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pro vyhledávání: '"Ryan D. Erwert"'
Autor:
Kristine T. Eiting, John M. Harlan, Ryan D. Erwert, Robert K. Winn, Joan C. Tupper, Douglas D. Bannerman
Publikováno v:
Microbial Pathogenesis. 35:87-93
Shiga toxin (Stx) has been implicated in the pathogenesis of several human and animal disease states. A key host target of Stx is the endothelial cell. Stx induces endothelial cell apoptosis through a mechanism that remains unknown. In the present re
Publikováno v:
Journal of Biological Chemistry. 277:40567-40574
Shiga-like toxin (SLT) has been implicated in the pathogenesis of hemolytic uremic syndrome and its attendant endothelial cell (EC) injury. Key serotypes of Escherichia coli produce SLT-1 in addition to another highly pro-inflammatory molecule, lipop
Publikováno v:
The Journal of biological chemistry. 277(10)
The vascular endothelium is a key target of circulating bacterial lipopolysaccharide (LPS). LPS elicits a wide array of endothelial responses, including the up-regulation of cytokines, adhesion molecules, and tissue factor, many of which are dependen