Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ryan D. Shepard"'
Autor:
Sarah C. Simmons, William J. Flerlage, Ludovic D. Langlois, Ryan D. Shepard, Christopher Bouslog, Emily H. Thomas, Kaitlyn M. Gouty, Jennifer L. Sanderson, Shawn Gouty, Brian M. Cox, Mark L. Dell’Acqua, Fereshteh S. Nugent
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract The scaffolding A-kinase anchoring protein 150 (AKAP150) is critically involved in kinase and phosphatase regulation of synaptic transmission/plasticity, and neuronal excitability. Emerging evidence also suggests that AKAP150 signaling may p
Externí odkaz:
https://doaj.org/article/d0756070792248e3952cc58c533d07ad
Autor:
Ryan D. Shepard, Fereshteh S. Nugent
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Adverse events and childhood trauma increase the susceptibility towards developing psychiatric disorders (substance use disorder, anxiety, depression, etc.) in adulthood. Although there are treatment strategies that have utility in combating these ps
Externí odkaz:
https://doaj.org/article/659ec54d0f8345bcb80982a4536e13d9
Autor:
Sarah C. Simmons, Ryan D. Shepard, Shawn Gouty, Ludovic D. Langlois, William J. Flerlage, Brian M. Cox, Fereshteh S. Nugent
Publikováno v:
Neurobiology of Stress, Vol 13, Iss , Pp 100267- (2020)
The lateral habenula (LHb) is an epithalamic brain region associated with value-based decision making and stress evasion through its modulation of dopamine (DA)-mediated reward circuitry. Specifically, increased activity of the LHb is associated with
Externí odkaz:
https://doaj.org/article/88499a55428542f7ac83e5501b9e346f
Autor:
Ryan D. Shepard, Fereshteh S. Nugent
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Psychiatric illnesses are a major public health concern due to their prevalence and heterogeneity of symptom presentation resulting from a lack of efficacious treatments. Although dysregulated dopamine (DA) signaling has been observed in a myriad of
Externí odkaz:
https://doaj.org/article/29f6a9695ccc412e971bb85522a0a16f
Autor:
Ryan D. Shepard, Ludovic D. Langlois, Caroline A. Browne, Aylar Berenji, Irwin Lucki, Fereshteh S. Nugent
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Mounting evidence suggests that the long-term effects of adverse early life stressors on vulnerability to drug addiction and mood disorders are related to dysfunction of brain monoaminergic signaling in reward circuits. Recently, there has been a gro
Externí odkaz:
https://doaj.org/article/340e7cbabfb24a77b4247cee4a3e6c84
Autor:
Nobuyoshi Akimitsu, Marina Alexeeva, Juliana Almeida, Rodolfo Daniel Ávila-Avilés, Jérémy Berthelier, Akanksha Bhatnagar, Maria Boskovic, Nancy V.N. Carullo, J. Armando Casas-Mollano, Frances A. Champagne, Taiping Chen, Ravindresh Chhabra, James P. Curley, Gareth W. Davison, Gary L. Dunbar, Thomas Eggermann, Felice Elefant, Peter D. Fransquet, Hodaka Fujii, Toshitsugu Fujita, Leonardo Furci, Jose Garcia, Balaram Ghosh, Linn Gillberg, Karen Giménez-Orenga, Courtney W. Hanna, Zdenko Herceg, J. Manuel Hernández-Hernández, Line Hjort, Xiaotong Hu, Eveline M. Ibeagha-Awemu, Ali Jawaid, Wei Jiang, Oscar Juez, Ashley M. Karnay, Kentaro Kawata, Hasan Khatib, Eric W. Klee, Kerstin Klein, Eloïse A. Kremer, Ilkka Kronholm, Ho-Sun Lee, Frédérique Magdinier, Isabelle M. Mansuy, Rahia Mashoodh, Mihaly Mezei, Maria Miah, Matin Miryeganeh, Shiraz Mujtaba, Pamela N. Munster, Rabih Murr, Rūta Navakauskienė, Claudia Negrón-Lomas, Fereshteh S. Nugent, Elisa Oltra, Rena Onoguchi-Mizutani, Nail Can Öztürk, Romain Pacaud, Jacob Peedicayil, Prasad Pethe, Gerd P. Pfeifer, Sravani Pulya, Tibor A. Rauch, Marisol Resendiz, Marcus Roalsø, Jérôme D. Robin, Julien Rossignol, Joanne Ryan, Cíntia Barros Santos-Rebouças, Hidetoshi Saze, Ryan D. Shepard, Philippe Silar, Athena Sklias, Susan L. Slager, Kjetil Søreide, Bhairavi Srinageshwar, David M. Suter, Kenzui Taniue, Scott Thomas, Shulan Tian, Trygve O. Tollefsbol, Mark van der Giezen, Ludovica Vanzan, Günter Vogt, Darryl S. Watkins, Martin M. Watson, Loo Keat Wei, Jo Wrigglesworth, Toshimichi Yamada, Huihuang Yan, Jie Yang, Zhengzhou Ying, Ericka Zacarias, Feng C. Zhou
Publikováno v:
Handbook of Epigenetics ISBN: 9780323919098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d4acac4d28fc4a91274d2bedcade435
https://doi.org/10.1016/b978-0-323-91909-8.00047-5
https://doi.org/10.1016/b978-0-323-91909-8.00047-5
Autor:
Ryan D. Shepard, Fereshteh S. Nugent
Publikováno v:
Handbook of Epigenetics ISBN: 9780323919098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d131700d04d05fd2212a623769f90ac3
https://doi.org/10.1016/b978-0-323-91909-8.00040-2
https://doi.org/10.1016/b978-0-323-91909-8.00040-2
Publikováno v:
Trends Neurosci
The vast majority of fast inhibitory transmission in the brain is mediated by GABA acting on GABA(A) receptors (GABA(A)Rs), which provides inhibitory balance to excitatory drive and controls neuronal output. GABA(A)Rs are also effectively targeted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb78c1abe698c4da45e30d98c7ea046b
https://doi.org/10.1016/j.tins.2020.10.011
https://doi.org/10.1016/j.tins.2020.10.011
Sleep is a fundamental physiological process conserved across most species. As such, deficits in sleep can result in a myriad of psychological and physical health issues. However, the mechanisms underlying the induction of sleep are relatively unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee7ebc42181f2186b1e8f7572295bf3c
https://doi.org/10.1101/2021.11.08.467738
https://doi.org/10.1101/2021.11.08.467738
GABA-A receptors (GABAARs) are crucial for development and regulation of the central nervous system. Altered GABAergic signaling is hypothesized to be involved in the pathophysiology of neurodevelopmental disorders. Nevertheless, how aberrant cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9062bb70eb26ec6f670d265ef12eee0b
https://doi.org/10.1101/2021.08.02.454792
https://doi.org/10.1101/2021.08.02.454792