Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Ryan A. Koppes"'
Autor:
Adam J. Bindas, Kyla N. Nichols, Nicole J. Roth, Ryan Brady, Abigail N. Koppes, Ryan A. Koppes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Recent evidence implicates a gut-first pathogenesis in the enteric nervous system (ENS) within a portion of PD patients, yet in vitro investigations have primarily focused on the central nervous system. Here, the preformed fibril (PFF) PD mo
Externí odkaz:
https://doaj.org/article/c0eb52dabc4c404293914bb73aa6b033
Publikováno v:
iScience, Vol 21, Iss , Pp 521-548 (2019)
Recent advancements in electronic materials and subsequent surface modifications have facilitated real-time measurements of cellular processes far beyond traditional passive recordings of neurons and muscle cells. Specifically, the functionalization
Externí odkaz:
https://doaj.org/article/73597f9ba4884bbda7b4bd041b6f92af
Publikováno v:
APL Bioengineering, Vol 5, Iss 1, Pp 011507-011507-19 (2021)
The ability of mammalian neural stem cells (NSCs) to self-renew and differentiate throughout adulthood has made them ideal to study neurogenesis and attractive candidates for neurodegenerative disease therapies. In the adult mammalian brain, NSCs are
Externí odkaz:
https://doaj.org/article/6d1082ce421c4875bffb247e9abd6c50
Publikováno v:
Advanced Biology. 7
Publikováno v:
Advanced Biology. 7
Excitation-coupling (ECC) is paramount for coordinated contraction to maintain sufficient cardiac output. The study of ECC regulation has primarily been limited to cardiomyocytes (CMs), which conduct voltage waves via calcium fluxes from one cell to
Autor:
Avery Cluff, David Diaz Vera, Christian Gagnon, Ryan A. Koppes, Abigail N. Koppes, Daniel M. Ventre
Publikováno v:
Journal of Neuroscience Research. 99:374-391
Satisfactory treatment of peripheral nerve injury (PNI) faces difficulties owing to the intrinsic biological barriers in larger injuries and invasive surgical interventions. Injury gaps >3 cm have low chances of full motor and sensory recovery, and t
Autor:
Ryan A. Koppes, Will Lake, Abigail N. Koppes, Shashi K. Murthy, David T. Breault, Eric Stas, Sanjin Hosic
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: The intestinal epithelium contains specialized cells including enterocytes, goblet, Paneth, enteroendocrine, and stem cells. Impaired barrier integrity in Inflammatory Bowel Disease is characterized by elevated levels of pro-inflammator
Publikováno v:
Current Opinion in Biomedical Engineering. 14:42-51
Microphysiological systems (MPSs) of the nervous system provide physiologically relevant models for studying disease and development. Historically, sourcing of neurons was a limitation of in vitro models. Recently, MPSs have been fabricated that use
Autor:
Yuan Li, An Qi Zhang, Abigail N. Koppes, Sanjin Hosic, Jessica Snyder, Ryan A. Koppes, Chia-Ming Wang, Joshua Luchan, Rebecca Lyn Carrier
Publikováno v:
Annals of Biomedical Engineering. 48:1916-1940
The barrier functions of the gastrointestinal tract rely in large part on a single layer of columnar intestinal epithelial cells. These epithelial cells are mediators of intestinal homeostasis, regulating and communicating biochemical signals between
Publikováno v:
iScience, Vol 21, Iss, Pp 521-548 (2019)
iScience
iScience
Recent advancements in electronic materials and subsequent surface modifications have facilitated real-time measurements of cellular processes far beyond traditional passive recordings of neurons and muscle cells. Specifically, the functionalization