Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Ryan A Denu"'
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 1071-1086 (2024)
Introduction: Vogt-Koyanagi-Harada (VKH) disease is a multisystem syndrome characterized by uveitis and exudative retinal detachments in the absence of ocular trauma or surgery. Neurological and cutaneous manifestations can also occur. Prior case rep
Externí odkaz:
https://doaj.org/article/edce95f67d1d4be68f7e23676e50a85d
Publikováno v:
The Clinical Respiratory Journal, Vol 18, Iss 3, Pp n/a-n/a (2024)
Abstract Introduction Pleural effusions are known to occur in many cases of COVID‐19. Data on typical characteristics of COVID‐19‐associated pleural effusions are limited. The goal of this project was to characterize the pleural fluid from pati
Externí odkaz:
https://doaj.org/article/7f56288805c0482f88752693b9733e75
Autor:
Daniel R. Matson, Ryan A. Denu, Lauren M. Zasadil, Mark E. Burkard, Beth A. Weaver, Christopher Flynn, P. Todd Stukenberg
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Targeting Protein for Xenopus Kinesin Like Protein 2 (TPX2) is a microtubule associated protein that functions in mitotic spindle assembly. TPX2 also localizes to the nucleus where it functions in DNA damage repair during S-phase.
Externí odkaz:
https://doaj.org/article/aeb3375ffa3047b2a1cbf2d36199aaec
Autor:
Ashok Singh, Ryan A. Denu, Serena K. Wolfe, Jamie M. Sperger, Jennifer Schehr, Tessa Witkowsky, Karla Esbona, Richard J. Chappell, Beth A. Weaver, Mark E. Burkard, Joshua M. Lang
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1898-1909 (2020)
Centrosome amplification (CA) is a common phenomenon in cancer, promotes genomic stability and cancer evolution, and has been reported to promote metastasis. CA promotes a stochastic gain/loss of chromosomes during cell division, known as chromosomal
Externí odkaz:
https://doaj.org/article/ab1375b648b54bdda797d99443812184
Autor:
John B. Tucker, Sarah C. Bonema, Rebeca García-Varela, Ryan A. Denu, Yang Hu, Stephanie M. McGregor, Mark E. Burkard, Beth A. Weaver
Publikováno v:
Cancer Research Communications. 3:54-65
Chromosomal instability (CIN), the persistent reshuffling of chromosomes during mitosis, is a hallmark of human cancers that contributes to tumor heterogeneity and has been implicated in driving metastasis and altering responses to therapy. Though mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0792404a5ec4411c77187e0e624a431
https://doi.org/10.1158/2767-9764.crc-22-0302
https://doi.org/10.1158/2767-9764.crc-22-0302
Autor:
Chandra K. Singh, Ryan A. Denu, Minakshi Nihal, Maria Shabbir, Debra R. Garvey, Wei Huang, Kenneth A. Iczkowski, Nihal Ahmad
Publikováno v:
The Prostate. 82:957-969
Identification of novel molecular target(s) is important for designing newer mechanistically driven approaches for the treatment of prostate cancer (PCa), which is one of the main causes of morbidity and mortality in men. In this study, we determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8005bc40a31c635f9e03d9724875d8
https://doi.org/10.1002/pros.24342
https://doi.org/10.1002/pros.24342
Autor:
Beth A. Weaver, Mark E. Burkard, Stephanie M. McGregor, Yang Hu, Ryan A. Denu, Rebeca García-Varela, Sarah C. Bonema, John B. Tucker
Figure S1. Pipeline to assess CIN in primary breast cancer. A. A tissue microarray containing 377 breast cancer and 17 normal breast samples was evaluated for proliferation by Ki67 and CIN based on 6 chromosome FISH (39). H&E stained sections for cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd412ec78b33ce0785ff8a8ecd39e9f
https://doi.org/10.1158/2767-9764.22546133
https://doi.org/10.1158/2767-9764.22546133
Autor:
Beth A. Weaver, Mark E. Burkard, Stephanie M. McGregor, Yang Hu, Ryan A. Denu, Rebeca García-Varela, Sarah C. Bonema, John B. Tucker
Chromosomal instability (CIN), the persistent reshuffling of chromosomes during mitosis, is a hallmark of human cancers that contributes to tumor heterogeneity and has been implicated in driving metastasis and altering responses to therapy. Though mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6a6a0d61550085843e1f30d36336e6
https://doi.org/10.1158/2767-9764.c.6551099.v1
https://doi.org/10.1158/2767-9764.c.6551099.v1
Autor:
Beth A. Weaver, Mark E. Burkard, Stephanie M. McGregor, Yang Hu, Ryan A. Denu, Rebeca García-Varela, Sarah C. Bonema, John B. Tucker
Lagging chromosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee2b57528dbcc504aec57b155660e1e
https://doi.org/10.1158/2767-9764.22546109
https://doi.org/10.1158/2767-9764.22546109
Table TS2 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer
Autor:
Beth A. Weaver, Mark E. Burkard, Stephanie M. McGregor, Yang Hu, Ryan A. Denu, Rebeca García-Varela, Sarah C. Bonema, John B. Tucker
Table S2. Patient characteristics of matched primary and metastatic cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e34ab8e26fb838805f0d447a641c43
https://doi.org/10.1158/2767-9764.22546100.v1
https://doi.org/10.1158/2767-9764.22546100.v1