Zobrazeno 1 - 10
of 328
pro vyhledávání: '"Ryan A. Johnston"'
Autor:
Neil C. Dalvie, Christopher A. Naranjo, Sergio A. Rodriguez-Aponte, Ryan S. Johnston, J. Christopher Love
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-11 (2022)
Abstract Background Komagataella phaffii is a commonly used alternative host for manufacturing therapeutic proteins, in part because of its ability to secrete recombinant proteins into the extracellular space. Incorrect processing of secreted protein
Externí odkaz:
https://doaj.org/article/fe5f46864deb41008b8adbcc78977c74
Autor:
Sakshi Bajoria, Kawaljit Kaur, Ozan S. Kumru, Greta Van Slyke, Jennifer Doering, Hayley Novak, Sergio A. Rodriguez Aponte, Neil C. Dalvie, Christopher A. Naranjo, Ryan S. Johnston, Judith Maxwell Silverman, Harry Kleanthous, J. Christopher Love, Nicholas J. Mantis, Sangeeta B. Joshi, David B. Volkin
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 5 (2022)
Low-cost, refrigerator-stable COVID-19 vaccines will facilitate global access and improve vaccine coverage in low- and middle-income countries. To this end, subunit-based approaches targeting the receptor-binding domain (RBD) of SARS-CoV-2 Spike prot
Externí odkaz:
https://doaj.org/article/35022f23ff944bc2b948e4fb228bed37
RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge
Autor:
Ting Y. Wong, Brynnan P. Russ, Katherine S. Lee, Olivia A. Miller, Jason Kang, Melissa Cooper, Michael T. Winters, Sergio A. Rodriguez-Aponte, Neil C. Dalvie, Ryan S. Johnston, Nathaniel A. Rader, Zeriel Y. Wong, Holly A. Cyphert, Ivan Martinez, Umesh Shaligram, Saurabh Batwal, Rakesh Lothe, Rahul Chandrasekaran, Gaurav Nagar, Meghraj Rajurkar, Harish Rao, Justin R. Bevere, Mariette Barbier, J. Christopher Love, F. Heath Damron
Publikováno v:
mSphere, Vol 7, Iss 4 (2022)
ABSTRACT The ongoing COVID-19 pandemic has contributed largely to the global vaccine disparity. Development of protein subunit vaccines can help alleviate shortages of COVID-19 vaccines delivered to low-income countries. Here, we evaluated the effica
Externí odkaz:
https://doaj.org/article/7e59b729158c4ad3a17a90eef5a55568
Autor:
Mahali S. Morgan, Kexin Yan, Thuy T. Le, Ryan A. Johnston, Alberto A. Amarilla, David A. Muller, Christopher L. D. McMillan, Naphak Modhiran, Daniel Watterson, James R. Potter, Julian D.J. Sng, Mary Lor, Devina Paramitha, Ariel Isaacs, Alexander A. Khromykh, Roy A. Hall, Andreas Suhrbier, Daniel J. Rawle, Jody Hobson-Peters
Publikováno v:
Viruses, Vol 15, Iss 1, p 139 (2022)
The global coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spawned an ongoing demand for new research reagents and interventions. Herein we describe a panel of monoclonal ant
Externí odkaz:
https://doaj.org/article/82d6e8999d344525a4e59c50bacc8174
Autor:
Sergio A. Rodriguez‐Aponte, Christopher A. Naranjo, Ryan S. Johnston, Neil C. Dalvie, Laura E. Crowell, Sakshi Bajoria, Ozan S. Kumru, Sangeeta B. Joshi, David B. Volkin, J. Christopher Love
Publikováno v:
Biotechnology and Bioengineering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a61cd6f1594d836a91605f0d7ada5c
https://doi.org/10.1002/bit.28385
https://doi.org/10.1002/bit.28385
Autor:
Sergio A. Rodriguez-Aponte, Neil C. Dalvie, Ting Y. Wong, Ryan S. Johnston, Christopher A. Naranjo, Sakshi Bajoria, Ozan S. Kumru, Kawaljit Kaur, Brynnan P. Russ, Katherine S. Lee, Holly A. Cyphert, Mariette Barbier, Harish D. Rao, Meghraj P. Rajurkar, Rakesh R. Lothe, Umesh S. Shaligram, Saurabh Batwal, Rahul Chandrasekaran, Gaurav Nagar, Harry Kleanthous, Sumi Biswas, Justin R. Bevere, Sangeeta B. Joshi, David B. Volkin, F. Heath Damron, J. Christopher Love
There is a continued need for sarbecovirus vaccines that can be manufactured and distributed in low- and middle-income countries (LMICs). Subunit protein vaccines are manufactured at large scales at low costs, have less stringent temperature requirem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ccf32630a7ae84f2a75bcce081265e
https://doi.org/10.1101/2022.09.14.507842
https://doi.org/10.1101/2022.09.14.507842
Autor:
Jocelyn S. Steinfeld, Keith K. Ameyaw, Christopher G. Wood, Ryan M. Johnston, Ana J. Johnson Escauriza, Emma G. Torija, Kiloni Quiles, Kavita Venkataramani, Jessica N. MacNeil, Kellee R. Siegfried
The double-sex and mab3 related transcription factor (dmrt) gene family has conserved roles in sex determination and gonad development across metazoans. In zebrafish, dmrt1 was previously shown to function in male sex-determination and testes develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82d7fb01339e69e6519a5872809a6ee1
https://doi.org/10.1101/2022.08.28.505603
https://doi.org/10.1101/2022.08.28.505603
Autor:
J. Christopher Love, Laura E. Crowell, Umesh Shaligram, Neil C. Dalvie, Rakesh R Lothe, Christopher A Naranjo, Seraphin Castelino, Ryan S Johnston, Charles A. Whittaker, Meghraj P Rajurkar, Harish D Rao, Mary Kate Tracey, Andrew M. Biedermann, Sergio A. Rodriguez-Aponte
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Prevention of COVID-19 on a global scale will require the continued development of high-volume, low-cost platforms for the manufacturing of vaccines to supply ongoing demand. Vaccine candidates based on recombinant protein subunits remain important b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613b82185e05456fbd6b807c8e291c47
https://pubmed.ncbi.nlm.nih.gov/33880471
https://pubmed.ncbi.nlm.nih.gov/33880471
Autor:
Charles A. Whittaker, Aiquan Chang, J. Christopher Love, Hanne Leth Andersen, Lisa H. Tostanoski, Ozan S. Kumru, Nicolas Collin, Brooke Fiala, Megan Lok, Neil P. King, Brittany L. Hartwell, Danielle L Camp, Joseph R. Brady, Mary Kate Tracey, Andrew M. Biedermann, Kristen A Rodrigues, Harry Kleanthous, Jing Yang Wang, Katherine McMahan, Judith M. Silverman, Murillo Silva, Sergio A. Rodriguez-Aponte, David B. Volkin, Darrell J. Irvine, Thomas Courant, Maciel Porto, Sangeeta B. Joshi, Jingyou Yu, Patrice M. Dubois, Swagata Kar, Dan H. Barouch, Ashley A. Lemnios, Lauren Carter, Christopher A Naranjo, Ryan S Johnston, Celia Lebas, Dongsoo Yun, Neil C. Dalvie, Carl Walkey, Natalie Brunette, Laura E. Crowell, Kerry R. Love, Kawaljit Kaur, Mark G. Lewis
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Global containment of COVID-19 still requires accessible and affordable vaccines for low- and middle-income countries (LMICs).1 Recently approved vaccines provide needed interventions, albeit at prices that may limit their global access.2 Subunit vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f708622e17cebfff295c987cf72435
https://doi.org/10.1073/pnas.2106845118
https://doi.org/10.1073/pnas.2106845118
Autor:
Neil C, Dalvie, Andrew M, Biedermann, Sergio A, Rodriguez-Aponte, Christopher A, Naranjo, Harish D, Rao, Meghraj P, Rajurkar, Rakesh R, Lothe, Umesh S, Shaligram, Ryan S, Johnston, Laura E, Crowell, Seraphin, Castelino, Mary Kate, Tracey, Charles A, Whittaker, J Christopher, Love
Publikováno v:
Biotechnology and Bioengineering
Prevention of COVID‐19 on a global scale will require the continued development of high‐volume, low‐cost platforms for the manufacturing of vaccines to supply ongoing demand. Vaccine candidates based on recombinant protein subunits remain impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e13ddee7f526f0dd15890f8f18331d0c
https://pubmed.ncbi.nlm.nih.gov/34780057
https://pubmed.ncbi.nlm.nih.gov/34780057