Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ryan Baumgartner"'
Autor:
Ziyuan Song, Hailin Fu, Ryan Baumgartner, Lingyang Zhu, Kuo-Chih Shih, Yingchun Xia, Xuetao Zheng, Lichen Yin, Christophe Chipot, Yao Lin, Jianjun Cheng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
The folding-dependent catalytic behavior of enzymes is of fundamental biological importance, yet mechanistically underexplored. Here, the authors show that an α-helix, commonly found in proteins, can facilitate its own growth through the self-cataly
Externí odkaz:
https://doaj.org/article/d9c8265f36f1439fbf9f3949a2e2ae98
Autor:
Ziyuan Song, Rachael A. Mansbach, Hua He, Kuo-Chih Shih, Ryan Baumgartner, Nan Zheng, Xiaochu Ba, Yinzhao Huang, Deepak Mani, Yun Liu, Yao Lin, Mu-Ping Nieh, Andrew L. Ferguson, Lichen Yin, Jianjun Cheng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Hydrogen bonding plays a major role in determining the tridimensional structure of biopolymers. Here, the authors show that control over a polypeptide conformation can be achieved by altering the donor-acceptor properties of side-chain triazole units
Externí odkaz:
https://doaj.org/article/0d32e56919834d75b9cffc70076f783a
Publikováno v:
Macromolecules. 55:2041-2050
Autor:
Cecilia Leal, Ziyuan Song, Shen J. Dillon, Lin Feng, Hojun Kim, Yingfeng Yang, Kuan Ying Tseng, Jianjun Cheng, Lichen Yin, Ryan Baumgartner, Shixian Lv
Publikováno v:
Journal of the American Chemical Society. 142:8570-8574
Polypeptide micelles are widely used as biocompatible nanoplatforms but often suffer from their poor structural stability. Unimolecular polypeptide micelles can effectively address the structure instability issue, but their synthesis with uniform str
Autor:
Xuetao Zheng, Lichen Yin, Christophe Chipot, Yingchun Xia, Jianjun Cheng, Yao Lin, Ryan Baumgartner, Hailin Fu, Kuo-Chih Shih, Lingyang Zhu, Ziyuan Song
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Nature Communications
Nature Communications
Enzymes provide optimal three-dimensional structures for substrate binding and the subsequent accelerated reaction. Such folding-dependent catalytic behaviors, however, are seldom mechanistically explored with reduced structural complexity. Here, we
Autor:
Andrew L. Ferguson, Lichen Yin, Yao Lin, Chongyi Chen, Yingchun Xia, Xuefang Wang, Zhiyu Wang, Lazaro A. Pacheco, Ziyuan Song, Jiang Wang, Joaquín Rodríguez-López, Haoyuan Yan, Jianjun Cheng, Jingshu Hui, Tianrui Xue, Hailin Fu, Ryan Baumgartner
Publikováno v:
Proceedings of the National Academy of Sciences. 116:10658-10663
Ribozymes synthesize proteins in a highly regulated local environment to minimize side reactions caused by various competing species. In contrast, it is challenging to prepare synthetic polypeptides from the polymerization of N-carboxyanhydrides (NCA
Publikováno v:
Journal of the American Chemical Society. 141:8680-8683
Cooperative interactions and transitions are among the most important strategies utilized by biological systems to regulate a variety of physical and chemical processes. We report herein an auto-accelerated, rapid cooperative polymerization of N-carb
Autor:
Shixian, Lv, Hojun, Kim, Ziyuan, Song, Lin, Feng, Yingfeng, Yang, Ryan, Baumgartner, Kuan-Ying, Tseng, Shen J, Dillon, Cecilia, Leal, Lichen, Yin, Jianjun, Cheng
Publikováno v:
Journal of the American Chemical Society. 142(19)
Polypeptide micelles are widely used as biocompatible nanoplatforms but often suffer from their poor structural stability. Unimolecular polypeptide micelles can effectively address the structure instability issue, but their synthesis with uniform str
Autor:
Hua He, Yinzhao Huang, Yao Lin, Xiaochu Ba, Yun Liu, Deepak Mani, Ryan Baumgartner, Andrew L. Ferguson, Lichen Yin, Nan Zheng, Mu-Ping Nieh, Jianjun Cheng, Ziyuan Song, Kuo-Chih Shih, Rachael A. Mansbach
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Nature Communications
Nature Communications
Synthetic polypeptides have received increasing attention due to their ability to form higher ordered structures similar to proteins. The control over their secondary structures, which enables dynamic conformational changes, is primarily accomplished
Publikováno v:
ACS Macro Letters. 6:733-737
Model-based studies on helix–coil transition and folding cooperativity of synthetic polypeptides have contributed to the understanding of protein folding and stability and to the development of polypeptide-based functional materials. Polypeptide-co