Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ruzica Kolakovic"'
Autor:
Leena Hanski, Natalja Genina, Hanna Uvell, Kristina Malinovskaja, Åsa Gylfe, Timo Laaksonen, Ruzica Kolakovic, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Mikael Elofsson, Niklas Sandler, Pia M Vuorela
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115115 (2014)
Given the established role of Chlamydia spp. as causative agents of both acute and chronic diseases, search for new antimicrobial agents against these intracellular bacteria is required to promote human health. Isoflavones are naturally occurring phy
Externí odkaz:
https://doaj.org/article/79d6f16c9bfa402aa6e13b698806728e
Autor:
René Holm, Koen Wuyts, Ruzica Kolakovic, Brendan T. Griffin, Martin Kuentz, Filip Cuyckens, Alexandra Roxana Ilie, Maria Vertzoni
Publikováno v:
Drug Development and Industrial Pharmacy
This study aimed to systematically explore compositional effects for a series of lipid systems, on the in vitro drug solubilization and in vivo bioavailability of three poorly water-soluble drugs with different physico-chemical properties. While many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc88a0e5b0bc15833b2590922259b7a
https://hdl.handle.net/10468/10811
https://hdl.handle.net/10468/10811
Autor:
Alexandra Roxana Ilie, Ruzica Kolakovic, Brendan T. Griffin, Hugo Bohets, Maria Vertzoni, Jilly Herman, Ahmed Malash, René Holm, Martin Kuentz, Anke Prudic-Paus
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 159
Supersaturated lipid-based drug delivery systems are increasingly being explored as a bio-enabling formulation approach, particularly in preclinical evaluation of poorlywater-soluble drugs. While increasing the drug load through thermally-induced sup
Autor:
Alexandra-Roxana, Ilie, Brendan T, Griffin, Martin, Brandl, Annette, Bauer-Brandl, Ann-Christin, Jacobsen, Maria, Vertzoni, Martin, Kuentz, Ruzica, Kolakovic, René, Holm
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 152
Supersaturated lipid-based drug delivery systems have recently been investigated for oral administration for a variety of lipophilic drugs and have shown either equivalent or superior oral bioavailability compared to conventional non-supersaturated l
Autor:
Ruzica Kolakovic, Brendan T. Griffin, Maria Vertzoni, Martin Kuentz, Alexandra Roxana Ilie, René Holm
Publikováno v:
Drug Development and Industrial Pharmacy
Objective: The objective of this study was to systematically investigate the impact of lipid composition on the ability to design supersaturated lipid-based drug delivery systems (sLBDDS) using three model drugs with different physico-chemical proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c5e0a1d7d64e65fd1dc8b6ff55d38d
https://hdl.handle.net/10468/9614
https://hdl.handle.net/10468/9614
Autor:
Niklas Sandler, Timo Laaksonen, Anni Määttänen, Ruzica Kolakovic, Natalja Genina, Jouko Peltonen, Mirja Palo, Jarno Salonen
Publikováno v:
International Journal of Pharmaceutics. 494:603-610
The main goal of the current work was to investigate the possible use of flexographic printing for the conversion of nanosuspensions into solid dosage forms. Aqueous nanosuspensions of indomethacin (IND) and itraconazole (ITR) with Poloxamer 407 as t
Publikováno v:
Macromolecular Materials and Engineering. 300:210-217
Oxidised cellulose beads (anionic groups 0.1–1.85mmolg � 1 ) were loaded with ranitidine HCl. Polymorphic form and crystallinity of the drug was assessed by calorimetric and spectrometric techniques. Release profiles were obtained at physiologica
Publikováno v:
Cellulose. 21:1945-1955
Cellulose beads were prepared from water- based solvent and oxidised by modified Anelli's reac- tion at 20-80 � C for 2-48 h (Fig. 1). The maximum amount of anionic groups (AGs) was 1:85 mmol g � 1 . The distribution of AGs was verified by absorp
Autor:
Leena Lyydia Hanski, Pia Vuorela, Mikko Tenho, Emrah Yildir, Jani Trygg, Jukka Rantanen, Martin Gericke, Henrik Ehlers, Pedro Fardim, Ruzica Kolakovic, Niklas Sandler, Natalja Genina
Publikováno v:
International Journal of Pharmaceutics. 456:417-423
In the frame of this work, we have investigated drug entrapping and release abilities of new type of porous cellulose beads (CBs) as a spherical matrix system for drug delivery. For that purpose, CBs prepared with three different methods were used as
Publikováno v:
International Journal of Pharmaceutics. 430:47-55
Nanofibrillar cellulose (also referred to as cellulose nanofibers, nanocellulose, microfibrillated or nanofibrillated cellulose) has gained a lot of attention in recent years in different research areas including biomedical applications. In this stud