Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ryan D. R. Brown"'
Autor:
Briana N. James, Cynthia Weigel, Christopher D. Green, Ryan D. R. Brown, Elisa N. D. Palladino, Anuj Tharakan, Sheldon Milstien, Richard L. Proia, Rebecca K. Martin, Sarah Spiegel
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e5c78b7a806358bd9615ac76ee9ff2f
https://doi.org/10.1096/fj.202201821r
https://doi.org/10.1096/fj.202201821r
Autor:
Federico Torta, Jeongah Oh, Mariam Alsanafi, Susan Pyne, David R. Adams, Ryan D. R. Brown, Nigel J. Pyne
Publikováno v:
Cell Biochemistry and Biophysics
Dihydroceramide desaturase (Degs1) catalyses the introduction of a 4,5-trans double bond into dihydroceramide to form ceramide. We show here that Degs1 is polyubiquitinated in response to retinol derivatives, phenolic compounds or anti-oxidants in HE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4652a3ab193d4d94d81478e2ec478e3b
https://doi.org/10.1007/s12013-021-00990-1
https://doi.org/10.1007/s12013-021-00990-1
Autor:
Christopher D. Green, Cynthia Weigel, Ryan D. R. Brown, Pierre Bedossa, Mikhail Dozmorov, Arun J. Sanyal, Sarah Spiegel
Publikováno v:
The FASEB Journal. 36
Non-alcoholic steatohepatitis (NASH) results from the accumulation of excessive liver lipids leading to hepatocellular injury, inflammation, and fibrosis that greatly increase the risk for hepatocellular carcinoma (HCC). Despite the well-characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3442ab2c5a71269449b8b883a01259c
https://doi.org/10.1096/fj.202200346r
https://doi.org/10.1096/fj.202200346r
Autor:
Nigel J. Pyne, Rothwelle J. Tate, Federico Torta, David R. Adams, Jeongah Oh, Susan Pyne, Ryan D. R. Brown, Margaret R. Cunningham, Ben E.P. Veerman
Publikováno v:
The Journal of Biological Chemistry
The translocation of sphingosine kinase 1 (SK1) to the plasma membrane (PM) is crucial in promoting oncogenesis. We have previously proposed that SK1 exists as both a monomer and dimer in equilibrium, although it is unclear whether these species tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3396474707d566c93b76fdd17ca71c
http://europepmc.org/articles/PMC8135045
http://europepmc.org/articles/PMC8135045
Autor:
Ryan D. R. Brown, Marija Sajic, Lucy M. Hinder, Fabian Peters, Amy E. Rumora, Sharlini Varatharajah, Anish A. Kanhai, Kenneth Smith, Masha G. Savelieff, Eva L. Feldman, Giacomo Dentoni, Caroline Casey
Publikováno v:
J Neurosci
Peripheral neuropathy (PN) is the most common complication of prediabetes and diabetes. PN causes severe morbidity for Type 2 diabetes (T2D) and prediabetes patients, including limb pain followed by numbness resulting from peripheral nerve damage. PN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cd5dc07f6aecb28796a55668b6f65e
https://pubmed.ncbi.nlm.nih.gov/33785643
https://pubmed.ncbi.nlm.nih.gov/33785643