Small-Angle Scattering as a Structural Probe for Nucleic Acid Nanoparticles (NANPs) in a Dynamic Solution Environment

Autor: Ryan C. Oliver, Lewis A. Rolband, Alanna M. Hutchinson-Lundy, Kirill A. Afonin, Joanna K. Krueger

Publikováno v: Nanomaterials, Vol 9, Iss 5, p 681 (2019)

Nucleic acid-based technologies are an emerging research focus area for pharmacological and biological studies because they are biocompatible and can be designed to produce a variety of scaffolds at the nanometer scale. The use of nucleic acids (ribo

Externí odkaz: https://doaj.org/article/0ba97b97aaa54081bc2b4937865f0ead

Assembly of capsids from hepatitis B virus core protein progresses through highly populated intermediates in the presence and absence of RNA

Autor: Ryan C. Oliver, Ingemar André, Najet Mahmoudi, Seyed Morteza Najibi, Lise Arleth, Martin Nors Pedersen, Wojciech Potrzebowski

Publikováno v: 'ACS Nano ', vol: 14, pages: 10226-10238 (2020)
ACS Nano
Oliver, R C, Potrzebowski, W, Najibi, S M, Pedersen, M N, Arleth, L, Mahmoudi, N & Andre, I 2020, ' Assembly of Capsids from Hepatitis B Virus Core Protein Progresses through Highly Populated Intermediates in the Presence and Absence of RNA ', ACS Nano, vol. 14, no. 8, pp. 10226-10238 . https://doi.org/10.1021/acsnano.0c03569

The genetic material of viruses is protected by protein shells that are assembled from a large number of subunits in a process that is efficient and robust. Many of the mechanistic details underpinning efficient assembly of virus capsids are still un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb25d3485836ecb98513db40892147e
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:56200

Peptide-conjugated phosphorodiamidate morpholino oligomers for the treatment of late-onset Pompe disease

Autor: Ryan A. Oliver, Meghan E. Ahern, Annika B. Malmberg, Kevin J. Kim

Publikováno v: Molecular Genetics and Metabolism. 135:S92

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60b64fec96fb6a41e64f84fb270f296e
https://doi.org/10.1016/j.ymgme.2021.11.239

Identification and Characterization of the Sulfazecin Monobactam Biosynthetic Gene Cluster

Autor: Ryan A. Oliver, Rongfeng Li, Craig A. Townsend

Publikováno v: Cell Chemical Biology. 24:24-34

The monobactams, exemplified by the natural product sulfazecin, are the only class of β-lactam antibiotics not inactivated by metallo-β-lactamases, which confer bacteria with extended-spectrum β-lactam resistance. We screened a transposon mutagene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3550f00a271126c86134080866bbbb33
https://doi.org/10.1016/j.chembiol.2016.11.010

The Fluidity of Phosphocholine and Maltoside Micelles and the Effect of CHAPS

Autor: Marissa Kieber, Sarah B. Nyenhuis, Linda Columbus, D. Peter Tieleman, Ryan C. Oliver, Tomihiro Ono

Publikováno v: Biophys J

The dynamics of phosphocholine and maltoside micelles, detergents frequently used for membrane protein structure determination, were investigated using electron paramagnetic resonance of spin probes doped into the micelles. Specifically, phosphocholi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42301e68a575b3eb9cf1d551e32147da
https://europepmc.org/articles/PMC6506624/