Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ryan B Huang"'
Autor:
Ryan B Huang, Omolola Eniola-Adefeso
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31874 (2012)
BackgroundEndothelial cells (ECs) are continuously exposed to hemodynamic forces imparted by blood flow. While it is known that endothelial behavior can be influenced by cytokine activation or fluid shear, the combined effects of these two independen
Externí odkaz:
https://doaj.org/article/fc88ab988fca48c9b826d56508f81d2f
We describe an equibiaxial cell stretcher and hybrid, elastic membrane platform designed for dynamic imaging of cells on substrates with physiological stiffness undergoing cyclic stretch. Studies enabled by this device revealed that both substrate st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e03adc698399da37412cd09a26a47a
https://europepmc.org/articles/PMC5114158/
https://europepmc.org/articles/PMC5114158/
Publikováno v:
Biotechnology and Bioengineering. 110:999-1003
The ability to discriminate cell adhesion molecule expression between healthy and inflamed endothelium is critical for therapeutic intervention in many diseases. This study explores the effect of laminar flow on TNFα-induced E-selectin surface expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77c368a5113254698d9dc3f33fa238c
https://doi.org/10.1002/bit.24746
https://doi.org/10.1002/bit.24746
Publikováno v:
Annals of Biomedical Engineering. 37:737-748
LFA-1 and Mac-1 are the two integrins involved in the arrest and firm adhesion of neutrophils. LFA-1 plays a role in the early stage of cell arrest while Mac-1 stabilizes firm adhesion. Here, we further elucidated the kinetics of LFA-1 activation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3851ac3086b7c67a8ea343696f2a7063
https://doi.org/10.1007/s10439-009-9647-8
https://doi.org/10.1007/s10439-009-9647-8
Autor:
Supriya Mocherla, Phapanin Charoenphol, Michael J. Heslinga, Omolola Eniola-Adefeso, Ryan B. Huang
Publikováno v:
Molecular membrane biology. 27(7)
Vascular-targeted drug delivery systems could provide more efficient and effective pharmaceutical interventions for treating a variety of diseases including cardiovascular, pulmonary, inflammatory, and malignant disorders. However, several factors mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef6084c2a5568dafe9b3b6e7261f8c5
https://pubmed.ncbi.nlm.nih.gov/20615080
https://pubmed.ncbi.nlm.nih.gov/20615080
Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers
Publikováno v:
Biomaterials. 31(6)
Targeting of drug carriers to the vascular wall is of interest for localized delivery of therapeutics in many human diseases. Nanometer-sized spherical particles are widely proposed for use as carriers for vascular targeting, yet very little evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52190f6c8671fe700f6743068299c00a
https://pubmed.ncbi.nlm.nih.gov/19954839
https://pubmed.ncbi.nlm.nih.gov/19954839
Publikováno v:
Biotechnology and bioengineering. 101(2)
Most embryonic stem (ES) cell research is performed with a gas phase oxygen partial pressure (pO 2 ) of 142 mmHg, whereas embryonic cells in early development are exposed to pO 2 values of 0-30 mmHg. To understand effects of these differences, we stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14dc28c5f6080ac2c202c1148d99ea0
https://pubmed.ncbi.nlm.nih.gov/18727033
https://pubmed.ncbi.nlm.nih.gov/18727033
Autor:
Omolola Eniola-Adefeso, Ryan B. Huang
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31874 (2012)
PLoS ONE
PLoS ONE
BackgroundEndothelial cells (ECs) are continuously exposed to hemodynamic forces imparted by blood flow. While it is known that endothelial behavior can be influenced by cytokine activation or fluid shear, the combined effects of these two independen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3331c47414c5550c02bdda63df49b0
https://doi.org/10.1371/journal.pone.0031874
https://doi.org/10.1371/journal.pone.0031874