Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ryan, Zander"'
Publikováno v:
eLife, Vol 11 (2022)
Although recent evidence indicates that CD4+ T cells responding to chronic viral infection are functionally heterogenous, our understanding of the developmental relationships between these subsets, and a determination of how their transcriptional lan
Externí odkaz:
https://doaj.org/article/610c1c6f4f8b4e36b1969d0efefb8e1a
Autor:
Gang Cheng, Micael Hardy, Paytsar Topchyan, Ryan Zander, Peter Volberding, Weiguo Cui, Balaraman Kalyanaraman
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102673- (2021)
Summary: Hydroxyurea (HU), an FDA-approved drug for treating sickle cell disease, is used as an antitumor drug alone and together with conventional chemotherapeutics or radiation therapy. HU is used primarily to treat myeloproliferative diseases beca
Externí odkaz:
https://doaj.org/article/bd646fa91a0e4e0490894678bf35d011
Autor:
Ryan Zander, Weiguo Cui
Publikováno v:
Trends in Immunology. 44:276-286
Autor:
Gang Xin, Ryan Zander, David M. Schauder, Yao Chen, Jason S. Weinstein, William R. Drobyski, Vera Tarakanova, Joseph Craft, Weiguo Cui
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
During chronic infection CD4+ T cells can progressively acquire IL-10 producing functionality. Here the authors use single cell RNA sequencing to interrogate the IL10 CD4+ T cell compartment in a murine model of chronic infection and identify Il10-pr
Externí odkaz:
https://doaj.org/article/5ff106c64d614ee09a1d3854c116a13c
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Immune protection and lasting memory are accomplished through the generation of phenotypically and functionally distinct CD8 T cell subsets. Understanding how these effector and memory T cells are formed is the first step in eventually manipulating t
Externí odkaz:
https://doaj.org/article/dc02f85faa02410cb9f26914f84c403b
Autor:
Weiguo Cui, William A. See, Aimin Jiang, Chunmei Fu, Jian Shen, Yao Chen, Peter J. Volberding, Ryan Zander, Paytsar Topchyan, Achia Khatun, Gang Xin
The quality and quantity of Pmel cells are largely unaltered by temporal depletion of cDC1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e310fdbd6bf337e9b06f0feb2b5ca8f
https://doi.org/10.1158/2326-6066.22542711
https://doi.org/10.1158/2326-6066.22542711
Autor:
Weiguo Cui, William A. See, Aimin Jiang, Chunmei Fu, Jian Shen, Yao Chen, Peter J. Volberding, Ryan Zander, Paytsar Topchyan, Achia Khatun, Gang Xin
List of antibodies and buffers for flow cytometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36eab23e03e4db78b85470eabd47d6f7
https://doi.org/10.1158/2326-6066.22542708.v1
https://doi.org/10.1158/2326-6066.22542708.v1
Autor:
Weiguo Cui, William A. See, Aimin Jiang, Chunmei Fu, Jian Shen, Yao Chen, Peter J. Volberding, Ryan Zander, Paytsar Topchyan, Achia Khatun, Gang Xin
Loss of target antigens in tumor cells has become one of the major hurdles limiting the efficacy of adoptive cell therapy (ACT)–based immunotherapies. The optimal approach to overcome this challenge includes broadening the immune response from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7a2d886f24b13210c461b1ff343b31
https://doi.org/10.1158/2326-6066.c.6550023
https://doi.org/10.1158/2326-6066.c.6550023
Autor:
Ryan Zander, Weiguo Cui
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 10, Pp 2269-2271 (2017)
Recent advancements in adoptive cell therapy (ACT) are opening up new frontiers for cancer immunotherapy. CAR T cells targeting CD19 have emerged as a remarkable T cell-based therapy for the successful treatment of certain types of leukemia and lymph
Externí odkaz:
https://doaj.org/article/dbac7b7f476c48d9810cd86284f22935
Publikováno v:
eLife. 11
Although recent evidence indicates that CD4+T cells responding to chronic viral infection are functionally heterogenous, our understanding of the developmental relationships between these subsets, and a determination of how their transcriptional land