Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Ryan D, Sullivan"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9442 (2024)
Matrix metalloproteinases (MMPs) such as MMP-9, 3, and 2 degrade the cellular matrix and are believed to play a crucial role in ischemic stroke. We examined how the duration of ischemia (up to 4 h) and treatment with recombinant tissue plasminogen ac
Externí odkaz:
https://doaj.org/article/bfc0ae37e87849c0a0616587d8d3dbec
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/7a7ef71ef1c44048a1cd82c89110dd82
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/495d83d7a9b84bc19b46374a43d62de4
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 2016 (2022)
In heart failure with reduced ejection fraction (HFrEF), cardiogenic edema develops from impaired cardiac function, pathological remodeling, chronic inflammation, endothelial dysfunction, neurohormonal activation, and altered nitric oxide-related pat
Externí odkaz:
https://doaj.org/article/837e24e7aa664ad293dc2abc518c9d9c
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1874 (2022)
Symptomatic heart failure with reduced ejection fraction (HFrEF) is characterized by edema and chronic pathological activation of the classical renin–angiotensin–aldosterone system (RAAS). The soluble (pro)renin receptor (s(P)RR) is released into
Externí odkaz:
https://doaj.org/article/e6ba44113b4543b4869acd84ef25a52f
Publikováno v:
Diagnostics, Vol 12, Iss 4, p 989 (2022)
Pathological sodium-water retention or edema/congestion is a primary cause of heart failure (HF) decompensation, clinical symptoms, hospitalization, reduced quality of life, and premature mortality. Sodium-glucose cotransporter-2 inhibitors (SGLT-2i)
Externí odkaz:
https://doaj.org/article/93f83c295f4040b6b0d9033a72b0ad16
Autor:
Ryan D. Sullivan, Inna P. Gladysheva
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1103 (2022)
The prevalence of heart failure (HF) with reduced (r) and preserved (p) ejection fraction (EF) continues to rise globally despite current advances in diagnostics and improvements to medical management [...]
Externí odkaz:
https://doaj.org/article/c8180f2428d24d2dab7b51d44505b935
Autor:
Ranjana Tripathi, Ryan D. Sullivan, Tai-Hwang M. Fan, Radhika M. Mehta, Inna P. Gladysheva, Guy L. Reed
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4035 (2021)
Sodium restriction is often recommended in heart failure (HF) to block symptomatic edema, despite limited evidence for benefit. However, a low-sodium diet (LSD) activates the classical renin-angiotensin-aldosterone system (RAAS), which may adversely
Externí odkaz:
https://doaj.org/article/446661050e01445781a22a4b2e978e26
Autor:
Emmanuel M. Camors, Alyson H. Roth, Joseph R. Alef, Ryan D. Sullivan, Jason N. Johnson, Enkhsaikhan Purevjav, Jeffrey A. Towbin
Publikováno v:
Circulation
Background: Arrhythmogenic cardiomyopathy (ACM) is an inherited genetic disorder of desmosomal dysfunction, and PKP2 (plakophilin-2) has been reported to be the most common disease-causing gene when mutation-positive. In the early concealed phase, th
Autor:
Ranjana Tripathi, Ryan D. Sullivan, Tai-Hwang M. Fan, Radhika M. Mehta, Inna P. Gladysheva, Guy L. Reed
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5450 (2020)
Nearly one in three people in the U.S. will develop heart failure (HF), characterized by fluid retention (edema) in the lungs and elsewhere. This leads to difficult breathing, deterioration of physical capacity, restriction of normal activities and d
Externí odkaz:
https://doaj.org/article/37dc64b1c27e4ff787dcb83469bfbe3c