early P. falciparum gametocyte stages ', Scientific Reports, vol. 11, 19118 . https://doi.org/10.1038/s41598-021-97456-4
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The use of quantitative qRT-PCR assays for detection and quantification of late gametocyte stages has revealed the high transmission capacity of the human malaria parasite, Plasmodium falciparum. To understand how the parasite adjusts its transmissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc3c800d71938c9cbbb5304e71786e8
https://hdl.handle.net/20.500.11820/0cc14cee-2504-48e9-b640-fba9530c8a6e
https://hdl.handle.net/20.500.11820/0cc14cee-2504-48e9-b640-fba9530c8a6e
Publikováno v:
The Journal of Infectious Diseases
The recent focus on the elimination of malaria has led to an increased interest in the role of sexual stages in its transmission. We introduce Plasmodium falciparum gametocyte exported protein-5 (PfGEXP5) transcript analysis as an important tool for
Autor:
Toby J. Phesse, Tracy L Putoczki, Paul Waring, Joachim Elzer, Dennis Huszar, Matthias Ernst, Emma Charlotte Stuart, Ryan Farid, Stefan Thiem, Michael Buchert
Publikováno v:
Molecular Cancer Therapeutics. 13:468-474
Aberrant activation of the latent transcription factor STAT3 and its downstream targets is a common feature of epithelial-derived human cancers, including those of the gastrointestinal tract. Mouse models of gastrointestinal malignancy implicate Stat
Autor:
Yeliz Boglev, Adele Preaudet, Matthias Ernst, Rita A. Busuttil, Tracy L Putoczki, Andrea Loving, Brent S. McKenzie, David Horst, Irina Pleines, Oliver M. Sieber, Paul Ziegler, Andrew G. Jarnicki, Nicholas J. Wilson, Stefan Thiem, Ryan Farid, Paul M Nguyen, Kirsten Edwards, Rodney B. Luwor, Benjamin T. Kile, Florian R. Greten, Andrew D. Nash, Joan K. Heath, Alex Boussioutas
Publikováno v:
Cancer Cell
SummaryAmong the cytokines linked to inflammation-associated cancer, interleukin (IL)-6 drives many of the cancer “hallmarks” through downstream activation of the gp130/STAT3 signaling pathway. However, we show that the related cytokine IL-11 has
Publikováno v:
Pathology. 48:S77
Autor:
Christopher G. Love, Zhengdeng Lei, Steve Rozen, Andrew G. Jarnicki, Michelle Palmieri, Adele Preaudet, Fred Schaper, Michael Hallek, Patrick Tan, Alex Boussioutas, Matthias Ernst, Tracy L Putoczki, Ryan Farid, Thomas P. Pierce, Stefan Thiem, Veena Gopalakrishnan, Bruno Catimel, Michael Buchert
Publikováno v:
The Journal of clinical investigation. 123(2)
Gastrointestinal cancers are frequently associated with chronic inflammation and excessive secretion of IL-6 family cytokines, which promote tumorigenesis through persistent activation of the GP130/JAK/STAT3 pathway. Although tumor progression can be