Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ryan A Zander"'
Autor:
Fionna A Surette, Jenna J Guthmiller, Lei Li, Alexandria J Sturtz, Rahul Vijay, Rosemary L Pope, Brandon L McClellan, Angela D Pack, Ryan A Zander, Peng Shao, Linda Yu-Ling Lan, Daniel Fernandez-Ruiz, William R Heath, Patrick C Wilson, Noah S Butler
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009288 (2021)
Immunity against malaria depends on germinal center (GC)-derived antibody responses that are orchestrated by T follicular helper (TFH) cells. Emerging data show that the regulatory cytokine IL-10 plays an essential role in promoting GC B cell respons
Externí odkaz:
https://doaj.org/article/a3b5ae33d8a345c092abcc9b69246885
Autor:
Ryan A Zander, Jenna J Guthmiller, Amy C Graham, Rosemary L Pope, Bradly E Burke, Daniel J J Carr, Noah S Butler
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005945 (2016)
CD4 T cell-dependent antibody responses are essential for limiting Plasmodium parasite replication and the severity of malaria; however, the factors that regulate humoral immunity during highly inflammatory, Th1-biased systemic infections are poorly
Externí odkaz:
https://doaj.org/article/4585d5bb64b94ec8ac641cfd366f0297
Autor:
Ryan A Zander, David Schauder, Gang Xin, Christine Nguyen, Xiaopeng Wu, Allan J Zajac, Weiguo Cui
Publikováno v:
The Journal of Immunology. 204:247.1-247.1
CD8 T cells responding to chronic viral infection can be classified into two major subsets, with a TCF-1+ subset serving as a self-renewing progenitor population that can give rise to a more terminally exhausted PD-1hi subset. However, whether additi
Autor:
Amy C Graham, Nyamekye Obeng-Adjei, Jenna J Guthmiller, Ryan A Zander, Elizabeth A Wohlfert, Peter D Crompton, Noah S Butler
Publikováno v:
The Journal of Immunology. 196:134.12-134.12
Plasmodium infections and the disease malaria remain global health emergencies. CD4 T cells are essential for coordinating protective immunity against Plasmodium infection and promoting parasite clearance, yet long-lived immunity is rarely acquired.
Publikováno v:
The Journal of Immunology. 196:134.4-134.4
Plasmodium infections cause malaria, which remains a global public health crisis. Germinal center derived anti-Plasmodium antibody responses are essential for control of blood-stage parasite replication and clearance. However, antibody responses are
Autor:
Ryan A. Zander, Rahul Vijay, Angela D. Pack, Jenna J. Guthmiller, Amy C. Graham, Scott E. Lindner, Ashley M. Vaughan, Stefan H.I. Kappe, Noah S. Butler
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1839-1852 (2017)
Summary: Effector T cells exhibiting features of either T helper 1 (Th1) or T follicular helper (Tfh) populations are essential to control experimental Plasmodium infection and are believed to be critical for resistance to clinical malaria. To determ
Externí odkaz:
https://doaj.org/article/44e6807e52be496882cdd17a8dc72497