Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ryan C. Shean"'
Autor:
Yanpeng Li, Emilia Gordon, Ryan C. Shean, Amanda Idle, Xutao Deng, Alexander L. Greninger, Eric Delwart
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract CrAssphages are a diverse group of related phages detected in human feces where they are the most prevalent and abundant prokaryotic virus. CrAssphages’ cellular host has been identified as the anaerobic Bacteroides intestinalis. CrAssphag
Externí odkaz:
https://doaj.org/article/00493a7ec1c4467595d14ae13bb6f503
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background With sequencing technologies becoming cheaper and easier to use, more groups are able to obtain whole genome sequences of viruses of public health and scientific importance. Submission of genomic data to NCBI GenBank is a requirem
Externí odkaz:
https://doaj.org/article/5bfe9f52e0154e9a99b03e89b8b4d89e
Autor:
Sho Iketani, Ryan C. Shean, Marion Ferren, Negar Makhsous, Dolly B. Aquino, Amedee des Georges, Bert Rima, Cyrille Mathieu, Matteo Porotto, Anne Moscona, Alexander L. Greninger
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
IMPORTANCE Human parainfluenza virus 3 is an important cause of morbidity and mortality among infants, the immunocompromised, and the elderly. Using deep genomic sequencing of HPIV-3-positive clinical material and its subsequent viral isolate, we dis
Externí odkaz:
https://doaj.org/article/116787510a404c218ec29e3d5ebc31b9
Autor:
Samuel S. Minot, Vikas Peddu, Alexander L. Greninger, Keith R. Jerome, Arun K. Nalla, Meei Li Huang, Lasata Shrestha, Pavitra Roychoudhury, Hong Xie, Garrett A. Perchetti, Quynh Phung, Adam Reinhardt, Ryan C. Shean, Shriya B. Reddy
Publikováno v:
Clinical Chemistry
Background More than 2 months separated the initial description of SARS-CoV-2 and discovery of its widespread dissemination in the United States. Despite this lengthy interval, implementation of specific quantitative reverse transcription (qRT)-PCR-b
Autor:
Elizabeth A. Holmes, Gilbert E. Bautista, Dustin R. Long, Alexander L. Greninger, Pradeep K. Singh, Vikas Peddu, Ryan C. Shean, Stephen J. Salipante, Sara L. Rassoulian Barrett, Sumedha Ravishankar, Brad T. Cookson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
Scientific Reports
Scientific Reports
Diagnostically informative microbial cell-free DNA (cfDNA) can be detected from blood plasma during fulminant infections such as sepsis. However, the potential for DNA from airway pathogens to enter the circulation of cystic fibrosis (CF) patients du
Autor:
Shana R Burstein, Bert K. Rima, Jennifer Drew-Bear, Stefan Niewiesk, Michael Boeckh, Tara C. Marcink, Olivia Harder, Alexander L. Greninger, Michelle J. Lin, Matteo Porotto, Ksenia Rybkina, Ryan C. Shean, Negar Makhsous, Anne Moscona, Francesca T. Bovier
Publikováno v:
J Clin Invest
The capacity of respiratory viruses to undergo evolution within the respiratory tract raises the possibility of evolution under the selective pressure of the host environment or drug treatment. Long-term infections in immunocompromised hosts are pote
Autor:
Amanda Idle, Eric Delwart, Xutao Deng, Ryan C. Shean, Alexander L. Greninger, Emilia Gordon, Yanpeng Li
Publikováno v:
Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
CrAssphages are a diverse group of related phages detected in human feces where they are the most prevalent and abundant prokaryotic virus. CrAssphages’ cellular host has been identified as the anaerobic Bacteroides intestinalis. CrAssphage has als
With their small genomes, fast evolutionary rates, and clinical significance, viruses have long been fodder for studies of whole genome evolution. One common need in these studies is the analysis of viral evolution over time through longitudinal samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbb3b0a5cf91834d0324a916d1349a7
https://doi.org/10.1101/2019.12.17.879320
https://doi.org/10.1101/2019.12.17.879320
Autor:
Terry Stevens-Ayers, Janet A. Englund, Hu Xie, Ryan C. Shean, Alexander L. Greninger, Michael Boeckh, Wendy M. Leisenring, Alpana Waghmare, Chikara Ogimi, Jane Kuypers, Keith R. Jerome
Publikováno v:
The Journal of Infectious Diseases
Background Recent data suggest that human coronavirus (HCoV) pneumonia is associated with significant mortality in hematopoietic cell transplant (HCT) recipients. Investigation of risk factors for prolonged shedding and intrahost genome evolution may
Autor:
Jeong-Joong Yoon, Gregory R. Bluemling, Mart Toots, Alexander L. Greninger, Ryan C. Shean, Richard K. Plemper, Prabhakar Reddy, Alec H. Barrena, Robert M. Cox, Michael G Hart, Deborah G. Mitchell, Roland Plesker, George R. Painter, Alexander A. Kolykhalov, Zachary M. Sticher, Michael G. Natchus, Negar Makhsous
Publikováno v:
Sci Transl Med
Influenza viruses constitute a major health threat and economic burden globally, frequently exacerbated by pre-existing or rapidly emerging resistance to antiviral therapeutics. To address the unmet need of improved influenza therapy, we have created