Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ryan D Pardy"'
Autor:
Ryan D Pardy, Katelyn A Walzer, Bethan A Wallbank, Jessica H Byerly, Keenan M O'Dea, Ian S Cohn, Breanne E Haskins, Justin L Roncaioli, Eleanor J Smith, Gracyn Y Buenconsejo, Boris Striepen, Christopher A Hunter
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1011820 (2024)
The production of IFN-γ is crucial for control of multiple enteric infections, but its impact on intestinal epithelial cells (IEC) is not well understood. Cryptosporidium parasites exclusively infect epithelial cells and the ability of interferons t
Externí odkaz:
https://doaj.org/article/22da1c042a9b49efbdc01edf4adb722e
Autor:
Alexis R Gibson, Adam Sateriale, Jennifer E Dumaine, Julie B Engiles, Ryan D Pardy, Jodi A Gullicksrud, Keenan M O'Dea, John G Doench, Daniel P Beiting, Christopher A Hunter, Boris Striepen
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010003 (2022)
Cryptosporidium is a leading cause of severe diarrhea and diarrheal-related death in children worldwide. As an obligate intracellular parasite, Cryptosporidium relies on intestinal epithelial cells to provide a niche for its growth and survival, but
Externí odkaz:
https://doaj.org/article/367de30753434b6e8aa16b952cf3306a
Autor:
Ryan D Pardy, Maaran M Rajah, Stephanie A Condotta, Nathan G Taylor, Selena M Sagan, Martin J Richer
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006184 (2017)
Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family. Although ZIKV infection is typically mild and self-limiting in healthy adults, infection has been associated with neurological symptoms such as Guillain-Barré syndrome, and a cau
Externí odkaz:
https://doaj.org/article/27737fbe6caf4c378de52f7d059680ef
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Infection with the apicomplexan parasite Cryptosporidium is a leading cause of diarrheal disease. Cryptosporidiosis is of particular importance in infants and shows a strong association with malnutrition, both as a risk factor and as a conse
Externí odkaz:
https://doaj.org/article/9590de29d671445582465bc47250772a
An Epidemic Zika Virus Isolate Drives Enhanced T Follicular Helper Cell and B Cell-Mediated Immunity
Autor:
Ryan D. Pardy, Maria E. Gentile, Alexandria M. Carter, Stephanie A. Condotta, Irah L. King, Martin J. Richer
Publikováno v:
J Immunol
Zika virus (ZIKV) is a mosquito-borne pathogen that recently caused a series of increasingly severe outbreaks. We previously demonstrated that, compared with a pre-epidemic isolate (ZIKVCDN), a Brazilian ZIKV isolate (ZIKVBR) possesses a novel capaci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3888c81792f4b769cd979f23d8dcd2
https://europepmc.org/articles/PMC8976755/
https://europepmc.org/articles/PMC8976755/
Autor:
Jeffrey Downey, Martin J. Richer, Maziar Divangahi, Stefanie F. Valbon, Esther Tarrab, Alain Lamarre, Ryan D. Pardy, Stephanie A. Condotta
Publikováno v:
ImmunoHorizons. 4:217-230
CD8+ T cell–mediated immunity is critical for host defense against viruses and requires mitochondria-mediated type I IFN (IFN-I) signaling for optimal protection. Cyclophilin D (CypD) is a mitochondrial matrix protein that modulates the mitochondri
Autor:
Alexis R. Gibson, Adam Sateriale, Jennifer E. Dumaine, Julie B. Engiles, Ryan D. Pardy, Jodi A. Gullicksrud, Keenan M. O’Dea, John G. Doench, Daniel P. Beiting, Christopher A. Hunter, Boris Striepen
Publikováno v:
PLoS pathogens. 18(5)
Cryptosporidiumis a leading cause of severe diarrhea and diarrheal-related death in children worldwide. As an obligate intracellular parasite,Cryptosporidiumrelies on intestinal epithelial cells to provide a niche for its growth and survival, but lit
Autor:
Stephanie A, Condotta, Jeffrey, Downey, Ryan D, Pardy, Stefanie F, Valbon, Esther, Tarrab, Alain, Lamarre, Maziar, Divangahi, Martin J, Richer
Publikováno v:
ImmunoHorizons. 4(4)
CD8
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Zika virus (ZIKV) has emerged as an important global health threat, with the recently acquired capacity to cause severe neurological symptoms and to persist within host tissues. We previously demonstrated that an early Asian lineage ZIKV isolate indu
Autor:
Ryan D. Pardy, Martin J. Richer
Publikováno v:
Cells, Vol 8, Iss 8, p 820 (2019)
Cells
Cells
CD4 and CD8 T cells are an important part of the host’s capacity to defend itself against viral infections. During flavivirus infections, T cells have been implicated in both protective and pathogenic responses. Given the recent emergence of Zika v