Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ryan Albee"'
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c92e1bb1db780edec3d72180dd826a8f
https://doi.org/10.1096/fasebj.2018.32.1_supplement.415.3
https://doi.org/10.1096/fasebj.2018.32.1_supplement.415.3
Autor:
Cheryl E. Rockwell, Ryan Albee, Kate M. O’Brien, Keara Towery, Akie Mochizuki, Aaron Pace, Aaron K. Chow, Kara Kelly, Bryan L. Copple, Katherine Roth, James P. Luyendyk
Publikováno v:
The Journal of Immunology. 192:3847-3857
Hypoxia-inducible factor-1α (HIF-1α) is activated in hepatic stellate cells (HSCs) by hypoxia and regulates genes important for tissue repair. Whether HIF-1α is activated in HSCs after acute injury and contributes to liver regeneration, however, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5ff8d34d56f1f2d1cdcd39507c50111
https://doi.org/10.4049/jimmunol.1303195
https://doi.org/10.4049/jimmunol.1303195
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 349:185-191
Trovafloxacin (TVX) is a fluoroquinolone antibiotic known to cause idiosyncratic, drug-induced liver injury (IDILI) in humans. The mechanism underlying this toxicity remains unknown. Previously, an animal model of IDILI in mice revealed that TVX syne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18088ac64a0bfb0600c9ce6be91a429
https://doi.org/10.1124/jpet.113.211276
https://doi.org/10.1124/jpet.113.211276
Publikováno v:
The FASEB Journal. 29
When cells in the liver are damaged or killed by trauma, macrophages become activated to release cytokines and phagocytose dead cell debris, which facilitates liver repair. The mechanisms that regu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::697f893776215901fa3b26b2b820beaa
https://doi.org/10.1096/fasebj.29.1_supplement.53.5
https://doi.org/10.1096/fasebj.29.1_supplement.53.5
Autor:
Lynda Letzig, Patricia E. Ganey, Michael A. Scott, Laura P. James, Ryan Albee, Robert A. Roth, John P. Buchweitz, Kazuhisa Miyakawa, Andreas F. Lehner
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 354(2)
Mouse hepatic parenchymal cells (HPCs) have become the most frequently used in vitro model to study mechanisms of acetaminophen (APAP)-induced hepatotoxicity. It is universally accepted that APAP hepatocellular injury requires bioactivation by cytoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3e2caafbda8d2bfef9f00d7fb3d215
https://pubmed.ncbi.nlm.nih.gov/26065700
https://pubmed.ncbi.nlm.nih.gov/26065700
Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice
Autor:
Kazuhisa Miyakawa, Nikita Joshi, Patricia E. Ganey, Christina Brandenberger, Michael A. Scott, Mitchell R. McGill, James P. Luyendyk, Hartmut Jaeschke, Robert A. Roth, Bradley P. Sullivan, Ryan Albee
Publikováno v:
Blood. 126(15)
Acetaminophen (APAP)-induced liver injury in humans is associated with robust coagulation cascade activation and thrombocytopenia. However, it is not known whether coagulation-driven platelet activation participates in APAP hepatotoxicity. Here, we f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb303e9e279369f0933ad8b526d3de2
https://pubmed.ncbi.nlm.nih.gov/26450954
https://pubmed.ncbi.nlm.nih.gov/26450954