Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Ryan D. Heselpoth"'
Publikováno v:
Biology, Vol 12, Iss 10, p 1277 (2023)
Bacteriophage endolysins degrade the bacterial peptidoglycan and are considered enzymatic alternatives to small-molecule antibiotics. In particular, the multimeric streptococcal endolysin PlyC has appealing antibacterial properties. However, a compre
Externí odkaz:
https://doaj.org/article/2cbd8116aed54495b8fe11f3f24006a5
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Most skin infections, including those complicating burns, are polymicrobial involving multiple causative bacteria. Add to this the fact that many of these organisms may be antibiotic-resistant, and a simple skin lesion or burn could soon become life-
Externí odkaz:
https://doaj.org/article/ffec277bf6ac4bd69745dd271bcae0a8
Autor:
James Fodor, Blake T. Riley, Kirill Tsyganov, Anne Geert Volbeda, Daniel C. Nelson, Kylie A Farrow, Brooke K. Hayes, Colin J. Jackson, Sheena McGowan, Sebastian S. Broendum, Ben E. Clifton, Ryan D. Heselpoth, Jeroen D. C. Codée, Felix Kraus, Daniel E. Williams, Nyssa Drinkwater, Ashley M. Buckle
Publikováno v:
Molecular Microbiology, 116(2), 397-415. WILEY
Endolysin enzymes from bacteriophage cause bacterial lysis by degrading the peptidoglycan cell wall. The streptococcal C1 phage endolysin PlyC, is the most potent endolysin described to date and can rapidly lyse group A, C, and E streptococci. PlyC i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846e2ef7204d60bb22eabac1ed34cebe
https://doi.org/10.1111/mmi.14719
https://doi.org/10.1111/mmi.14719
Autor:
Yang Shen, Marilia Barros, Tarek Vennemann, D Travis Gallagher, Yizhou Yin, Sara B Linden, Ryan D Heselpoth, Dennis J Spencer, David M Donovan, John Moult, Vincent A Fischetti, Frank Heinrich, Mathias Lösche, Daniel C Nelson
Publikováno v:
eLife, Vol 5 (2016)
PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling intracellular Spy that often underlies refractory infections. We show that the PlyC holoenzyme, m
Externí odkaz:
https://doaj.org/article/aed840bf4c004cdc92ae7baba09aee44
Bacteriophage endolysins degrade the bacterial peptidoglycan and are considered enzymatic alternatives to small molecule antibiotics. In particular, the multimeric streptococcal endolysin PlyC has appealing antibacterial properties. However, a compre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031df307dcba7b491f7436108ddfbd4b
https://doi.org/10.1101/2022.01.06.475266
https://doi.org/10.1101/2022.01.06.475266
Autor:
Marek Harhala, Daniel C. Nelson, Paulina Miernikiewicz, Ryan D. Heselpoth, Beata Brzezicka, Joanna Majewska, Sara B. Linden, Xiaoran Shang, Aleksander Szymczak, Dorota Lecion, Karolina Marek-Bukowiec, Marlena Kłak, Bartosz Wojciechowicz, Karolina Lahutta, Andrzej Konieczny, Krystyna Dąbrowska
Publikováno v:
Viruses, Vol 10, Iss 11, p 638 (2018)
Bacteriophage-derived endolysins have gained increasing attention as potent antimicrobial agents and numerous publications document the in vivo efficacy of these enzymes in various rodent models. However, little has been documented about their safety
Externí odkaz:
https://doaj.org/article/0f4d7c9787af4ec68fe1a00469103f48
Publikováno v:
Frontiers in microbiology. 13
Most skin infections, including those complicating burns, are polymicrobial involving multiple causative bacteria. Add to this the fact that many of these organisms may be antibiotic-resistant, and a simple skin lesion or burn could soon become life-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75d16900882929745d11dc4242dbb87
https://pubmed.ncbi.nlm.nih.gov/35369520
https://pubmed.ncbi.nlm.nih.gov/35369520
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112939 (2014)
Alginate is a polysaccharide produced by certain seaweeds and bacteria that consists of mannuronic acid and guluronic acid residues. Seaweed alginate is used in food and industrial chemical processes, while the biosynthesis of bacterial alginate is a
Externí odkaz:
https://doaj.org/article/2d51a7de4b69456b89283fa17a1663e8
Autor:
Chen Chen, Patrick Bales, Julia Greenfield, Ryan D Heselpoth, Daniel C Nelson, Osnat Herzberg
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93156 (2014)
Bacteriophage tailspike proteins act as primary receptors, often possessing endoglycosidase activity toward bacterial lipopolysaccharides or other exopolysaccharides, which enable phage absorption and subsequent DNA injection into the host. Phage CBA
Externí odkaz:
https://doaj.org/article/e62f58243eb1407798520927eaa807e1
Publikováno v:
Bacteriophages ISBN: 9783319405988
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bdff1ea54ba25f2615ada444c4f216
https://doi.org/10.1007/978-3-319-41986-2_34
https://doi.org/10.1007/978-3-319-41986-2_34