Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ryan A. Cabot"'
Autor:
Sarah M. Innis, Ryan A. Cabot
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Given their physiological similarities to humans, pigs are increasingly used as model organisms in human-oriented biomedical studies. Additionally, their value to animal agriculture across the globe has led to the development of n
Externí odkaz:
https://doaj.org/article/02b52a5e84c84daea2a48beba4f1c5bd
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38990 (2012)
Specialized trafficking systems in eukaryotic cells serve a critical role in partitioning intracellular proteins between the nucleus and cytoplasm. Cytoplasmic proteins (including chromatin remodeling enzymes and transcription factors) must gain acce
Externí odkaz:
https://doaj.org/article/028bd94dbec0485dba2c282f73d893e1
Publikováno v:
Molecular Reproduction and Development. 84:1250-1256
Mammalian embryos undergo dramatic epigenetic remodeling that can have a profound impact on both gene transcription and overall embryo developmental competence. Members of the SWI/SNF (Switch/Sucrose non-fermentable) family of chromatin-remodeling co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0beb72d576d5db320378d5518f6dda
https://doi.org/10.1002/mrd.22924
https://doi.org/10.1002/mrd.22924
Publikováno v:
Molecular Reproduction and Development
In vitro embryo production is an established method for both humans and animals, but is fraught with inferior development and health issues in offspring born after in vitro fertilization procedures. Analysis of epigenetic changes caused by exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f765f7d1f954dadef110f001fecc093
http://europepmc.org/articles/PMC5760298
http://europepmc.org/articles/PMC5760298
Autor:
Birgit Cabot, Ryan A Cabot
Publikováno v:
Reproduction (Cambridge, England). 155(3)
The mammalian embryo undergoes a dramatic amount of epigenetic remodeling during the first week of development. In this review, we discuss several epigenetic changes that happen over the course of cleavage development, focusing on covalent marks (e.g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2d38de3ee447311e364f608c92cfac
https://pubmed.ncbi.nlm.nih.gov/29339454
https://pubmed.ncbi.nlm.nih.gov/29339454
Autor:
Christopher A. Bidwell, Sean C. Newcomer, Ryan A. Cabot, Kallie B. Foust, Martin Bahls, Jeremy N. Marchant-Forde, Ryan D. Sheldon, M. Harold Laughlin, Kerry A. Clifford, Emily Breslin, Pardis Taheripour
Publikováno v:
Experimental Physiology. 99:205-219
The intrauterine environment is influenced by maternal behaviour and programmes atherosclerotic disease susceptibility in offspring. The aim of this investigation was to test the hypothesis that mothers' exercise during pregnancy improves endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54105ca0f8180e2a7b31843feeb95802
https://doi.org/10.1113/expphysiol.2013.075978
https://doi.org/10.1113/expphysiol.2013.075978
Publikováno v:
Animal Reproduction Science. 133:198-204
Chromatin-modifying complexes serve essential functions during mammalian embryonic development. Polycomb group proteins EED, SUZ12, and EZH2 have been shown to mediate methylation of the lysine 27 residue of histone protein H3 (H3K27), an epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b303eb4933f78bca4744301fcaf4c1
https://doi.org/10.1016/j.anireprosci.2012.07.006
https://doi.org/10.1016/j.anireprosci.2012.07.006
Publikováno v:
Molecular Reproduction and Development. 76:1033-1042
Histone methylation plays an important role in regulating chromatin structure and gene expression. Methylation of the lysine residue 27 of histone H3 (H3K27) is an epigenetic mark that is closely linked with transcriptional repression; global pattern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1926335cea87336ca26b35e798df29e
https://doi.org/10.1002/mrd.21061
https://doi.org/10.1002/mrd.21061
Publikováno v:
Molecular Reproduction and Development. 75:766-776
Somatic cell nuclear transfer (SCNT) still retains important limitations. Impaired epigenetic reprogramming is considered responsible for altered gene expression and developmental failure in SCNT-derived embryos. After nuclear transfer the donor cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea64f1e51ded0d376b5690d6efed02e
https://doi.org/10.1002/mrd.20818
https://doi.org/10.1002/mrd.20818
Publikováno v:
Gene. 326:59-66
All eukaryotes share a common nuclear infrastructure, in which DNA is packaged into nucleosomal chromatin. Its functional states, in particular the accessibility of the chromatin fiber to trans-acting factors, are determined by two classes of evoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9971a91090091125a960b7a903089222
https://doi.org/10.1016/j.gene.2003.09.053
https://doi.org/10.1016/j.gene.2003.09.053