Multivariate chemogenomic screening prioritizes new macrofilaricidal leads.

Autor: Wheeler, Nicolas J.^1,2 (AUTHOR), Ryan, Kaetlyn T.¹ (AUTHOR), Gallo, Kendra J.¹ (AUTHOR), Henthorn, Clair R.¹ (AUTHOR), Ericksen, Spencer S.³ (AUTHOR), Chan, John D.^1,4 (AUTHOR), Zamanian, Mostafa¹ (AUTHOR) mzamanian@wisc.edu

Publikováno v: Communications Biology. 1/13/2023, Vol. 6 Issue 1, p1-15. 15p.

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Development of non-sedating benzodiazepines with in vivo antischistosomal activity.

Autor: Mian MY; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.; Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Sharmin D; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.; Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Mondal P; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.; Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Belayet JB; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.; Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Hossain MM; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.; Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., McCusker P; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Ryan KT; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA., Fedorov AY; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin, USA., Green HA; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin, USA., Ericksen SS; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin, USA., Zamanian M; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA., Tiruveedhula VVNPB; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Cook JM; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.; Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Chan JD; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Department of Chemistry, University of Wisconsin Oshkosh, Oshkosh, Wisconsin, USA.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 Sep 04; Vol. 68 (9), pp. e0036924. Date of Electronic Publication: 2024 Aug 13.