Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ryan D. Mohan"'
Autor:
Rituparna Goswami, Abudu I. Bello, Joe Bean, Kara M. Costanzo, Bwaar Omer, Dayanne Cornelio-Parra, Revan Odah, Amit Ahluwalia, Shefaa K. Allan, Nghi Nguyen, Taylor Shores, N. Ahmad Aziz, Ryan D. Mohan
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Spinocerebellar ataxia (SCA) type 7 (SCA7) is caused by a CAG trinucleotide repeat expansion in the ataxin 7 (ATXN7) gene, which results in polyglutamine expansion at the amino terminus of the ATXN7 protein. Although ATXN7 is expressed widely, the be
Externí odkaz:
https://doaj.org/article/fb88ef600da64410a44a5fcb647d552a
Autor:
Joe Bean, Ryan D. Mohan
Publikováno v:
EBioMedicine, Vol 63, Iss , Pp 103179- (2021)
Externí odkaz:
https://doaj.org/article/d13f97c62ea3497f9d048b672146f7df
Autor:
Abudu I. Bello, Rituparna Goswami, Shelby L. Brown, Kara Costanzo, Taylor Shores, Shefaa Allan, Revan Odah, Ryan D. Mohan
Publikováno v:
Cells, Vol 11, Iss 3, p 556 (2022)
Ubiquitination refers to the conjugation of the ubiquitin protein (a small protein highly conserved among eukaryotes) to itself or to other proteins through differential use of ubiquitin’s seven internal linkage sites or the amino-terminal amino gr
Externí odkaz:
https://doaj.org/article/12603165ab0749c29d75fb49a6e88229
Autor:
Vy T Ngo, Minh Q Nguyen, Ada Thapa, Shea M Sullivan, Ryan D Mohan, Essence Blankinship, Dominic Buckley, Austin O Dada, Veronica Cloud
Publikováno v:
Biotechniques
Drosophila melanogaster possesses a complex nervous system, regulating sophisticated behavioral outputs, that serves as a powerful model for dissecting molecular mechanisms underlying neuronal function and neurodegenerative disease. Immunofluorescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d3c9919ea1d670dc838c31a06d58fa
https://doi.org/10.2144/btn-2018-0067
https://doi.org/10.2144/btn-2018-0067
Autor:
Na'ama Flint Brodsly, Oksana Maksimenko, Eliya Bitman-Lotan, Todd E. Druley, Salwa Danial, Ryan D Mohan, Lena Israitel, Gal Raz, Amir Orian, Elena Belova, Pavel Georgiev, Wing Hing Wong, Dayanne V Cornelio-Parra, Neta Erez
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
A hallmark of aging is loss of differentiated cell identity. AgedDrosophilamidgut differentiated enterocytes (ECs) lose their identity, impairing tissue homeostasis. To discover identity regulators, we performed an RNAi screen targeting ubiquitin-rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea7cb1fe37db07a204e8d95aca65517
https://doi.org/10.7554/elife.62312
https://doi.org/10.7554/elife.62312
Autor:
Salwa Danial, Lena Israitel, Gal Raz, Na'ama Flint Brodsly, Eliya Bitman-Lotan, Elena Belova, Ryan D Mohan, Amir Orian, Oksana Maksimenko, Dayanne V Cornelio-Parra, Pavel Georgiev, Wing Hing Wong, Todd E. Druley, Neta Erez
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8b718e0cbc66467fa4dd53fdd3d7d1f
https://doi.org/10.7554/elife.62312.sa2
https://doi.org/10.7554/elife.62312.sa2
Autor:
Vy T Ngo, Ada Thapa, Sarah R Rapp, Shea M Peterson, Veronica Cloud, Dayanne V Cornelio-Parra, Bwaar S Omer, Minh Q Nguyen, Ryan D Mohan, Austin O Dada
Publikováno v:
Journal of Visualized Experiments.
Nearly universal among organisms, circadian rhythms coordinate biological activity to earth's orbit around the sun. To identify factors creating this rhythm and to understand the resulting outputs, entrainment of model organisms to defined circadian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aae64732973293e358927ae589526ac
https://doi.org/10.3791/61176-v
https://doi.org/10.3791/61176-v
Autor:
Lauren G Shelton, Elaheh Momtahan, Richard A Pierce, Pedro Morales-Sosa, Daniel Holsapple, Jarrid L Jack, Sarah R Rapp, Skylar Martin-Brown, Michael P. Washburn, Ada Thapa, Ryan D Mohan, Edgardo Leiva, Laurence Florens, Tayla M Miller, Paige M Gerhart, Veronica Cloud, Sara A Miller
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd5c75549ff665fb93837b9709938515
https://doi.org/10.7554/elife.49677.017
https://doi.org/10.7554/elife.49677.017
Autor:
Lauren G Shelton, Tayla M Miller, Veronica Cloud, Ada Thapa, Sarah R Rapp, Laurence Florens, Pedro Morales-Sosa, Skylar Martin-Brown, Paige M Gerhart, Edgardo Leiva, Sara A Miller, Jarrid L Jack, Ryan D Mohan, Michael P. Washburn, Richard A Pierce, Daniel Holsapple, Elaheh Momtahan
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Ataxin-7 (Atxn7), a subunit of the SAGA chromatin remodeling complex, is subject to polyglutamine expansion at the amino terminus, causing spinocerebellar ataxia type 7 (SCA7), a progressive retinal and neurodegenerative disease. Within SAGA, the ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33ab4ab9e9d68ab73610beb4a2479ac
https://pubmed.ncbi.nlm.nih.gov/31348003
https://pubmed.ncbi.nlm.nih.gov/31348003
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1864:194630
The Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex is a critical regulator of gene expression and is highly conserved across species. Subunits of SAGA arrange into discrete modules with lysine aceyltransferase and deubiquitinase ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088a4050a67a7961dd8829ff105b752e
https://doi.org/10.1016/j.bbagrm.2020.194630
https://doi.org/10.1016/j.bbagrm.2020.194630