Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ryan, Martin Denis"'
Publikováno v:
Scientific reports. 13(1)
Funding: This work was supported by the Taiwan Ministry of Science and Technology [MOST-106-2911-I-020-501; MOST-107-2313-B-020-011-MY3] and the UK Biotechnology and Biological Sciences Research Council [BB/P025080/1]. Both current live, attenuated,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372e7f0d3bdf509ade840975ff775892
https://pubmed.ncbi.nlm.nih.gov/36609424
https://pubmed.ncbi.nlm.nih.gov/36609424
Autor:
Ryan, Martin Denis
The molecular cloning of enterovirus type 70 (EV70) was achieved using the hybrid (vRNA:cDNA) cloning strategy. Recombinant plasmids containing EV70 sequences were identified by hybridization in situ. EV70 cDNAs were characterized by optical and Smit
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332687
Autor:
Howes, Emma Louise
Foot-and-Mouth Disease Virus (FMDV) is a globally important pathogen responsible for causing Foot-and-Mouth Disease (FMD) in wildlife and domestic livestock species and has significant economic impacts. FMD is difficult to control due to its highly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::ffa0cdf0bcb8450e349eac4738413521
https://hdl.handle.net/10023/15521
https://hdl.handle.net/10023/15521
Autor:
Roulston, Claire
This thesis describes experiments investigating the translational recoding activities and the novel dual signalling properties of eukaryotic ribosome skipping 2A sequences. Over twenty years ago, the 19 amino acid 2A region of a Picornavirus; namely,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::f08f51aaae510f876864496f636031bb
https://hdl.handle.net/10023/7062
https://hdl.handle.net/10023/7062
Autor:
Tulloch, Fiona
Foot-and-mouth disease (FMD) is a highly infectious disease of wild and domestic cloven–hoofed animals such as cattle, swine and deer. It is caused by one of the most contagious animal diseases known; FMD virus (FMDV). Since the disease is endemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::bd29c4a10c3c8a0a0b2e30ff07b5875b
https://hdl.handle.net/10023/6858
https://hdl.handle.net/10023/6858
Autor:
Odon, Valèrie
Originally 2A was characterised in foot-and-mouth disease virus. Site directed mutagenesis identified a C-terminus consensus motif [D(V/I)ExNPGP] and it is proposed that 2A interacts with the exit tunnel of the ribosome in a way that a specific pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f21baf6bc2651ec34a639941ec8397
Autor:
Escuin Ordinas, Helena
Foot-and-mouth disease virus (FMDV) 2A is an oligopeptide composed of only 18 amino acids that can mediate a co-translational cleavage at its own C- terminus. It has been observed that 2A sequences do not show cleavage activity within bacterial organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::bd63b60369f85debab601bc45267c5ed
https://hdl.handle.net/10023/692
https://hdl.handle.net/10023/692
Autor:
Moës, Elien
Picornaviruses replicate in association with cytoplasmic membranes of infected cells. Poliovirus 2C and 2BC play an important role in the formation of membranous vesicles, and induce dramatic changes in membrane trafficking. Theiler’s murine enceph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::ff03a27c0d344c65b4f9ac0724a7ce22
https://hdl.handle.net/10023/540
https://hdl.handle.net/10023/540
Autor:
Kinver, Andrea
Picornavirus-infected cells are characterised by the appearance of smooth vesicles and the disappearance of the Golgi apparatus. Replication of the viral RNA takes place on these virus-induced vesicles. Expression of the viral protein 2BC, and to som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::40a7205b19e8daa9893cbc64578849e9
https://hdl.handle.net/10023/21861
https://hdl.handle.net/10023/21861
Autor:
Byrne, Emma Jane
HRV14 3C acts as a protease and has a role in RNA replication in vivo, interacting with a cloverleaf structure in picornaviral genomic RNA. Picornaviral 3C proteases are able to cleave both N- and C-terminally producing 3CDpro, or, 3Cpro and 3DPol, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::34bbcea8c69b630bb8ed670d0e4f335a
https://hdl.handle.net/10023/14310
https://hdl.handle.net/10023/14310