Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ryan Cvejkus"'
Autor:
Caterina Rosano, Thomas K. Karikari, Ryan Cvejkus, Bruna Bellaver, Pamela C. L. Ferreira, Joseph Zmuda, Victor Wheeler, Tharick A. Pascoal, Iva Miljkovic
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION Alzheimer's disease (AD) is increasing in the Caribbean, especially for persons of African ancestry (PAA) and women. However, studies have mostly utilized surveys without AD biomarkers. METHODS In the Tobago Health Study (n = 30
Externí odkaz:
https://doaj.org/article/c4436e9e5c31420db7a705bafce096b2
Autor:
Garan Jones, Katerina Trajanoska, Adam J. Santanasto, Najada Stringa, Chia-Ling Kuo, Janice L. Atkins, Joshua R. Lewis, ThuyVy Duong, Shengjun Hong, Mary L. Biggs, Jian’an Luan, Chloe Sarnowski, Kathryn L. Lunetta, Toshiko Tanaka, Mary K. Wojczynski, Ryan Cvejkus, Maria Nethander, Sahar Ghasemi, Jingyun Yang, M. Carola Zillikens, Stefan Walter, Kamil Sicinski, Erika Kague, Cheryl L. Ackert-Bicknell, Dan E. Arking, B. Gwen Windham, Eric Boerwinkle, Megan L. Grove, Misa Graff, Dominik Spira, Ilja Demuth, Nathalie van der Velde, Lisette C. P. G. M. de Groot, Bruce M. Psaty, Michelle C. Odden, Alison E. Fohner, Claudia Langenberg, Nicholas J. Wareham, Stefania Bandinelli, Natasja M. van Schoor, Martijn Huisman, Qihua Tan, Joseph Zmuda, Dan Mellström, Magnus Karlsson, David A. Bennett, Aron S. Buchman, Philip L. De Jager, Andre G. Uitterlinden, Uwe Völker, Thomas Kocher, Alexander Teumer, Leocadio Rodriguéz-Mañas, Francisco J. García, José A. Carnicero, Pamela Herd, Lars Bertram, Claes Ohlsson, Joanne M. Murabito, David Melzer, George A. Kuchel, Luigi Ferrucci, David Karasik, Fernando Rivadeneira, Douglas P. Kiel, Luke C. Pilling
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Muscle weakness has been associated with morbidity and mortality in older people. Here, the authors have investigated this trait further by performing a genome-wide meta-analysis of grip strength and Mendelian randomization to discover causal relatio
Externí odkaz:
https://doaj.org/article/c432b68fa4c74f79a795551d0b9372a0
Autor:
Iva Miljkovic, Ryan Cvejkus, Ping An, Bharat Thyagarajan, Kaare Christensen, Mary Wojczynski, Nicole Schupf, Joseph M. Zmuda
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 3 (2022)
Little is known about the risk of type 2 diabetes (T2D) among the offspring of individuals with exceptional longevity. We determined the incidence of and potential risk and protective factors for T2D among the offspring of probands and offspring’s
Externí odkaz:
https://doaj.org/article/0649a99d94c540d1b0fe2cbac1b2f653
Autor:
Rain Katz, Ryan Cvejkus, Bharat Thyagarajan, Jeffrey Carr, James G Terry, Sangeeta Nair, Victor Wheeler, Iva Miljkovic, Emma Barinas-Mitchell, Allison L Kuipers
Publikováno v:
Circulation. 147
During the aging process, the vasculature undergoes pathologic changes which are strongly associated with hypertension and future cardiovascular disease (CVD) risk. Previous work to identify protein biomarkers of these subclinical vascular changes, w
Autor:
Adrianna I Acevedo-Fontanez, Ryan Cvejkus, Marquis Hawkins, Allison L Kuipers, Megan M Marron, Joseph Zmuda, Emma Barinas-Mitchell, Victor Wheeler, Iva Miljkovic
Publikováno v:
Circulation. 147
Introduction: Sleep efficiency (or sleep continuity, i.e., a ratio of time spent sleeping to time spent in bed), is inversely associated with hypertension, impaired glucose metabolism, CVD risk, and mortality risk. Prolonged sedentary behavior and ph
Autor:
Adam Santanasto, Douglas Kiel, David Karasik, Ryan Cvejkus, Mary Biggs, Kathryn Lunetta, Joanne Murabito, Joseph Zmuda
Publikováno v:
Innovation in Aging. 6:214-215
Although measures of physical function such as walking speed and time to complete chair-rises are highly heritable, the genetic architecture underlying these phenotypes remains poorly defined. To identify potentially novel genes and pathways underlyi
Autor:
Adrianna Acevedo-Fontanez, Ryan Cvejkus, Allison Kuipers, Joseph Zmuda, Caterina Rosano, Iva Miljkovic
Publikováno v:
Innovation in Aging. 6:610-611
Objective Skeletal muscle adiposity (SMA) increases with aging and is recognized as a major risk factor for cardiometabolic diseases, disability, and mortality among older adults. Obesity is related to dementia and cognitive decline yet the relations
Autor:
IVA MILJKOVIC, RYAN CVEJKUS, PING AN, BHARAT THYAGARAJAN, JONAS MENGEL-FROM, MARY FEITOSA, ANISA N. BENBOURENANE, JOSEPH M. ZMUDA
Publikováno v:
Diabetes. 71
The epidemiology of prediabetes and its metabolomic features remain poorly characterized in the oldest old. Therefore, we characterized the serum lipidome in 635 nonagenarians and centenarians without type 2 diabetes (T2D) from the Long Life Family S
Autor:
Adrianna Acevedo-Fontanez, Ryan Cvejkus, joseph zmuda, Victor Wheeler, Caterina Rosano, Iva Miljkovic, Allison L Kuipers
Publikováno v:
Circulation. 145
Introduction: Skeletal muscle adipose tissue infiltration (i.e. myosteatosis) increases with aging, and is recognized as a major risk factor for cardio-metabolic diseases. While it is known that visceral adiposity is related to dementia and cognitive
Autor:
Adam Santanasto, Mary Wojczynski, Ryan Cvejkus, Bharat Thyagarajan, Kaare Christensen, Nicole Schupf, E Warwick Daw, Joseph Zmuda
Publikováno v:
Wojczynski, M, Cvejkus, R, Thyagarajan, B, Christensen, K, Schupf, N, Daw, E W, Zmuda, J & Santanasto, A 2021, ' Novel Positional Candidate Gene for Gait Speed Change in Older Adults: The Long Life Family Study ', Innovation in Aging, vol. 5, no. Suppl. 1, pp. 582-582 . https://doi.org/10.1093/geroni/igab046.2221
Gait speed is a heritable, robust predictor of longevity in older adults. Using genome-wide linkage analysis in 2379 individuals from 509 families (64±12 years; 45% men), we identified a locus on chromosome 16p linked to gait speed change over 7±1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96b5337c6af7ea7dfe6befbf9ba6f37
https://portal.findresearcher.sdu.dk/da/publications/e874336b-0384-4148-b12e-39cdb61e910e
https://portal.findresearcher.sdu.dk/da/publications/e874336b-0384-4148-b12e-39cdb61e910e