Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ryan D. Heselpoth"'
Publikováno v:
Biology, Vol 12, Iss 10, p 1277 (2023)
Bacteriophage endolysins degrade the bacterial peptidoglycan and are considered enzymatic alternatives to small-molecule antibiotics. In particular, the multimeric streptococcal endolysin PlyC has appealing antibacterial properties. However, a compre
Externí odkaz:
https://doaj.org/article/2cbd8116aed54495b8fe11f3f24006a5
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Most skin infections, including those complicating burns, are polymicrobial involving multiple causative bacteria. Add to this the fact that many of these organisms may be antibiotic-resistant, and a simple skin lesion or burn could soon become life-
Externí odkaz:
https://doaj.org/article/ffec277bf6ac4bd69745dd271bcae0a8
Autor:
Marek Harhala, Daniel C. Nelson, Paulina Miernikiewicz, Ryan D. Heselpoth, Beata Brzezicka, Joanna Majewska, Sara B. Linden, Xiaoran Shang, Aleksander Szymczak, Dorota Lecion, Karolina Marek-Bukowiec, Marlena Kłak, Bartosz Wojciechowicz, Karolina Lahutta, Andrzej Konieczny, Krystyna Dąbrowska
Publikováno v:
Viruses, Vol 10, Iss 11, p 638 (2018)
Bacteriophage-derived endolysins have gained increasing attention as potent antimicrobial agents and numerous publications document the in vivo efficacy of these enzymes in various rodent models. However, little has been documented about their safety
Externí odkaz:
https://doaj.org/article/0f4d7c9787af4ec68fe1a00469103f48
Autor:
James Fodor, Blake T. Riley, Kirill Tsyganov, Anne Geert Volbeda, Daniel C. Nelson, Kylie A Farrow, Brooke K. Hayes, Colin J. Jackson, Sheena McGowan, Sebastian S. Broendum, Ben E. Clifton, Ryan D. Heselpoth, Jeroen D. C. Codée, Felix Kraus, Daniel E. Williams, Nyssa Drinkwater, Ashley M. Buckle
Publikováno v:
Molecular Microbiology, 116(2), 397-415. WILEY
Endolysin enzymes from bacteriophage cause bacterial lysis by degrading the peptidoglycan cell wall. The streptococcal C1 phage endolysin PlyC, is the most potent endolysin described to date and can rapidly lyse group A, C, and E streptococci. PlyC i
Bacteriophage endolysins degrade the bacterial peptidoglycan and are considered enzymatic alternatives to small molecule antibiotics. In particular, the multimeric streptococcal endolysin PlyC has appealing antibacterial properties. However, a compre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031df307dcba7b491f7436108ddfbd4b
https://doi.org/10.1101/2022.01.06.475266
https://doi.org/10.1101/2022.01.06.475266
Publikováno v:
Frontiers in microbiology. 13
Most skin infections, including those complicating burns, are polymicrobial involving multiple causative bacteria. Add to this the fact that many of these organisms may be antibiotic-resistant, and a simple skin lesion or burn could soon become life-
Publikováno v:
Bacteriophages ISBN: 9783319405988
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bdff1ea54ba25f2615ada444c4f216
https://doi.org/10.1007/978-3-319-41986-2_34
https://doi.org/10.1007/978-3-319-41986-2_34
Autor:
Petr G. Leiman, Xiaoran Shang, Ryan D. Heselpoth, Sara B. Linden, Yan Zhou, Osnat Herzberg, Heng Luo, Julia Greenfield, Daniel C. Nelson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The genome of Escherichia coli O157:H7 bacteriophage vB_EcoM_CBA120 encodes four distinct tailspike proteins (TSPs). The four TSPs, TSP1-4, attach to the phage baseplate forming a branched structure. We report the 1.9 Å resolution crystal structure
Autor:
Lars F. Westblade, Neil S. Lipman, Christopher Cheleuitte-Nieves, Vincent A. Fischetti, Ryan D. Heselpoth
Publikováno v:
Comp Med
Corynebacterium bovis is the causative agent of Corynebacterium-associated hyperkeratosis in immunocompromised mice. The resulting skin pathology can be profound and can be associated with severe wasting, making the animals unsuitable for research. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca49ab65a90aceb65e1919001ff2d3f
https://europepmc.org/articles/PMC7446641/
https://europepmc.org/articles/PMC7446641/
The prevalence of multidrug-resistant Pseudomonas aeruginosa has stimulated development of alternative therapeutics. Bacteriophage peptidoglycan hydrolases, termed lysins, represent an emerging antimicrobial option for targeting Gram-positive bacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a26b5f4d7b9030f78a755cf5721d3f7
https://europepmc.org/articles/PMC6535517/
https://europepmc.org/articles/PMC6535517/